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Journal Abstract Search

462 related items for PubMed ID: 26774923

  • 1. Design, synthesis, and biological evaluation of novel thiazolidinediones as PPARγ/FFAR1 dual agonists.
    Darwish KM, Salama I, Mostafa S, Gomaa MS, Helal MA.
    Eur J Med Chem; 2016 Feb 15; 109():157-72. PubMed ID: 26774923
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  • 2. Homology modeling and explicit membrane molecular dynamics simulation to delineate the mode of binding of thiazolidinediones into FFAR1 and the mechanism of receptor activation.
    Helal MA, Darwish KM, Hammad MA.
    Bioorg Med Chem Lett; 2014 Nov 15; 24(22):5330-6. PubMed ID: 25441945
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  • 3. Discovery of new dual PPARγ-GPR40 agonists with robust antidiabetic activity: Design, synthesis and in combo drug evaluation.
    Hidalgo-Figueroa S, Navarrete-Vázquez G, Estrada-Soto S, Giles-Rivas D, Alarcón-Aguilar FJ, León-Rivera I, Giacoman-Martínez A, Miranda Pérez E, Almanza-Pérez JC.
    Biomed Pharmacother; 2017 Jun 15; 90():53-61. PubMed ID: 28342366
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  • 9. PPARγ signaling and emerging opportunities for improved therapeutics.
    Wang S, Dougherty EJ, Danner RL.
    Pharmacol Res; 2016 Sep 15; 111():76-85. PubMed ID: 27268145
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  • 13. Synthesis, docking, in vitro and in vivo antidiabetic activity of pyrazole-based 2,4-thiazolidinedione derivatives as PPAR-γ modulators.
    Naim MJ, Alam O, Alam MJ, Shaquiquzzaman M, Alam MM, Naidu VGM.
    Arch Pharm (Weinheim); 2018 Apr 15; 351(3-4):e1700223. PubMed ID: 29400412
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  • 14. Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-γ/FFAR1 agonists.
    Darwish KM, Salama I, Mostafa S, Gomaa MS, Khafagy ES, Helal MA.
    Bioorg Med Chem Lett; 2018 May 15; 28(9):1595-1602. PubMed ID: 29615345
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  • 15. Rational design and synthesis of some PPAR-γ agonists: Substituted benzylideneamino-benzylidene-thiazolidine-2,4-diones.
    Chhajed SS, Chaskar S, Kshirsagar SK, Haldar GM, Kar Mahapatra D.
    Comput Biol Chem; 2017 Apr 15; 67():260-265. PubMed ID: 28193552
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  • 16. Design, synthesis and biological activity evaluation of a new class of 2,4-thiazolidinedione compounds as insulin enhancers.
    Huiying Z, Guangying C, Shiyang Z.
    J Enzyme Inhib Med Chem; 2019 Dec 15; 34(1):981-989. PubMed ID: 31072232
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  • 17. In silico design, chemical synthesis and toxicological evaluation of 1,3-thiazolidine-2,4-dione derivatives as PPARγ agonists.
    Alemán-González-Duhart D, Tamay-Cach F, Correa-Basurto J, Padilla-Martínez II, Álvarez-Almazán S, Mendieta-Wejebe JE.
    Regul Toxicol Pharmacol; 2017 Jun 15; 86():25-32. PubMed ID: 28202347
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  • 18. Design, synthesis, and structure-activity relationship studies of novel 2,4,6-trisubstituted-5-pyrimidinecarboxylic acids as peroxisome proliferator-activated receptor gamma (PPARgamma) partial agonists with comparable antidiabetic efficacy to rosiglitazone.
    Seto S, Okada K, Kiyota K, Isogai S, Iwago M, Shinozaki T, Kitamura Y, Kohno Y, Murakami K.
    J Med Chem; 2010 Jul 08; 53(13):5012-24. PubMed ID: 20527969
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  • 19. Cinnamic acid based thiazolidinediones inhibit human P450c17 and 3beta-hydroxysteroid dehydrogenase and improve insulin sensitivity independent of PPARgamma agonist activity.
    Arlt W, Neogi P, Gross C, Miller WL.
    J Mol Endocrinol; 2004 Apr 08; 32(2):425-36. PubMed ID: 15072549
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  • 20. Design, Synthesis, and Biological Evaluation of Thiazolidine-2,4-dione Conjugates as PPAR-γ Agonists.
    Nazreen S, Alam MS, Hamid H, Shahar Yar M, Dhulap A, Alam P, Pasha MA, Bano S, Alam MM, Haider S, Kharbanda C, Ali Y, Pillai K.
    Arch Pharm (Weinheim); 2015 Jun 08; 348(6):421-32. PubMed ID: 25900064
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