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455 related items for PubMed ID: 26823761

  • 1. Pyruvate kinase, muscle isoform 2 promotes proliferation and insulin secretion of pancreatic β-cells via activating Wnt/CTNNB1 signaling.
    Wang S, Yang Z, Gao Y, Li Q, Su Y, Wang Y, Zhang Y, Man H, Liu H.
    Int J Clin Exp Pathol; 2015; 8(11):14441-8. PubMed ID: 26823761
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  • 5. L-cysteine reversibly inhibits glucose-induced biphasic insulin secretion and ATP production by inactivating PKM2.
    Nakatsu D, Horiuchi Y, Kano F, Noguchi Y, Sugawara T, Takamoto I, Kubota N, Kadowaki T, Murata M.
    Proc Natl Acad Sci U S A; 2015 Mar 10; 112(10):E1067-76. PubMed ID: 25713368
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  • 6. PKM2 gene regulates the behavior of pancreatic cancer cells via mitogen-activated protein kinase pathways.
    Feng J, Ma T, Ge Z, Lin J, Ding W, Chen H, Zhu W, Zhou S, Tan Y.
    Mol Med Rep; 2015 Mar 10; 11(3):2111-7. PubMed ID: 25411978
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  • 7. Wnt3a regulates proliferation, apoptosis and function of pancreatic NIT-1 beta cells via activation of IRS2/PI3K signaling.
    Gui S, Yuan G, Wang L, Zhou L, Xue Y, Yu Y, Zhang J, Zhang M, Yang Y, Wang DW.
    J Cell Biochem; 2013 Jul 10; 114(7):1488-97. PubMed ID: 23296977
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  • 8. Mechanisms of pyruvate kinase M2 isoform inhibits cell motility in hepatocellular carcinoma cells.
    Chen YL, Song JJ, Chen XC, Xu W, Zhi Q, Liu YP, Xu HZ, Pan JS, Ren JL, Guleng B.
    World J Gastroenterol; 2015 Aug 14; 21(30):9093-102. PubMed ID: 26290635
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  • 9. APC loss induces Warburg effect via increased PKM2 transcription in colorectal cancer.
    Cha PH, Hwang JH, Kwak DK, Koh E, Kim KS, Choi KY.
    Br J Cancer; 2021 Feb 14; 124(3):634-644. PubMed ID: 33071283
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  • 10. Effects of PKM2 Gene Silencing on the Proliferation and Apoptosis of Colorectal Cancer LS-147T and SW620 Cells.
    Ao R, Guan L, Wang Y, Wang JN.
    Cell Physiol Biochem; 2017 Feb 14; 42(5):1769-1778. PubMed ID: 28746922
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  • 11. FGF19 Promotes the Proliferation and Insulin Secretion from Human Pancreatic β Cells Via the IRS1/GLUT4 Pathway.
    Zeng T, Tang X, Bai X, Xiong H.
    Exp Clin Endocrinol Diabetes; 2024 Mar 14; 132(3):152-161. PubMed ID: 38513652
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  • 12. MicroRNA-19a-3p enhances the proliferation and insulin secretion, while it inhibits the apoptosis of pancreatic β cells via the inhibition of SOCS3.
    Li Y, Luo T, Wang L, Wu J, Guo S.
    Int J Mol Med; 2016 Nov 14; 38(5):1515-1524. PubMed ID: 27666763
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  • 13. Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells.
    Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA.
    Diabetes; 2008 May 14; 57(5):1195-204. PubMed ID: 18276765
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  • 14. Epigenetic silencing of miR-338 facilitates glioblastoma progression by de-repressing the pyruvate kinase M2-β-catenin axis.
    Han B, Meng X, Chen H, Chen L, Liu X, Wang H, Liu D, Gao F, Lin L, Ming J, Sun B, Yin S, Wang R, Wu P, Cai J, Jiang C.
    Aging (Albany NY); 2017 Aug 02; 9(8):1885-1897. PubMed ID: 28858851
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  • 15. Inhibiting the Pkm2/b-catenin axis drives in vivo replication of adult cardiomyocytes following experimental MI.
    Hauck L, Dadson K, Chauhan S, Grothe D, Billia F.
    Cell Death Differ; 2021 Apr 02; 28(4):1398-1417. PubMed ID: 33288902
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  • 16. PKM2 depletion induces the compensation of glutaminolysis through β-catenin/c-Myc pathway in tumor cells.
    Wu H, Li Z, Yang P, Zhang L, Fan Y, Li Z.
    Cell Signal; 2014 Nov 02; 26(11):2397-405. PubMed ID: 25041845
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  • 17. The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition.
    Brandi J, Cecconi D, Cordani M, Torrens-Mas M, Pacchiana R, Dalla Pozza E, Butera G, Manfredi M, Marengo E, Oliver J, Roca P, Dando I, Donadelli M.
    Free Radic Biol Med; 2016 Dec 02; 101():305-316. PubMed ID: 27989750
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  • 18. Chikusetsu saponin IVa protects pancreatic β cell against intermittent high glucose-induced injury by activating Wnt/β-catenin/TCF7L2 pathway.
    Cui J, Duan J, Chu J, Guo C, Xi M, Li Y, Weng Y, Wei G, Yin Y, Wen A, Qiao B.
    Aging (Albany NY); 2020 Jan 22; 12(2):1591-1609. PubMed ID: 31969494
    [Abstract] [Full Text] [Related]

  • 19. Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinoma.
    Hu W, Lu SX, Li M, Zhang C, Liu LL, Fu J, Jin JT, Luo RZ, Zhang CZ, Yun JP.
    Oncotarget; 2015 Mar 30; 6(9):6570-83. PubMed ID: 25788265
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  • 20. Pancreatic-β-cell survival and proliferation are promoted by protein kinase G type Iα and downstream regulation of AKT/FOXO1.
    Wong JC, Vo V, Gorjala P, Fiscus RR.
    Diab Vasc Dis Res; 2017 Sep 30; 14(5):434-449. PubMed ID: 28631500
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