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Journal Abstract Search

279 related items for PubMed ID: 26836397

  • 1. Molecular inflation, attrition and the rule of five.
    Leeson PD.
    Adv Drug Deliv Rev; 2016 Jun 01; 101():22-33. PubMed ID: 26836397
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  • 4. Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space.
    Meanwell NA.
    Chem Res Toxicol; 2016 Apr 18; 29(4):564-616. PubMed ID: 26974882
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  • 7. The influence of the 'organizational factor' on compound quality in drug discovery.
    Leeson PD, St-Gallay SA.
    Nat Rev Drug Discov; 2011 Sep 30; 10(10):749-65. PubMed ID: 21959288
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  • 8. Lipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility.
    Naylor MR, Ly AM, Handford MJ, Ramos DP, Pye CR, Furukawa A, Klein VG, Noland RP, Edmondson Q, Turmon AC, Hewitt WM, Schwochert J, Townsend CE, Kelly CN, Blanco MJ, Lokey RS.
    J Med Chem; 2018 Dec 27; 61(24):11169-11182. PubMed ID: 30395703
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  • 9. A new paradigm for navigating compound property related drug attrition.
    Barton P, Riley RJ.
    Drug Discov Today; 2016 Jan 27; 21(1):72-81. PubMed ID: 26404453
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  • 10. Computational prediction of formulation strategies for beyond-rule-of-5 compounds.
    Bergström CAS, Charman WN, Porter CJH.
    Adv Drug Deliv Rev; 2016 Jun 01; 101():6-21. PubMed ID: 26928657
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  • 12. Practical application of ligand efficiency metrics in lead optimisation.
    Scott JS, Waring MJ.
    Bioorg Med Chem; 2018 Jul 15; 26(11):3006-3015. PubMed ID: 29655612
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