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917 related items for PubMed ID: 26847819

  • 1. Metformin inhibits growth of human non-small cell lung cancer cells via liver kinase B-1-independent activation of adenosine monophosphate-activated protein kinase.
    Guo Q, Liu Z, Jiang L, Liu M, Ma J, Yang C, Han L, Nan K, Liang X.
    Mol Med Rep; 2016 Mar; 13(3):2590-6. PubMed ID: 26847819
    [Abstract] [Full Text] [Related]

  • 2. Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.
    Lin CC, Yeh HH, Huang WL, Yan JJ, Lai WW, Su WP, Chen HH, Su WC.
    Am J Respir Cell Mol Biol; 2013 Aug; 49(2):241-50. PubMed ID: 23526220
    [Abstract] [Full Text] [Related]

  • 3. Synergistic effects of metformin treatment in combination with gefitinib, a selective EGFR tyrosine kinase inhibitor, in LKB1 wild-type NSCLC cell lines.
    Morgillo F, Sasso FC, Della Corte CM, Vitagliano D, D'Aiuto E, Troiani T, Martinelli E, De Vita F, Orditura M, De Palma R, Ciardiello F.
    Clin Cancer Res; 2013 Jul 01; 19(13):3508-19. PubMed ID: 23695170
    [Abstract] [Full Text] [Related]

  • 4. Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth.
    Rocha GZ, Dias MM, Ropelle ER, Osório-Costa F, Rossato FA, Vercesi AE, Saad MJ, Carvalheira JB.
    Clin Cancer Res; 2011 Jun 15; 17(12):3993-4005. PubMed ID: 21543517
    [Abstract] [Full Text] [Related]

  • 5. Negative regulation of the LKB1/AMPK pathway by ERK in human acute myeloid leukemia cells.
    Kawashima I, Mitsumori T, Nozaki Y, Yamamoto T, Shobu-Sueki Y, Nakajima K, Kirito K.
    Exp Hematol; 2015 Jul 15; 43(7):524-33.e1. PubMed ID: 25846811
    [Abstract] [Full Text] [Related]

  • 6. Cation-selective transporters are critical to the AMPK-mediated antiproliferative effects of metformin in human breast cancer cells.
    Cai H, Zhang Y, Han TK, Everett RS, Thakker DR.
    Int J Cancer; 2016 May 01; 138(9):2281-92. PubMed ID: 26669511
    [Abstract] [Full Text] [Related]

  • 7. Baicalin, a Chinese Herbal Medicine, Inhibits the Proliferation and Migration of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells, A549 and H1299, by Activating the SIRT1/AMPK Signaling Pathway.
    You J, Cheng J, Yu B, Duan C, Peng J.
    Med Sci Monit; 2018 Apr 10; 24():2126-2133. PubMed ID: 29632297
    [Abstract] [Full Text] [Related]

  • 8. Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner.
    Rattan R, Giri S, Hartmann LC, Shridhar V.
    J Cell Mol Med; 2011 Jan 10; 15(1):166-78. PubMed ID: 19874425
    [Abstract] [Full Text] [Related]

  • 9. Nootkatone, an AMPK activator derived from grapefruit, inhibits KRAS downstream pathway and sensitizes non-small-cell lung cancer A549 cells to adriamycin.
    Hung LVM, Moon JY, Ryu JY, Cho SK.
    Phytomedicine; 2019 Oct 10; 63():153000. PubMed ID: 31280139
    [Abstract] [Full Text] [Related]

  • 10. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.
    Han S, Khuri FR, Roman J.
    Cancer Res; 2006 Jan 01; 66(1):315-23. PubMed ID: 16397245
    [Abstract] [Full Text] [Related]

  • 11. Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.
    Nagalingam A, Arbiser JL, Bonner MY, Saxena NK, Sharma D.
    Breast Cancer Res; 2012 Feb 21; 14(1):R35. PubMed ID: 22353783
    [Abstract] [Full Text] [Related]

  • 12. LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells.
    Li C, Liu VW, Chan DW, Yao KM, Ngan HY.
    Int J Gynecol Cancer; 2012 Jan 21; 22(1):15-22. PubMed ID: 22080879
    [Abstract] [Full Text] [Related]

  • 13. LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells.
    Li NS, Zou JR, Lin H, Ke R, He XL, Xiao L, Huang D, Luo L, Lv N, Luo Z.
    Tumour Biol; 2016 Jun 21; 37(6):8249-58. PubMed ID: 26718214
    [Abstract] [Full Text] [Related]

  • 14. Metformin induces autophagy and G0/G1 phase cell cycle arrest in myeloma by targeting the AMPK/mTORC1 and mTORC2 pathways.
    Wang Y, Xu W, Yan Z, Zhao W, Mi J, Li J, Yan H.
    J Exp Clin Cancer Res; 2018 Mar 20; 37(1):63. PubMed ID: 29554968
    [Abstract] [Full Text] [Related]

  • 15. Carnosic Acid against Lung Cancer: Induction of Autophagy and Activation of Sestrin-2/LKB1/AMPK Signalling.
    O'Neill EJ, Sze NSK, MacPherson REK, Tsiani E.
    Int J Mol Sci; 2024 Feb 06; 25(4):. PubMed ID: 38396629
    [Abstract] [Full Text] [Related]

  • 16. Sauchinone exerts anticancer effects by targeting AMPK signaling in hepatocellular carcinoma cells.
    Kim YW, Jang EJ, Kim CH, Lee JH.
    Chem Biol Interact; 2017 Jan 05; 261():108-117. PubMed ID: 27871897
    [Abstract] [Full Text] [Related]

  • 17. Galangin inhibits proliferation of HepG2 cells by activating AMPK via increasing the AMP/TAN ratio in a LKB1-independent manner.
    Zhang H, Li N, Wu J, Su L, Chen X, Lin B, Luo H.
    Eur J Pharmacol; 2013 Oct 15; 718(1-3):235-44. PubMed ID: 24028940
    [Abstract] [Full Text] [Related]

  • 18. The antidiabetic drug metformin inhibits uterine leiomyoma cell proliferation via an AMP-activated protein kinase signaling pathway.
    Li B, Takeda T, Tsuiji K, Kondo A, Kitamura M, Wong TF, Yaegashi N.
    Gynecol Endocrinol; 2013 Jan 15; 29(1):87-90. PubMed ID: 22835064
    [Abstract] [Full Text] [Related]

  • 19. Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma.
    Zheng L, Yang W, Wu F, Wang C, Yu L, Tang L, Qiu B, Li Y, Guo L, Wu M, Feng G, Zou D, Wang H.
    Clin Cancer Res; 2013 Oct 01; 19(19):5372-80. PubMed ID: 23942093
    [Abstract] [Full Text] [Related]

  • 20. Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells.
    Della Corte CM, Ciaramella V, Di Mauro C, Castellone MD, Papaccio F, Fasano M, Sasso FC, Martinelli E, Troiani T, De Vita F, Orditura M, Bianco R, Ciardiello F, Morgillo F.
    Oncotarget; 2016 Jan 26; 7(4):4265-78. PubMed ID: 26673006
    [Abstract] [Full Text] [Related]

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