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294 related items for PubMed ID: 26858456

  • 1. Endocytosis separates EGF receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomes.
    Pinilla-Macua I, Watkins SC, Sorkin A.
    Proc Natl Acad Sci U S A; 2016 Feb 23; 113(8):2122-7. PubMed ID: 26858456
    [Abstract] [Full Text] [Related]

  • 2. Live-cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosis.
    Fortian A, Sorkin A.
    J Cell Sci; 2014 Jan 15; 127(Pt 2):432-44. PubMed ID: 24259669
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of the Ras-ERK pathway in mitotic COS7 cells is due to the inability of EGFR/Raf to transduce EGF signaling to downstream proteins.
    Shi H, Zhang T, Yi Y, Ma Y.
    Oncol Rep; 2016 Jun 15; 35(6):3593-9. PubMed ID: 27004682
    [Abstract] [Full Text] [Related]

  • 4. Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells.
    Jiang X, Sorkin A.
    Mol Biol Cell; 2002 May 15; 13(5):1522-35. PubMed ID: 12006650
    [Abstract] [Full Text] [Related]

  • 5. Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF.
    Oksvold MP, Skarpen E, Wierød L, Paulsen RE, Huitfeldt HS.
    Eur J Cell Biol; 2001 Apr 15; 80(4):285-94. PubMed ID: 11370743
    [Abstract] [Full Text] [Related]

  • 6. EGFR-RAS-MAPK signaling is confined to the plasma membrane and associated endorecycling protrusions.
    Surve S, Watkins SC, Sorkin A.
    J Cell Biol; 2021 Nov 01; 220(11):. PubMed ID: 34515735
    [Abstract] [Full Text] [Related]

  • 7. Localization dynamics of endogenous fluorescently labeled RAF1 in EGF-stimulated cells.
    Surve SV, Myers PJ, Clayton SA, Watkins SC, Lazzara MJ, Sorkin A.
    Mol Biol Cell; 2019 Feb 15; 30(4):506-523. PubMed ID: 30586319
    [Abstract] [Full Text] [Related]

  • 8. SPIN90 knockdown attenuates the formation and movement of endosomal vesicles in the early stages of epidermal growth factor receptor endocytosis.
    Oh H, Kim H, Chung KH, Hong NH, Shin B, Park WJ, Jun Y, Rhee S, Song WK.
    PLoS One; 2013 Feb 15; 8(12):e82610. PubMed ID: 24340049
    [Abstract] [Full Text] [Related]

  • 9. Role of Ras in metal-induced EGF receptor signaling and NF-kappaB activation in human airway epithelial cells.
    Wu W, Jaspers I, Zhang W, Graves LM, Samet JM.
    Am J Physiol Lung Cell Mol Physiol; 2002 May 15; 282(5):L1040-8. PubMed ID: 11943669
    [Abstract] [Full Text] [Related]

  • 10. Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits.
    Johannessen LE, Pedersen NM, Pedersen KW, Madshus IH, Stang E.
    Mol Cell Biol; 2006 Jan 15; 26(2):389-401. PubMed ID: 16382132
    [Abstract] [Full Text] [Related]

  • 11. Flotillin-1/reggie-2 protein plays dual role in activation of receptor-tyrosine kinase/mitogen-activated protein kinase signaling.
    Amaddii M, Meister M, Banning A, Tomasovic A, Mooz J, Rajalingam K, Tikkanen R.
    J Biol Chem; 2012 Mar 02; 287(10):7265-78. PubMed ID: 22232557
    [Abstract] [Full Text] [Related]

  • 12. α-Lipoic acid inhibits human lung cancer cell proliferation through Grb2-mediated EGFR downregulation.
    Yang L, Wen Y, Lv G, Lin Y, Tang J, Lu J, Zhang M, Liu W, Sun X.
    Biochem Biophys Res Commun; 2017 Dec 09; 494(1-2):325-331. PubMed ID: 28993193
    [Abstract] [Full Text] [Related]

  • 13. [INHIBITORS OF MAP-KINASE PATHWAY U0126 AND PD98059 DIFFERENTLY AFFECT ORGANIZATION OF TUBULIN CYTOSKELETON AFTER STIMULATION OF EGF RECEPTOR ENDOCYTOSIS].
    Zlobina MV, Steblyanko YY, Shklyaeva MA, Kharchenko VV, Salova AV, Kornilova ES.
    Tsitologiia; 2015 Dec 09; 57(4):269-77. PubMed ID: 26349244
    [Abstract] [Full Text] [Related]

  • 14. Regulation of the EGF transcriptional response by endocytic sorting.
    Brankatschk B, Wichert SP, Johnson SD, Schaad O, Rossner MJ, Gruenberg J.
    Sci Signal; 2012 Mar 13; 5(215):ra21. PubMed ID: 22416276
    [Abstract] [Full Text] [Related]

  • 15. Epidermal Growth Factor Receptor Signaling to the Mitogen Activated Protein Kinase Pathway Bypasses Ras in Pancreatic Cancer Cells.
    Lee S, Heinrich EL, Lu J, Lee W, Choi AH, Luu C, Chung V, Fakih M, Kim J.
    Pancreas; 2016 Feb 13; 45(2):286-92. PubMed ID: 26262587
    [Abstract] [Full Text] [Related]

  • 16. Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways.
    Huang L, Watanabe M, Chikamori M, Kido Y, Yamamoto T, Shibuya M, Gotoh N, Tsuchida N.
    Oncogene; 2006 Oct 19; 25(49):6457-66. PubMed ID: 16702953
    [Abstract] [Full Text] [Related]

  • 17. Endothelium-derived nitric oxide (NO) activates the NO-epidermal growth factor receptor-mediated signaling pathway in bradykinin-stimulated angiogenesis.
    Moraes MS, Costa PE, Batista WL, Paschoalin T, Curcio MF, Borges RE, Taha MO, Fonseca FV, Stern A, Monteiro HP.
    Arch Biochem Biophys; 2014 Sep 15; 558():14-27. PubMed ID: 24960080
    [Abstract] [Full Text] [Related]

  • 18. Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.
    Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J.
    Nucleic Acids Res; 2016 Dec 01; 44(21):10150-10164. PubMed ID: 27587583
    [Abstract] [Full Text] [Related]

  • 19. Gab1 signaling is regulated by EGF receptor sorting in early endosomes.
    Kostenko O, Tsacoumangos A, Crooks D, Kil SJ, Carlin C.
    Oncogene; 2006 Oct 26; 25(50):6604-17. PubMed ID: 16715136
    [Abstract] [Full Text] [Related]

  • 20. EGF‑stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in a gefitinib‑resistant human lung cancer cell line.
    Nishimura Y, Takiguchi S, Ito S, Itoh K.
    Int J Oncol; 2015 Apr 26; 46(4):1721-9. PubMed ID: 25653196
    [Abstract] [Full Text] [Related]

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