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Journal Abstract Search

203 related items for PubMed ID: 26871658

  • 1. Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents.
    Zhang L, Addla D, Ponmani J, Wang A, Xie D, Wang YN, Zhang SL, Geng RX, Cai GX, Li S, Zhou CH.
    Eur J Med Chem; 2016 Mar 23; 111():160-82. PubMed ID: 26871658
    [Abstract] [Full Text] [Related]

  • 2. Discovery of Novel 7-[(1R,5S)-1-Amino-5-fluoro-3-azabicyclo[3.3.0]octan-3-yl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropane]-8-(methoxy or methyl)quinolones.
    Komoriya S, Odagiri T, Inagaki H, Nagamochi M, Miyauchi R, Yoshida KI, Kitamura T, Takahashi H.
    Chem Pharm Bull (Tokyo); 2019 Mar 23; 67(1):47-58. PubMed ID: 30606950
    [Abstract] [Full Text] [Related]

  • 3. Discovery of Benzimidazole-Quinolone Hybrids as New Cleaving Agents toward Drug-Resistant Pseudomonas aeruginosa DNA.
    Wang YN, Bheemanaboina RRY, Gao WW, Kang J, Cai GX, Zhou CH.
    ChemMedChem; 2018 May 23; 13(10):1004-1017. PubMed ID: 29512892
    [Abstract] [Full Text] [Related]

  • 4. Novel aminopyrimidinyl benzimidazoles as potentially antimicrobial agents: Design, synthesis and biological evaluation.
    Liu HB, Gao WW, Tangadanchu VKR, Zhou CH, Geng RX.
    Eur J Med Chem; 2018 Jan 01; 143():66-84. PubMed ID: 29172083
    [Abstract] [Full Text] [Related]

  • 5. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects.
    Ibrahim NM, Fahim SH, Hassan M, Farag AE, Georgey HH.
    Eur J Med Chem; 2022 Jan 15; 228():114021. PubMed ID: 34871841
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents.
    Fedorowicz J, Sączewski J, Konopacka A, Waleron K, Lejnowski D, Ciura K, Tomašič T, Skok Ž, Savijoki K, Morawska M, Gilbert-Girard S, Fallarero A.
    Eur J Med Chem; 2019 Oct 01; 179():576-590. PubMed ID: 31279292
    [Abstract] [Full Text] [Related]

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  • 8. Design, synthesis and biological evaluation of 5-fluorouracil-derived benzimidazoles as novel type of potential antimicrobial agents.
    Fang XJ, Jeyakkumar P, Avula SR, Zhou Q, Zhou CH.
    Bioorg Med Chem Lett; 2016 Jun 01; 26(11):2584-8. PubMed ID: 27117429
    [Abstract] [Full Text] [Related]

  • 9. New developments in non-quinolone-based antibiotics for the inhibiton of bacterial gyrase and topoisomerase IV.
    Badshah SL, Ullah A.
    Eur J Med Chem; 2018 May 25; 152():393-400. PubMed ID: 29751233
    [Abstract] [Full Text] [Related]

  • 10. Novel bacterial topoisomerase inhibitors derived from isomannide.
    Okumu A, Lu Y, Dellos-Nolan S, Papa JL, Koci B, Cockroft NT, Gallucci J, Wozniak DJ, Yalowich JC, Mitton-Fry MJ.
    Eur J Med Chem; 2020 Aug 01; 199():112324. PubMed ID: 32402932
    [Abstract] [Full Text] [Related]

  • 11. Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria.
    Ho SY, Wang W, Ng FM, Wong YX, Poh ZY, Tan SWE, Ang SH, Liew SS, Joyner Wong YS, Tan Y, Poulsen A, Pendharkar V, Sangthongpitag K, Manchester J, Basarab G, Hill J, Keller TH, Cherian J.
    Eur J Med Chem; 2018 Sep 05; 157():610-621. PubMed ID: 30125722
    [Abstract] [Full Text] [Related]

  • 12. A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and topoisomerase IV.
    Wang LL, Battini N, Bheemanaboina RRY, Ansari MF, Chen JP, Xie YP, Cai GX, Zhang SL, Zhou CH.
    Eur J Med Chem; 2019 Oct 01; 179():166-181. PubMed ID: 31254919
    [Abstract] [Full Text] [Related]

  • 13. Novel 3-Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism.
    Cui SF, Addla D, Zhou CH.
    J Med Chem; 2016 May 26; 59(10):4488-510. PubMed ID: 27115717
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and structure-activity relationship studies of 4-arylthiosemicarbazides as topoisomerase IV inhibitors with Gram-positive antibacterial activity. Search for molecular basis of antibacterial activity of thiosemicarbazides.
    Siwek A, Stączek P, Stefańska J.
    Eur J Med Chem; 2011 Nov 26; 46(11):5717-26. PubMed ID: 21978836
    [Abstract] [Full Text] [Related]

  • 15. Discovery of (3S)-amino-(4R)-ethylpiperidinyl quinolones as potent antibacterial agents with a broad spectrum of activity and activity against resistant pathogens.
    Hu XE, Kim NK, Gray JL, Almstead JI, Seibel WL, Ledoussal B.
    J Med Chem; 2003 Aug 14; 46(17):3655-61. PubMed ID: 12904069
    [Abstract] [Full Text] [Related]

  • 16. Multi-targeting exploration of new 2-aminothiazolyl quinolones: Synthesis, antimicrobial evaluation, interaction with DNA, combination with topoisomerase IV and penetrability into cells.
    Cheng Y, Avula SR, Gao WW, Addla D, Tangadanchu VKR, Zhang L, Lin JM, Zhou CH.
    Eur J Med Chem; 2016 Nov 29; 124():935-945. PubMed ID: 27769037
    [Abstract] [Full Text] [Related]

  • 17. In vitro Antibacterial Activity of 7-Substituted-6-Fluoroquinolone and 7-Substituted-6,8-Difluoroquinolone Derivatives.
    Leyva-Ramos S, de Loera D, Cardoso-Ortiz J.
    Chemotherapy; 2017 Nov 29; 62(3):194-198. PubMed ID: 28334702
    [Abstract] [Full Text] [Related]

  • 18. One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor.
    Salem MA, Ragab A, Askar AA, El-Khalafawy A, Makhlouf AH.
    Eur J Med Chem; 2020 Feb 15; 188():111977. PubMed ID: 31927313
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity.
    Surivet JP, Zumbrunn C, Rueedi G, Hubschwerlen C, Bur D, Bruyère T, Locher H, Ritz D, Keck W, Seiler P, Kohl C, Gauvin JC, Mirre A, Kaegi V, Dos Santos M, Gaertner M, Delers J, Enderlin-Paput M, Boehme M.
    J Med Chem; 2013 Sep 26; 56(18):7396-415. PubMed ID: 23968485
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and antibacterial activity of quinolone-based compounds containing a coumarin moiety.
    Emami S, Foroumadi A, Faramarzi MA, Samadi N.
    Arch Pharm (Weinheim); 2008 Jan 26; 341(1):42-8. PubMed ID: 18072241
    [Abstract] [Full Text] [Related]

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