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Journal Abstract Search

536 related items for PubMed ID: 26895791

  • 1. Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1-40/42 and Phospho-Tau May Abet Alzheimer Development.
    Sajan M, Hansen B, Ivey R, Sajan J, Ari C, Song S, Braun U, Leitges M, Farese-Higgs M, Farese RV.
    Diabetes; 2016 Jul; 65(7):1892-903. PubMed ID: 26895791
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  • 2. Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.
    Sajan MP, Lee MC, Foufelle F, Sajan J, Cleland C, Farese RV.
    Cell Signal; 2018 Mar; 43():62-70. PubMed ID: 29269047
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  • 3. BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans.
    Sajan MP, Ivey RA, Farese RV.
    Metabolism; 2015 Nov; 64(11):1454-65. PubMed ID: 26386696
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  • 4. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
    Sajan MP, Ivey RA, Lee MC, Farese RV.
    J Lipid Res; 2015 Jan; 56(1):70-80. PubMed ID: 25395359
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  • 8. Spexin alleviates insulin resistance and inhibits hepatic gluconeogenesis via the FoxO1/PGC-1α pathway in high-fat-diet-induced rats and insulin resistant cells.
    Gu L, Ding X, Wang Y, Gu M, Zhang J, Yan S, Li N, Song Z, Yin J, Lu L, Peng Y.
    Int J Biol Sci; 2019 Jan; 15(13):2815-2829. PubMed ID: 31853220
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  • 9. PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.
    Southgate RJ, Bruce CR, Carey AL, Steinberg GR, Walder K, Monks R, Watt MJ, Hawley JA, Birnbaum MJ, Febbraio MA.
    FASEB J; 2005 Dec; 19(14):2072-4. PubMed ID: 16203862
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  • 10. IGF-II-mediated downregulation of peroxisome proliferator-activated receptor-γ coactivator-1α in myoblast cells involves PI3K/Akt/FoxO1 signaling pathway.
    Mu X, Qi W, Liu Y, Zhou J, Li Y, Rong X, Lu L.
    Mol Cell Biochem; 2017 Aug; 432(1-2):199-208. PubMed ID: 28374141
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  • 11. Akt-dependent phosphorylation of hepatic FoxO1 is compartmentalized on a WD40/ProF scaffold and is selectively inhibited by aPKC in early phases of diet-induced obesity.
    Sajan MP, Acevedo-Duncan ME, Standaert ML, Ivey RA, Lee M, Farese RV.
    Diabetes; 2014 Aug; 63(8):2690-701. PubMed ID: 24705403
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  • 12. Evaluation of Neuropathological Effects of a High-Fat Diet in a Presymptomatic Alzheimer's Disease Stage in APP/PS1 Mice.
    Ettcheto M, Petrov D, Pedrós I, Alva N, Carbonell T, Beas-Zarate C, Pallas M, Auladell C, Folch J, Camins A.
    J Alzheimers Dis; 2016 Jul 14; 54(1):233-51. PubMed ID: 27567882
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  • 13. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.
    Ho L, Qin W, Pompl PN, Xiang Z, Wang J, Zhao Z, Peng Y, Cambareri G, Rocher A, Mobbs CV, Hof PR, Pasinetti GM.
    FASEB J; 2004 May 14; 18(7):902-4. PubMed ID: 15033922
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  • 16. Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity.
    Penniman CM, Suarez Beltran PA, Bhardwaj G, Junck TL, Jena J, Poro K, Hirshman MF, Goodyear LJ, O'Neill BT.
    Mol Metab; 2019 Dec 14; 30():203-220. PubMed ID: 31767172
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  • 17. High-fat diet-induced renal cell apoptosis and oxidative stress in spontaneously hypertensive rat are ameliorated by fenofibrate through the PPARα-FoxO3a-PGC-1α pathway.
    Chung HW, Lim JH, Kim MY, Shin SJ, Chung S, Choi BS, Kim HW, Kim YS, Park CW, Chang YS.
    Nephrol Dial Transplant; 2012 Jun 14; 27(6):2213-25. PubMed ID: 22076434
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  • 18. Hyperphosphorylation of Tau induced by naturally secreted amyloid-β at nanomolar concentrations is modulated by insulin-dependent Akt-GSK3β signaling pathway.
    Tokutake T, Kasuga K, Yajima R, Sekine Y, Tezuka T, Nishizawa M, Ikeuchi T.
    J Biol Chem; 2012 Oct 12; 287(42):35222-35233. PubMed ID: 22910909
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  • 19. Capsaicin reduces Alzheimer-associated tau changes in the hippocampus of type 2 diabetes rats.
    Xu W, Liu J, Ma D, Yuan G, Lu Y, Yang Y.
    PLoS One; 2017 Oct 12; 12(2):e0172477. PubMed ID: 28225806
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  • 20. Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction.
    Al-Regaiey KA, Masternak MM, Bonkowski M, Sun L, Bartke A.
    Endocrinology; 2005 Feb 12; 146(2):851-60. PubMed ID: 15498882
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