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Journal Abstract Search

334 related items for PubMed ID: 26919061

  • 1. A novel microtubule depolymerizing colchicine analogue triggers apoptosis and autophagy in HCT-116 colon cancer cells.
    Kumar A, Singh B, Sharma PR, Bharate SB, Saxena AK, Mondhe DM.
    Cell Biochem Funct; 2016 Mar; 34(2):69-81. PubMed ID: 26919061
    [Abstract] [Full Text] [Related]

  • 2. A novel colchicine-based microtubule inhibitor exhibits potent antitumor activity by inducing mitochondrial mediated apoptosis in MIA PaCa-2 pancreatic cancer cells.
    Kumar A, Singh B, Mahajan G, Sharma PR, Bharate SB, Mintoo MJ, Mondhe DM.
    Tumour Biol; 2016 Oct; 37(10):13121-13136. PubMed ID: 27449046
    [Abstract] [Full Text] [Related]

  • 3. Colchicine induces autophagy and senescence in lung cancer cells at clinically admissible concentration: potential use of colchicine in combination with autophagy inhibitor in cancer therapy.
    Bhattacharya S, Das A, Datta S, Ganguli A, Chakrabarti G.
    Tumour Biol; 2016 Aug; 37(8):10653-64. PubMed ID: 26867767
    [Abstract] [Full Text] [Related]

  • 4. Novel analogue of colchicine induces selective pro-death autophagy and necrosis in human cancer cells.
    Larocque K, Ovadje P, Djurdjevic S, Mehdi M, Green J, Pandey S.
    PLoS One; 2014 Aug; 9(1):e87064. PubMed ID: 24466327
    [Abstract] [Full Text] [Related]

  • 5. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
    Cai D, Qiu Z, Yao W, Liu Y, Huang H, Liao S, Luo Q, Xie L, Lin Z.
    Cancer Chemother Pharmacol; 2016 Jun; 77(6):1217-29. PubMed ID: 27107592
    [Abstract] [Full Text] [Related]

  • 6. Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization.
    Schneider Y, Chabert P, Stutzmann J, Coelho D, Fougerousse A, Gossé F, Launay JF, Brouillard R, Raul F.
    Int J Cancer; 2003 Nov 01; 107(2):189-96. PubMed ID: 12949793
    [Abstract] [Full Text] [Related]

  • 7. Colchicine derivatives with potent anticancer activity and reduced P-glycoprotein induction liability.
    Singh B, Kumar A, Joshi P, Guru SK, Kumar S, Wani ZA, Mahajan G, Hussain A, Qazi AK, Kumar A, Bharate SS, Gupta BD, Sharma PR, Hamid A, Saxena AK, Mondhe DM, Bhushan S, Bharate SB, Vishwakarma RA.
    Org Biomol Chem; 2015 May 28; 13(20):5674-89. PubMed ID: 25895604
    [Abstract] [Full Text] [Related]

  • 8. New Combretastatin Analogs as Anticancer Agents: Design, Synthesis, Microtubules Polymerization Inhibition, and Molecular Docking Studies.
    Abdul Hussein SA, Razzak Mahmood AA, Tahtamouni LH, Balakit AA, Yaseen YS, Al-Hasani RA.
    Chem Biodivers; 2023 Apr 28; 20(4):e202201206. PubMed ID: 36890635
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and biological evaluation of colchicine derivatives as novel tubulin and histone deacetylase dual inhibitors.
    Zhang X, Kong Y, Zhang J, Su M, Zhou Y, Zang Y, Li J, Chen Y, Fang Y, Zhang X, Lu W.
    Eur J Med Chem; 2015 May 05; 95():127-35. PubMed ID: 25805446
    [Abstract] [Full Text] [Related]

  • 10. NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
    Das Mukherjee D, Kumar NM, Tantak MP, Datta S, Ghosh Dastidar D, Kumar D, Chakrabarti G.
    Biochim Biophys Acta Mol Cell Res; 2020 Oct 05; 1867(10):118762. PubMed ID: 32502617
    [Abstract] [Full Text] [Related]

  • 11. The microtubule depolymerizing agent naphthazarin induces both apoptosis and autophagy in A549 lung cancer cells.
    Acharya BR, Bhattacharyya S, Choudhury D, Chakrabarti G.
    Apoptosis; 2011 Sep 05; 16(9):924-39. PubMed ID: 21667044
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, anticancer activity and molecular docking studies of N-deacetylthiocolchicine and 4-iodo-N-deacetylthiocolchicine derivatives.
    Klejborowska G, Urbaniak A, Maj E, Wietrzyk J, Moshari M, Preto J, Tuszynski JA, Chambers TC, Huczyński A.
    Bioorg Med Chem; 2021 Feb 15; 32():116014. PubMed ID: 33465696
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation.
    Fournier-Dit-Chabert J, Vinader V, Santos AR, Redondo-Horcajo M, Dreneau A, Basak R, Cosentino L, Marston G, Abdel-Rahman H, Loadman PM, Shnyder SD, Díaz JF, Barasoain I, Falconer RA, Pors K.
    Bioorg Med Chem Lett; 2012 Dec 15; 22(24):7693-6. PubMed ID: 23103097
    [Abstract] [Full Text] [Related]

  • 14. The Cellular Uptake and Apoptotic Efficiency of Colchicine is Correlated with Downregulation of MMP-9 mRNA Expression in SW480 Colon Cancer Cells.
    Ozmen N, Kaya-Sezginer E, Bakar-Ates F.
    Anticancer Agents Med Chem; 2018 Dec 15; 18(13):1927-1933. PubMed ID: 30129419
    [Abstract] [Full Text] [Related]

  • 15. CJK-7, a Novel Flavonoid from Paulownia tomentosa Triggers Cell Death Cascades in HCT-116 Human Colon Carcinoma Cells via Redox Signaling.
    Singh MP, Park KH, Khaket TP, Kang SC.
    Anticancer Agents Med Chem; 2018 Dec 15; 18(3):428-437. PubMed ID: 29076434
    [Abstract] [Full Text] [Related]

  • 16. Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site.
    Gagné-Boulet M, Bouzriba C, Chavez Alvarez AC, Fortin S.
    Eur J Med Chem; 2021 Mar 05; 213():113136. PubMed ID: 33472119
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological evaluation of novel non-racemic indole-containing allocolchicinoids.
    Shchegravina ES, Maleev AA, Ignatov SK, Gracheva IA, Stein A, Schmalz HG, Gavryushin AE, Zubareva AA, Svirshchevskaya EV, Fedorov AY.
    Eur J Med Chem; 2017 Dec 01; 141():51-60. PubMed ID: 29028531
    [Abstract] [Full Text] [Related]

  • 18. Autophagy, cell death and sustained senescence arrest in B16/F10 melanoma cells and HCT-116 colon carcinoma cells in response to the novel microtubule poison, JG-03-14.
    Biggers JW, Nguyen T, Di X, Gupton JT, Henderson SC, Emery SM, Alotaibi M, White KL, Brown R, Almenara J, Gewirtz DA.
    Cancer Chemother Pharmacol; 2013 Feb 01; 71(2):441-55. PubMed ID: 23178952
    [Abstract] [Full Text] [Related]

  • 19. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities.
    Zhang H, Fang X, Meng Q, Mao Y, Xu Y, Fan T, An J, Huang Z.
    Eur J Med Chem; 2018 Sep 05; 157():380-396. PubMed ID: 30099258
    [Abstract] [Full Text] [Related]

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