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314 related items for PubMed ID: 26930604
21. Electrophysiological properties of HBI-3000: a new antiarrhythmic agent with multiple-channel blocking properties in human ventricular myocytes. Guo D, Liu Q, Liu T, Elliott G, Gingras M, Kowey PR, Yan GX. J Cardiovasc Pharmacol; 2011 Jan; 57(1):79-85. PubMed ID: 20980921 [Abstract] [Full Text] [Related]
22. Transmural dispersion of repolarization as a preclinical marker of drug-induced proarrhythmia. Said TH, Wilson LD, Jeyaraj D, Fossa AA, Rosenbaum DS. J Cardiovasc Pharmacol; 2012 Aug; 60(2):165-71. PubMed ID: 22561361 [Abstract] [Full Text] [Related]
23. Drug-induced torsade de pointes: from molecular biology to bedside. Tamargo J. Jpn J Pharmacol; 2000 May; 83(1):1-19. PubMed ID: 10887935 [Abstract] [Full Text] [Related]
24. Theoretical investigation of action potential duration dependence on extracellular Ca2+ in human cardiomyocytes. Grandi E, Pasqualini FS, Pes C, Corsi C, Zaza A, Severi S. J Mol Cell Cardiol; 2009 Mar; 46(3):332-42. PubMed ID: 19121322 [Abstract] [Full Text] [Related]
25. Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes. Guo J, Massaeli H, Li W, Xu J, Luo T, Shaw J, Kirshenbaum LA, Zhang S. J Pharmacol Exp Ther; 2007 Jun; 321(3):911-20. PubMed ID: 17377062 [Abstract] [Full Text] [Related]
26. Availability of human induced pluripotent stem cell-derived cardiomyocytes in assessment of drug potential for QT prolongation. Nozaki Y, Honda Y, Tsujimoto S, Watanabe H, Kunimatsu T, Funabashi H. Toxicol Appl Pharmacol; 2014 Jul 01; 278(1):72-7. PubMed ID: 24742750 [Abstract] [Full Text] [Related]
27. In-vitro experimental models for the risk assessment of antibiotic-induced QT prolongation. Lu HR, Vlaminckx E, Van de Water A, Rohrbacher J, Hermans A, Gallacher DJ. Eur J Pharmacol; 2006 Dec 28; 553(1-3):229-39. PubMed ID: 17054943 [Abstract] [Full Text] [Related]
28. Antagonism by ranolazine of the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes. Song Y, Shryock JC, Wu L, Belardinelli L. J Cardiovasc Pharmacol; 2004 Aug 28; 44(2):192-9. PubMed ID: 15243300 [Abstract] [Full Text] [Related]
29. Balance Between Rapid Delayed Rectifier K+ Current and Late Na+ Current on Ventricular Repolarization: An Effective Antiarrhythmic Target? Hegyi B, Chen-Izu Y, Izu LT, Rajamani S, Belardinelli L, Bers DM, Bányász T. Circ Arrhythm Electrophysiol; 2020 Apr 28; 13(4):e008130. PubMed ID: 32202931 [Abstract] [Full Text] [Related]
30. Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes. Nalos L, Varkevisser R, Jonsson MK, Houtman MJ, Beekman JD, van der Nagel R, Thomsen MB, Duker G, Sartipy P, de Boer TP, Peschar M, Rook MB, van Veen TA, van der Heyden MA, Vos MA. Br J Pharmacol; 2012 Jan 28; 165(2):467-78. PubMed ID: 21718297 [Abstract] [Full Text] [Related]
31. Selective inhibition of physiological late Na+ current stabilizes ventricular repolarization. El-Bizri N, Li CH, Liu GX, Rajamani S, Belardinelli L. Am J Physiol Heart Circ Physiol; 2018 Feb 01; 314(2):H236-H245. PubMed ID: 28971840 [Abstract] [Full Text] [Related]
32. Acceleration-induced action potential prolongation and early afterdepolarizations. Burashnikov A, Antzelevitch C. J Cardiovasc Electrophysiol; 1998 Sep 01; 9(9):934-48. PubMed ID: 9786074 [Abstract] [Full Text] [Related]
33. Preclinical cardiac safety assessment of pharmaceutical compounds using an integrated systems-based computer model of the heart. Bottino D, Penland RC, stamps A, Traebert M, Dumotier B, Georgiva A, Helmlinger G, Lett GS. Prog Biophys Mol Biol; 2006 Sep 01; 90(1-3):414-43. PubMed ID: 16321428 [Abstract] [Full Text] [Related]
35. Action potential experiments complete hERG assay and QT-interval measurements in cardiac preclinical studies. Ducroq J, Printemps R, Guilbot S, Gardette J, Salvetat C, Le Grand M. J Pharmacol Toxicol Methods; 2007 Jul 01; 56(2):159-70. PubMed ID: 17604185 [Abstract] [Full Text] [Related]
36. Assessment of the ion channel-blocking profile of the novel combined ion channel blocker AZD1305 and its proarrhythmic potential versus dofetilide in the methoxamine-sensitized rabbit in vivo. Carlsson L, Andersson B, Linhardt G, Löfberg L. J Cardiovasc Pharmacol; 2009 Jul 01; 54(1):82-9. PubMed ID: 19528812 [Abstract] [Full Text] [Related]
37. Electrophysiologic effects of SB-237376: a new antiarrhythmic compound with dual potassium and calcium channel blocking action. Xu X, Yan GX, Wu Y, Liu T, Kowey PR. J Cardiovasc Pharmacol; 2003 Mar 01; 41(3):414-21. PubMed ID: 12605020 [Abstract] [Full Text] [Related]
38. Modulation of the late sodium current by ATX-II and ranolazine affects the reverse use-dependence and proarrhythmic liability of IKr blockade. Jia S, Lian J, Guo D, Xue X, Patel C, Yang L, Yuan Z, Ma A, Yan GX. Br J Pharmacol; 2011 Sep 01; 164(2):308-16. PubMed ID: 21182492 [Abstract] [Full Text] [Related]
39. Two components of delayed rectifier K+ current in heart: molecular basis, functional diversity, and contribution to repolarization. Cheng JH, Kodama I. Acta Pharmacol Sin; 2004 Feb 01; 25(2):137-45. PubMed ID: 14769199 [Abstract] [Full Text] [Related]