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Journal Abstract Search

211 related items for PubMed ID: 26959013

  • 1. Computational Study on New Natural Compound Inhibitors of Pyruvate Dehydrogenase Kinases.
    Zhou X, Yu S, Su J, Sun L.
    Int J Mol Sci; 2016 Mar 04; 17(3):340. PubMed ID: 26959013
    [Abstract] [Full Text] [Related]

  • 2. Discovery of novel pyruvate dehydrogenase kinases inhibitors by screening of an in-house small molecule library for anti-lung cancer therapeutics.
    Guo F, Zhao S, Li X.
    Bioorg Med Chem Lett; 2019 Jan 15; 29(2):291-296. PubMed ID: 30470491
    [Abstract] [Full Text] [Related]

  • 3. Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?
    Zhang W, Zhang SL, Hu X, Tam KY.
    Int J Biol Sci; 2015 Jan 15; 11(12):1390-400. PubMed ID: 26681918
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  • 4. Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy.
    Anwar S, Shamsi A, Mohammad T, Islam A, Hassan MI.
    Biochim Biophys Acta Rev Cancer; 2021 Aug 15; 1876(1):188568. PubMed ID: 34023419
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  • 6. Nematode pyruvate dehydrogenase kinases: role of the C-terminus in binding to the dihydrolipoyl transacetylase core of the pyruvate dehydrogenase complex.
    Chen W, Komuniecki PR, Komuniecki R.
    Biochem J; 1999 Apr 01; 339 ( Pt 1)(Pt 1):103-9. PubMed ID: 10085233
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of Pyruvate Dehydrogenase Kinase as a Therapeutic Strategy against Cancer.
    Sradhanjali S, Reddy MM.
    Curr Top Med Chem; 2018 Apr 01; 18(6):444-453. PubMed ID: 29788890
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  • 10. High-throughput screening of novel pyruvate dehydrogenase kinases inhibitors and biological evaluation of their in vitro and in vivo antiproliferative activity.
    Wu DM, Wang YJ, Fan SH, Zhang ZF, Shan Q, Lu J, Chen GQ, Zheng YL.
    Eur J Med Chem; 2019 Feb 15; 164():252-262. PubMed ID: 30597326
    [Abstract] [Full Text] [Related]

  • 11. Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket.
    Tso SC, Qi X, Gui WJ, Wu CY, Chuang JL, Wernstedt-Asterholm I, Morlock LK, Owens KR, Scherer PE, Williams NS, Tambar UK, Wynn RM, Chuang DT.
    J Biol Chem; 2014 Feb 14; 289(7):4432-43. PubMed ID: 24356970
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  • 12. Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors.
    Tso SC, Lou M, Wu CY, Gui WJ, Chuang JL, Morlock LK, Williams NS, Wynn RM, Qi X, Chuang DT.
    J Med Chem; 2017 Feb 09; 60(3):1142-1150. PubMed ID: 28085286
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  • 14. Identification and evaluation of bioactive natural products as potential inhibitors of human microtubule affinity-regulating kinase 4 (MARK4).
    Mohammad T, Khan FI, Lobb KA, Islam A, Ahmad F, Hassan MI.
    J Biomol Struct Dyn; 2019 Apr 09; 37(7):1813-1829. PubMed ID: 29683402
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  • 15. Recent advances in pyruvate dehydrogenase kinase inhibitors: Structures, inhibitory mechanisms and biological activities.
    Li Y, Xie Z, Lei X, Yang X, Huang S, Yuan W, Deng X, Wang Z, Tang G.
    Bioorg Chem; 2024 Mar 09; 144():107160. PubMed ID: 38301426
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  • 16. Synthesis of chromeno[3,4-b]indoles as Lamellarin D analogues: a novel DYRK1A inhibitor class.
    Neagoie C, Vedrenne E, Buron F, Mérour JY, Rosca S, Bourg S, Lozach O, Meijer L, Baldeyrou B, Lansiaux A, Routier S.
    Eur J Med Chem; 2012 Mar 09; 49():379-96. PubMed ID: 22305342
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  • 17. R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase.
    Korotchkina LG, Sidhu S, Patel MS.
    Free Radic Res; 2004 Oct 09; 38(10):1083-92. PubMed ID: 15512796
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  • 19. The discovery of Polo-like kinase 4 inhibitors: design and optimization of spiro[cyclopropane-1,3'[3H]indol]-2'(1'H).ones as orally bioavailable antitumor agents.
    Sampson PB, Liu Y, Patel NK, Feher M, Forrest B, Li SW, Edwards L, Laufer R, Lang Y, Ban F, Awrey DE, Mao G, Plotnikova O, Leung G, Hodgson R, Mason JM, Wei X, Kiarash R, Green E, Qiu W, Chirgadze NY, Mak TW, Pan G, Pauls HW.
    J Med Chem; 2015 Jan 08; 58(1):130-46. PubMed ID: 24867403
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