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124 related items for PubMed ID: 26960749

  • 1. Dovitinib Acts As a Novel Radiosensitizer in Hepatocellular Carcinoma by Targeting SHP-1/STAT3 Signaling.
    Huang CY, Tai WT, Wu SY, Shih CT, Chen MH, Tsai MH, Kuo CW, Shiau CW, Hung MH, Chen KF.
    Int J Radiat Oncol Biol Phys; 2016 Jun 01; 95(2):761-71. PubMed ID: 26960749
    [Abstract] [Full Text] [Related]

  • 2. Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3.
    Tai WT, Cheng AL, Shiau CW, Liu CY, Ko CH, Lin MW, Chen PJ, Chen KF.
    Mol Cancer Ther; 2012 Feb 01; 11(2):452-63. PubMed ID: 22180308
    [Abstract] [Full Text] [Related]

  • 3. Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3.
    Chen KF, Chen HL, Liu CY, Tai WT, Ichikawa K, Chen PJ, Cheng AL.
    Biochem Pharmacol; 2012 Mar 15; 83(6):769-77. PubMed ID: 22230479
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  • 6. Nintedanib (BIBF-1120) inhibits hepatocellular carcinoma growth independent of angiokinase activity.
    Tai WT, Shiau CW, Li YS, Chang CW, Huang JW, Hsueh TT, Yu HC, Chen KF.
    J Hepatol; 2014 Jul 15; 61(1):89-97. PubMed ID: 24657398
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  • 8. A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation.
    Chen KF, Su JC, Liu CY, Huang JW, Chen KC, Chen WL, Tai WT, Shiau CW.
    Cancer Lett; 2012 Aug 01; 321(1):27-35. PubMed ID: 22465052
    [Abstract] [Full Text] [Related]

  • 9. Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma.
    Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF.
    J Hepatol; 2011 Nov 01; 55(5):1041-8. PubMed ID: 21354226
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  • 11. SHP-1 is a negative regulator of epithelial-mesenchymal transition in hepatocellular carcinoma.
    Fan LC, Shiau CW, Tai WT, Hung MH, Chu PY, Hsieh FS, Lin H, Yu HC, Chen KF.
    Oncogene; 2015 Oct 08; 34(41):5252-63. PubMed ID: 25619838
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  • 12. Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.
    Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G.
    J Cell Physiol; 2012 May 08; 227(5):2184-95. PubMed ID: 21792937
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  • 13. ZnAs@SiO2 nanoparticles as a potential anti-tumor drug for targeting stemness and epithelial-mesenchymal transition in hepatocellular carcinoma via SHP-1/JAK2/STAT3 signaling.
    Huang Y, Zhou B, Luo H, Mao J, Huang Y, Zhang K, Mei C, Yan Y, Jin H, Gao J, Su Z, Pang P, Li D, Shan H.
    Theranostics; 2019 May 08; 9(15):4391-4408. PubMed ID: 31285768
    [Abstract] [Full Text] [Related]

  • 14. Dovitinib demonstrates antitumor and antimetastatic activities in xenograft models of hepatocellular carcinoma.
    Huynh H, Chow PK, Tai WM, Choo SP, Chung AY, Ong HS, Soo KC, Ong R, Linnartz R, Shi MM.
    J Hepatol; 2012 Mar 08; 56(3):595-601. PubMed ID: 22027573
    [Abstract] [Full Text] [Related]

  • 15. A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy.
    Chao TI, Tai WT, Hung MH, Tsai MH, Chen MH, Chang MJ, Shiau CW, Chen KF.
    Cancer Lett; 2016 Feb 28; 371(2):205-13. PubMed ID: 26679051
    [Abstract] [Full Text] [Related]

  • 16. RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells.
    Su JC, Chiang HC, Tseng PH, Tai WT, Hsu CY, Li YS, Huang JW, Ko CH, Lin MW, Chu PY, Liu CY, Chen KF, Shiau CW.
    Carcinogenesis; 2014 Dec 28; 35(12):2807-14. PubMed ID: 25322871
    [Abstract] [Full Text] [Related]

  • 17. Sorafenib enhances radiation-induced apoptosis in hepatocellular carcinoma by inhibiting STAT3.
    Huang CY, Lin CS, Tai WT, Hsieh CY, Shiau CW, Cheng AL, Chen KF.
    Int J Radiat Oncol Biol Phys; 2013 Jul 01; 86(3):456-62. PubMed ID: 23474115
    [Abstract] [Full Text] [Related]

  • 18. Dovitinib preferentially targets endothelial cells rather than cancer cells for the inhibition of hepatocellular carcinoma growth and metastasis.
    Chen ZY, Shi M, Peng LX, Wei W, Li XJ, Guo ZX, Li SH, Zhong C, Qian CN, Guo RP.
    J Transl Med; 2012 Dec 10; 10():245. PubMed ID: 23228017
    [Abstract] [Full Text] [Related]

  • 19. Sonic Hedgehog inhibition as a strategy to augment radiosensitivity of hepatocellular carcinoma.
    Tsai CL, Hsu FM, Tzen KY, Liu WL, Cheng AL, Cheng JC.
    J Gastroenterol Hepatol; 2015 Aug 10; 30(8):1317-24. PubMed ID: 25682950
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  • 20. SC-60, a dimer-based sorafenib derivative, shows a better anti-hepatocellular carcinoma effect than sorafenib in a preclinical hepatocellular carcinoma model.
    Tai WT, Shiau CW, Li YS, Chen YL, Chu PY, Huang JW, Hsu CY, Hsu YC, Chen PJ, Chen KF.
    Mol Cancer Ther; 2014 Jan 10; 13(1):27-36. PubMed ID: 24275147
    [Abstract] [Full Text] [Related]

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