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Journal Abstract Search

290 related items for PubMed ID: 26963494

  • 1. Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer.
    Zou P, Xia Y, Ji J, Chen W, Zhang J, Chen X, Rajamanickam V, Chen G, Wang Z, Chen L, Wang Y, Yang S, Liang G.
    Cancer Lett; 2016 May 28; 375(1):114-126. PubMed ID: 26963494
    [Abstract] [Full Text] [Related]

  • 2. EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells.
    Zou P, Xia Y, Chen W, Chen X, Ying S, Feng Z, Chen T, Ye Q, Wang Z, Qiu C, Yang S, Liang G.
    Oncotarget; 2016 Apr 05; 7(14):18050-64. PubMed ID: 26919110
    [Abstract] [Full Text] [Related]

  • 3. Piperlongumine potentiates the antitumor efficacy of oxaliplatin through ROS induction in gastric cancer cells.
    Zhang P, Shi L, Zhang T, Hong L, He W, Cao P, Shen X, Zheng P, Xia Y, Zou P.
    Cell Oncol (Dordr); 2019 Dec 05; 42(6):847-860. PubMed ID: 31493144
    [Abstract] [Full Text] [Related]

  • 4. Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation.
    Chen W, Zou P, Zhao Z, Weng Q, Chen X, Ying S, Ye Q, Wang Z, Ji J, Liang G.
    Oncotarget; 2016 Mar 29; 7(13):16593-609. PubMed ID: 26919094
    [Abstract] [Full Text] [Related]

  • 5. Auranofin induces apoptosis by ROS-mediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancer.
    Zou P, Chen M, Ji J, Chen W, Chen X, Ying S, Zhang J, Zhang Z, Liu Z, Yang S, Liang G.
    Oncotarget; 2015 Nov 03; 6(34):36505-21. PubMed ID: 26431378
    [Abstract] [Full Text] [Related]

  • 6. Potent inhibition of gastric cancer cells by a natural compound via inhibiting TrxR1 activity and activating ROS-mediated p38 MAPK pathway.
    He W, Cao P, Xia Y, Hong L, Zhang T, Shen X, Zheng P, Shen H, Zhao Y, Zou P.
    Free Radic Res; 2019 Jan 03; 53(1):104-114. PubMed ID: 30668191
    [Abstract] [Full Text] [Related]

  • 7. Piperlongumine, a Novel TrxR1 Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cells by ROS-Mediated ER Stress.
    Zhang Q, Chen W, Lv X, Weng Q, Chen M, Cui R, Liang G, Ji J.
    Front Pharmacol; 2019 Jan 03; 10():1180. PubMed ID: 31680962
    [Abstract] [Full Text] [Related]

  • 8. Curcuminoid WZ35 synergize with cisplatin by inducing ROS production and inhibiting TrxR1 activity in gastric cancer cells.
    He W, Xia Y, Cao P, Hong L, Zhang T, Shen X, Zheng P, Shen H, Liang G, Zou P.
    J Exp Clin Cancer Res; 2019 May 21; 38(1):207. PubMed ID: 31113439
    [Abstract] [Full Text] [Related]

  • 9. Piperlongumine induces gastric cancer cell apoptosis and G2/M cell cycle arrest both in vitro and in vivo.
    Duan C, Zhang B, Deng C, Cao Y, Zhou F, Wu L, Chen M, Shen S, Xu G, Zhang S, Duan G, Yan H, Zou X.
    Tumour Biol; 2016 Aug 21; 37(8):10793-804. PubMed ID: 26874726
    [Abstract] [Full Text] [Related]

  • 10. Curcuminoid B63 induces ROS-mediated paraptosis-like cell death by targeting TrxR1 in gastric cells.
    Chen X, Chen X, Zhang X, Wang L, Cao P, Rajamanickam V, Wu C, Zhou H, Cai Y, Liang G, Wang Y.
    Redox Biol; 2019 Feb 21; 21():101061. PubMed ID: 30590310
    [Abstract] [Full Text] [Related]

  • 11. Selenocysteine induces apoptosis in human glioma cells: evidence for TrxR1-targeted inhibition and signaling crosstalk.
    Fan CD, Fu XY, Zhang ZY, Cao MZ, Sun JY, Yang MF, Fu XT, Zhao SJ, Shao LR, Zhang HF, Yang XY, Sun BL.
    Sci Rep; 2017 Jul 25; 7(1):6465. PubMed ID: 28743999
    [Abstract] [Full Text] [Related]

  • 12. Ethaselen synergizes with oxaliplatin in tumor growth inhibition by inducing ROS production and inhibiting TrxR1 activity in gastric cancer.
    Zhang H, Wu J, Yuan J, Li H, Zhang Y, Wu W, Chen W, Wang C, Meng S, Chen S, Huo M, He Y, Zhang C.
    J Exp Clin Cancer Res; 2021 Aug 19; 40(1):260. PubMed ID: 34412665
    [Abstract] [Full Text] [Related]

  • 13. Gambogic acid induces apoptosis in hepatocellular carcinoma SMMC-7721 cells by targeting cytosolic thioredoxin reductase.
    Duan D, Zhang B, Yao J, Liu Y, Sun J, Ge C, Peng S, Fang J.
    Free Radic Biol Med; 2014 Apr 19; 69():15-25. PubMed ID: 24407164
    [Abstract] [Full Text] [Related]

  • 14. Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer.
    Zhuge W, Chen R, Vladimir K, Dong X, Zia K, Sun X, Dai X, Bao M, Shen X, Liang G.
    Cancer Lett; 2018 Jan 01; 412():46-58. PubMed ID: 29037867
    [Abstract] [Full Text] [Related]

  • 15. Curcuminoid WZ26, a TrxR1 inhibitor, effectively inhibits colon cancer cell growth and enhances cisplatin-induced cell death through the induction of ROS.
    Zhang T, Zheng P, Shen X, Shao R, Wang B, Shen H, Zhang J, Xia Y, Zou P.
    Free Radic Biol Med; 2019 Sep 01; 141():93-102. PubMed ID: 31176737
    [Abstract] [Full Text] [Related]

  • 16. Withaferin A, a natural thioredoxin reductase 1 (TrxR1) inhibitor, synergistically enhances the antitumor efficacy of sorafenib through ROS-mediated ER stress and DNA damage in hepatocellular carcinoma cells.
    Chen X, Zhu N, Wu Y, Zhang Y, Zhang Y, Jin K, Zhou Z, Chen G, Wang J.
    Phytomedicine; 2024 Jun 01; 128():155317. PubMed ID: 38537439
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis, and biological evaluation of a novel indoleamine 2,3-dioxigenase 1 (IDO1) and thioredoxin reductase (TrxR) dual inhibitor.
    Fan QZ, Zhou J, Zhu YB, He LJ, Miao DD, Zhang SP, Liu XP, Zhang C.
    Bioorg Chem; 2020 Dec 01; 105():104401. PubMed ID: 33113415
    [Abstract] [Full Text] [Related]

  • 18. Alantolactone promotes ER stress-mediated apoptosis by inhibition of TrxR1 in triple-negative breast cancer cell lines and in a mouse model.
    Yin C, Dai X, Huang X, Zhu W, Chen X, Zhou Q, Wang C, Zhao C, Zou P, Liang G, Rajamanickam V, Wang O, Zhang X, Cui R.
    J Cell Mol Med; 2019 Mar 01; 23(3):2194-2206. PubMed ID: 30609207
    [Abstract] [Full Text] [Related]

  • 19. Isobavachalcone Induces ROS-Mediated Apoptosis via Targeting Thioredoxin Reductase 1 in Human Prostate Cancer PC-3 Cells.
    Li K, Zheng Q, Chen X, Wang Y, Wang D, Wang J.
    Oxid Med Cell Longev; 2018 Mar 01; 2018():1915828. PubMed ID: 30410640
    [Abstract] [Full Text] [Related]

  • 20. Inducing ubiquitination and degradation of TrxR1 protein by LW-216 promotes apoptosis in non-small cell lung cancer via triggering ROS production.
    Wang R, Zhong L, Wang T, Sun T, Yang J, Liu X, Wu Y, Guo Q, Gao Y, Zhao K.
    Neoplasia; 2024 Jul 01; 53():101004. PubMed ID: 38733769
    [Abstract] [Full Text] [Related]

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