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165 related items for PubMed ID: 27001594

  • 1. Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity.
    Lukashevich OV, Cherepanova NA, Jurkovska RZ, Jeltsch A, Gromova ES.
    BMC Biochem; 2016 Mar 22; 17():7. PubMed ID: 27001594
    [Abstract] [Full Text] [Related]

  • 2. Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase.
    Gowher H, Loutchanwoot P, Vorobjeva O, Handa V, Jurkowska RZ, Jurkowski TP, Jeltsch A.
    J Mol Biol; 2006 Mar 31; 357(3):928-41. PubMed ID: 16472822
    [Abstract] [Full Text] [Related]

  • 3. Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites.
    Gowher H, Jeltsch A.
    J Mol Biol; 2001 Jun 22; 309(5):1201-8. PubMed ID: 11399089
    [Abstract] [Full Text] [Related]

  • 4. The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI.
    Shieh FK, Youngblood B, Reich NO.
    J Mol Biol; 2006 Sep 22; 362(3):516-27. PubMed ID: 16926025
    [Abstract] [Full Text] [Related]

  • 5. Mutational analysis of the CG recognizing DNA methyltransferase SssI: insight into enzyme-DNA interactions.
    Darii MV, Cherepanova NA, Subach OM, Kirsanova OV, Raskó T, Slaska-Kiss K, Kiss A, Deville-Bonne D, Reboud-Ravaux M, Gromova ES.
    Biochim Biophys Acta; 2009 Nov 22; 1794(11):1654-62. PubMed ID: 19654054
    [Abstract] [Full Text] [Related]

  • 6. Catalytic mechanism of DNA-(cytosine-C5)-methyltransferases revisited: covalent intermediate formation is not essential for methyl group transfer by the murine Dnmt3a enzyme.
    Reither S, Li F, Gowher H, Jeltsch A.
    J Mol Biol; 2003 Jun 13; 329(4):675-84. PubMed ID: 12787669
    [Abstract] [Full Text] [Related]

  • 7. Impact of 7,8-dihydro-8-oxoguanine on methylation of the CpG site by Dnmt3a.
    Maltseva DV, Baykov AA, Jeltsch A, Gromova ES.
    Biochemistry; 2009 Feb 17; 48(6):1361-8. PubMed ID: 19161295
    [Abstract] [Full Text] [Related]

  • 8. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.
    Jia D, Jurkowska RZ, Zhang X, Jeltsch A, Cheng X.
    Nature; 2007 Sep 13; 449(7159):248-51. PubMed ID: 17713477
    [Abstract] [Full Text] [Related]

  • 9. De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases.
    Gowher H, Stockdale CJ, Goyal R, Ferreira H, Owen-Hughes T, Jeltsch A.
    Biochemistry; 2005 Jul 26; 44(29):9899-904. PubMed ID: 16026162
    [Abstract] [Full Text] [Related]

  • 10. The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA.
    Fatemi M, Hermann A, Pradhan S, Jeltsch A.
    J Mol Biol; 2001 Jun 22; 309(5):1189-99. PubMed ID: 11399088
    [Abstract] [Full Text] [Related]

  • 11. Structural insight into autoinhibition and histone H3-induced activation of DNMT3A.
    Guo X, Wang L, Li J, Ding Z, Xiao J, Yin X, He S, Shi P, Dong L, Li G, Tian C, Wang J, Cong Y, Xu Y.
    Nature; 2015 Jan 29; 517(7536):640-4. PubMed ID: 25383530
    [Abstract] [Full Text] [Related]

  • 12. AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI.
    Shieh FK, Reich NO.
    J Mol Biol; 2007 Nov 09; 373(5):1157-68. PubMed ID: 17897676
    [Abstract] [Full Text] [Related]

  • 13. Mechanistic Insights into Cytosine-N3 Methylation by DNA Methyltransferase DNMT3A.
    Dukatz M, Requena CE, Emperle M, Hajkova P, Sarkies P, Jeltsch A.
    J Mol Biol; 2019 Aug 09; 431(17):3139-3145. PubMed ID: 31229457
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.
    Sheikhnejad G, Brank A, Christman JK, Goddard A, Alvarez E, Ford H, Marquez VE, Marasco CJ, Sufrin JR, O'gara M, Cheng X.
    J Mol Biol; 1999 Feb 05; 285(5):2021-34. PubMed ID: 9925782
    [Abstract] [Full Text] [Related]

  • 15. Functional roles of the conserved aromatic amino acid residues at position 108 (motif IV) and position 196 (motif VIII) in base flipping and catalysis by the N6-adenine DNA methyltransferase from Thermus aquaticus.
    Pues H, Bleimling N, Holz B, Wölcke J, Weinhold E.
    Biochemistry; 1999 Feb 02; 38(5):1426-34. PubMed ID: 9931007
    [Abstract] [Full Text] [Related]

  • 16. Mechanism of CpG DNA methyltransferases M.SssI and Dnmt3a studied by DNA containing 2-aminopurine.
    Cherepanova NA, Minero AS, Rakhimova AR, Gromova ES.
    Nucleosides Nucleotides Nucleic Acids; 2011 Feb 02; 30(7-8):619-31. PubMed ID: 21888552
    [Abstract] [Full Text] [Related]

  • 17. Allosteric activator domain of maintenance human DNA (cytosine-5) methyltransferase and its role in methylation spreading.
    Pradhan S, Estève PO.
    Biochemistry; 2003 May 13; 42(18):5321-32. PubMed ID: 12731873
    [Abstract] [Full Text] [Related]

  • 18. Identification of a second DNA binding site in human DNA methyltransferase 3A by substrate inhibition and domain deletion.
    Purdy MM, Holz-Schietinger C, Reich NO.
    Arch Biochem Biophys; 2010 Jun 01; 498(1):13-22. PubMed ID: 20227382
    [Abstract] [Full Text] [Related]

  • 19. Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity.
    Siddique AN, Nunna S, Rajavelu A, Zhang Y, Jurkowska RZ, Reinhardt R, Rots MG, Ragozin S, Jurkowski TP, Jeltsch A.
    J Mol Biol; 2013 Feb 08; 425(3):479-91. PubMed ID: 23220192
    [Abstract] [Full Text] [Related]

  • 20. Characterization of DNA-binding activity in the N-terminal domain of the DNA methyltransferase Dnmt3a.
    Suetake I, Mishima Y, Kimura H, Lee YH, Goto Y, Takeshima H, Ikegami T, Tajima S.
    Biochem J; 2011 Jul 01; 437(1):141-8. PubMed ID: 21510846
    [Abstract] [Full Text] [Related]

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