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Journal Abstract Search

1176 related items for PubMed ID: 27002158

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  • 3. Nicotinamide Adenine Dinucleotide Precursor Supplementation Modulates Neurite Complexity and Survival in Motor Neurons from Amyotrophic Lateral Sclerosis Models.
    Hamilton HL, Akther M, Anis S, Colwell CB, Vargas MR, Pehar M.
    Antioxid Redox Signal; 2024 Sep; 41(7-9):573-589. PubMed ID: 38504592
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  • 4. Mitochondria-targeted catalase reverts the neurotoxicity of hSOD1G⁹³A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice.
    Pehar M, Beeson G, Beeson CC, Johnson JA, Vargas MR.
    PLoS One; 2014 Sep; 9(7):e103438. PubMed ID: 25054289
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  • 5. Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1.
    Harlan BA, Pehar M, Killoy KM, Vargas MR.
    FASEB J; 2019 Jun; 33(6):7084-7091. PubMed ID: 30841754
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  • 8. Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis.
    Miquel E, Cassina A, Martínez-Palma L, Bolatto C, Trías E, Gandelman M, Radi R, Barbeito L, Cassina P.
    PLoS One; 2012 Jun; 7(4):e34776. PubMed ID: 22509356
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  • 11. NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients.
    Johann S, Heitzer M, Kanagaratnam M, Goswami A, Rizo T, Weis J, Troost D, Beyer C.
    Glia; 2015 Dec; 63(12):2260-73. PubMed ID: 26200799
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  • 15. Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.
    Cassina P, Cassina A, Pehar M, Castellanos R, Gandelman M, de León A, Robinson KM, Mason RP, Beckman JS, Barbeito L, Radi R.
    J Neurosci; 2008 Apr 16; 28(16):4115-22. PubMed ID: 18417691
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  • 16. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D, Haasdijk ED, Grashorn JA, Hawkins R, van Duijn W, Verspaget HW, London J, Holstege JC.
    Neurobiol Dis; 2000 Dec 16; 7(6 Pt B):623-43. PubMed ID: 11114261
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  • 17. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis.
    Parone PA, Da Cruz S, Han JS, McAlonis-Downes M, Vetto AP, Lee SK, Tseng E, Cleveland DW.
    J Neurosci; 2013 Mar 13; 33(11):4657-71. PubMed ID: 23486940
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  • 18. Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis.
    Urushitani M, Kurisu J, Tsukita K, Takahashi R.
    J Neurochem; 2002 Dec 13; 83(5):1030-42. PubMed ID: 12437574
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  • 19. Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis.
    Pehar M, Cassina P, Vargas MR, Castellanos R, Viera L, Beckman JS, Estévez AG, Barbeito L.
    J Neurochem; 2004 Apr 13; 89(2):464-73. PubMed ID: 15056289
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  • 20. Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment.
    Park JH, Jang HR, Lee IY, Oh HK, Choi EJ, Rhim H, Kang S.
    Hum Mol Genet; 2017 Sep 15; 26(18):3615-3629. PubMed ID: 28666328
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