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Journal Abstract Search

463 related items for PubMed ID: 27009949

  • 1. Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.
    Becares M, Pascual-Iglesias A, Nogales A, Sola I, Enjuanes L, Zuñiga S.
    J Virol; 2016 Jun 01; 90(11):5399-5414. PubMed ID: 27009949
    [Abstract] [Full Text] [Related]

  • 2. Murine Hepatitis Virus nsp14 Exoribonuclease Activity Is Required for Resistance to Innate Immunity.
    Case JB, Li Y, Elliott R, Lu X, Graepel KW, Sexton NR, Smith EC, Weiss SR, Denison MR.
    J Virol; 2018 Jan 01; 92(1):. PubMed ID: 29046453
    [Abstract] [Full Text] [Related]

  • 3. The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2.
    Ogando NS, Zevenhoven-Dobbe JC, van der Meer Y, Bredenbeek PJ, Posthuma CC, Snijder EJ.
    J Virol; 2020 Nov 09; 94(23):. PubMed ID: 32938769
    [Abstract] [Full Text] [Related]

  • 4. Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.
    Case JB, Ashbrook AW, Dermody TS, Denison MR.
    J Virol; 2016 Aug 15; 90(16):7248-7256. PubMed ID: 27252528
    [Abstract] [Full Text] [Related]

  • 5. Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses.
    Lu Y, Cai H, Lu M, Ma Y, Li A, Gao Y, Zhou J, Gu H, Li J, Gu J.
    J Virol; 2020 Jul 30; 94(16):. PubMed ID: 32461321
    [Abstract] [Full Text] [Related]

  • 6. N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition.
    Pan R, Kindler E, Cao L, Zhou Y, Zhang Z, Liu Q, Ebert N, Züst R, Sun Y, Gorbalenya AE, Perlman S, Thiel V, Chen Y, Guo D.
    mBio; 2022 Feb 22; 13(1):e0366221. PubMed ID: 35073761
    [Abstract] [Full Text] [Related]

  • 7. Proteolytic Processing of the Coronavirus Replicase Nonstructural Protein 14 Exonuclease Is Not Required for Virus Replication but Alters RNA Synthesis and Viral Fitness.
    Anderson-Daniels J, Gribble J, Denison M.
    J Virol; 2022 Aug 24; 96(16):e0084122. PubMed ID: 35924922
    [Abstract] [Full Text] [Related]

  • 8. Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication.
    Ogando NS, El Kazzi P, Zevenhoven-Dobbe JC, Bontes BW, Decombe A, Posthuma CC, Thiel V, Canard B, Ferron F, Decroly E, Snijder EJ.
    Proc Natl Acad Sci U S A; 2021 Dec 07; 118(49):. PubMed ID: 34845015
    [Abstract] [Full Text] [Related]

  • 9. High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.
    Eckerle LD, Lu X, Sperry SM, Choi L, Denison MR.
    J Virol; 2007 Nov 07; 81(22):12135-44. PubMed ID: 17804504
    [Abstract] [Full Text] [Related]

  • 10. Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity.
    Smith EC, Case JB, Blanc H, Isakov O, Shomron N, Vignuzzi M, Denison MR.
    J Virol; 2015 Jun 07; 89(12):6418-26. PubMed ID: 25855750
    [Abstract] [Full Text] [Related]

  • 11. Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.
    Chen Y, Tao J, Sun Y, Wu A, Su C, Gao G, Cai H, Qiu S, Wu Y, Ahola T, Guo D.
    J Virol; 2013 Jun 07; 87(11):6296-305. PubMed ID: 23536667
    [Abstract] [Full Text] [Related]

  • 12. Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
    Ferron F, Subissi L, Silveira De Morais AT, Le NTT, Sevajol M, Gluais L, Decroly E, Vonrhein C, Bricogne G, Canard B, Imbert I.
    Proc Natl Acad Sci U S A; 2018 Jan 09; 115(2):E162-E171. PubMed ID: 29279395
    [Abstract] [Full Text] [Related]

  • 13. Proofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations.
    Graepel KW, Lu X, Case JB, Sexton NR, Smith EC, Denison MR.
    mBio; 2017 Nov 07; 8(6):. PubMed ID: 29114026
    [Abstract] [Full Text] [Related]

  • 14. Identification of a gamma interferon-activated inhibitor of translation-like RNA motif at the 3' end of the transmissible gastroenteritis coronavirus genome modulating innate immune response.
    Marquez-Jurado S, Nogales A, Zuñiga S, Enjuanes L, Almazán F.
    mBio; 2015 Mar 10; 6(2):e00105. PubMed ID: 25759500
    [Abstract] [Full Text] [Related]

  • 15. Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex.
    Ma Y, Wu L, Shaw N, Gao Y, Wang J, Sun Y, Lou Z, Yan L, Zhang R, Rao Z.
    Proc Natl Acad Sci U S A; 2015 Jul 28; 112(30):9436-41. PubMed ID: 26159422
    [Abstract] [Full Text] [Related]

  • 16. Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity.
    Lin S, Chen H, Chen Z, Yang F, Ye F, Zheng Y, Yang J, Lin X, Sun H, Wang L, Wen A, Dong H, Xiao Q, Deng D, Cao Y, Lu G.
    Nucleic Acids Res; 2021 May 21; 49(9):5382-5392. PubMed ID: 33956156
    [Abstract] [Full Text] [Related]

  • 17. New targets for drug design: importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2.
    Saramago M, Bárria C, Costa VG, Souza CS, Viegas SC, Domingues S, Lousa D, Soares CM, Arraiano CM, Matos RG.
    FEBS J; 2021 Sep 21; 288(17):5130-5147. PubMed ID: 33705595
    [Abstract] [Full Text] [Related]

  • 18. Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase.
    Chen Y, Cai H, Pan J, Xiang N, Tien P, Ahola T, Guo D.
    Proc Natl Acad Sci U S A; 2009 Mar 03; 106(9):3484-9. PubMed ID: 19208801
    [Abstract] [Full Text] [Related]

  • 19. RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex.
    Bouvet M, Imbert I, Subissi L, Gluais L, Canard B, Decroly E.
    Proc Natl Acad Sci U S A; 2012 Jun 12; 109(24):9372-7. PubMed ID: 22635272
    [Abstract] [Full Text] [Related]

  • 20. Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes.
    Bouvet M, Lugari A, Posthuma CC, Zevenhoven JC, Bernard S, Betzi S, Imbert I, Canard B, Guillemot JC, Lécine P, Pfefferle S, Drosten C, Snijder EJ, Decroly E, Morelli X.
    J Biol Chem; 2014 Sep 12; 289(37):25783-96. PubMed ID: 25074927
    [Abstract] [Full Text] [Related]

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