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Journal Abstract Search

189 related items for PubMed ID: 27017541

  • 1. Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1.
    Gryshchenko AA, Tarnavskiy SS, Levchenko KV, Bdzhola VG, Volynets GP, Golub AG, Ruban TP, Vygranenko KV, Lukash LL, Yarmoluk SM.
    Bioorg Med Chem; 2016 May 01; 24(9):2053-9. PubMed ID: 27017541
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and biological evaluation of 3-vinyl-quinoxalin-2(1H)-one derivatives as novel antitumor inhibitors of FGFR1.
    Liu Z, Yu S, Chen D, Shen G, Wang Y, Hou L, Lin D, Zhang J, Ye F.
    Drug Des Devel Ther; 2016 May 01; 10():1489-500. PubMed ID: 27217720
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  • 4. Design, Synthesis and Biological Evaluation of 6-(2,6-Dichloro-3,5-dimethoxyphenyl)-4-substituted-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors.
    Zhang Z, Zhao D, Dai Y, Cheng M, Geng M, Shen J, Ma Y, Ai J, Xiong B.
    Molecules; 2016 Oct 23; 21(10):. PubMed ID: 27782099
    [Abstract] [Full Text] [Related]

  • 5. Identification of apoptosis signal-regulating kinase 1 (ASK1) inhibitors among the derivatives of benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one.
    Starosyla SA, Volynets GP, Lukashov SS, Gorbatiuk OB, Golub AG, Bdzhola VG, Yarmoluk SM.
    Bioorg Med Chem; 2015 May 15; 23(10):2489-97. PubMed ID: 25882527
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  • 8. Discovery of N-(2-phenyl-1H-benzo[d]imidazol-5-yl)quinolin-4-amine derivatives as novel VEGFR-2 kinase inhibitors.
    Shi L, Wu TT, Wang Z, Xue JY, Xu YG.
    Eur J Med Chem; 2014 Sep 12; 84():698-707. PubMed ID: 25064347
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  • 9. Design, Synthesis, and Biological Evaluation of C-2 Substituted 3Hthieno[ 2,3-d]pyrimidin-4-one Derivatives as Novel FGFR1 Inhibitors.
    Guo P, Xie Z, Zhang H, Zhang Z, Han C, Cheng D, Lin D, Zhang Y, Wang X, Guo X, Ye F.
    Med Chem; 2017 Sep 12; 13(8):753-760. PubMed ID: 28641527
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  • 10. Acenaphtho[1,2-b]pyrrole-based selective fibroblast growth factor receptors 1 (FGFR1) inhibitors: design, synthesis, and biological activity.
    Chen Z, Wang X, Zhu W, Cao X, Tong L, Li H, Xie H, Xu Y, Tan S, Kuang D, Ding J, Qian X.
    J Med Chem; 2011 Jun 09; 54(11):3732-45. PubMed ID: 21517068
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  • 12. Design, synthesis and biological evaluation of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives as novel FGFR1 inhibitors for treatment of non-small cell lung cancer.
    Xie Z, Cheng D, Luo L, Shen G, Pan S, Pan Y, Chen B, Wang X, Liu Z, Zhang Y, Ye F.
    J Enzyme Inhib Med Chem; 2018 Dec 09; 33(1):905-919. PubMed ID: 29734851
    [Abstract] [Full Text] [Related]

  • 13. N-(4-{[4-(1H-Benzoimidazol-2-yl)-arylamino]-methyl}-phenyl)-benzamide derivatives as small molecule heparanase inhibitors.
    Xu YJ, Miao HQ, Pan W, Navarro EC, Tonra JR, Mitelman S, Camara MM, Deevi DS, Kiselyov AS, Kussie P, Wong WC, Liu H.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):404-8. PubMed ID: 16246551
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  • 14. Design, synthesis, and biological activity of phenyl-pyrazole derivatives as BCR-ABL kinase inhibitors.
    Hu L, Zheng Y, Li Z, Wang Y, Lv Y, Qin X, Zeng C.
    Bioorg Med Chem; 2015 Jul 01; 23(13):3147-52. PubMed ID: 26022079
    [Abstract] [Full Text] [Related]

  • 15. Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.
    Martin MW, Newcomb J, Nunes JJ, Boucher C, Chai L, Epstein LF, Faust T, Flores S, Gallant P, Gore A, Gu Y, Hsieh F, Huang X, Kim JL, Middleton S, Morgenstern K, Oliveira-dos-Santos A, Patel VF, Powers D, Rose P, Tudor Y, Turci SM, Welcher AA, Zack D, Zhao H, Zhu L, Zhu X, Ghiron C, Ermann M, Johnston D, Saluste CG.
    J Med Chem; 2008 Mar 27; 51(6):1637-48. PubMed ID: 18278858
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  • 16. Design, modification and 3D QSAR studies of novel 2,3-dihydrobenzo[b][1,4]dioxin-containing 4,5-dihydro-1H-pyrazole derivatives as inhibitors of B-Raf kinase.
    Yang YS, Li QS, Sun S, Zhang YB, Wang XL, Zhang F, Tang JF, Zhu HL.
    Bioorg Med Chem; 2012 Oct 15; 20(20):6048-58. PubMed ID: 22985962
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  • 17. 1-[4-(1H-Benzoimidazol-2-yl)-phenyl]-3-[4-(1H-benzoimidazol-2-yl)-phenyl]-urea derivatives as small molecule heparanase inhibitors.
    Pan W, Miao HQ, Xu YJ, Navarro EC, Tonra JR, Corcoran E, Lahiji A, Kussie P, Kiselyov AS, Wong WC, Liu H.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):409-12. PubMed ID: 16246560
    [Abstract] [Full Text] [Related]

  • 18. Structure-activity relationships of 3,4-dihydro-1H-quinazolin-2-one derivatives as potential CDK5 inhibitors.
    Rzasa RM, Kaller MR, Liu G, Magal E, Nguyen TT, Osslund TD, Powers D, Santora VJ, Viswanadhan VN, Wang HL, Xiong X, Zhong W, Norman MH.
    Bioorg Med Chem; 2007 Oct 15; 15(20):6574-95. PubMed ID: 17697781
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and biological evaluation of naphthostyril derivatives as novel protein kinase FGFR1 inhibitors.
    Gryshchenko AA, Levchenko KV, Bdzhola VG, Ruban TP, Lukash LL, Yarmoluk SM.
    J Enzyme Inhib Med Chem; 2015 Feb 15; 30(1):126-32. PubMed ID: 24939105
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, characterization and antimicrobial activity of some novel benzimidazole derivatives.
    Krishnanjaneyulu IS, Saravanan G, Vamsi J, Supriya P, Bhavana JU, Sunil Kumar MV.
    J Adv Pharm Technol Res; 2014 Jan 15; 5(1):21-7. PubMed ID: 24696814
    [Abstract] [Full Text] [Related]

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