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Journal Abstract Search

462 related items for PubMed ID: 27030360

  • 1. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell.
    Hasanpourghadi M, Karthikeyan C, Pandurangan AK, Looi CY, Trivedi P, Kobayashi K, Tanaka K, Wong WF, Mustafa MR.
    J Exp Clin Cancer Res; 2016 Mar 31; 35():58. PubMed ID: 27030360
    [Abstract] [Full Text] [Related]

  • 2. Mechanisms of the anti-tumor activity of Methyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo[d]imidazole-5-carboxylate against breast cancer in vitro and in vivo.
    Hasanpourghadi M, Pandurangan AK, Karthikeyan C, Trivedi P, Mustafa MR.
    Oncotarget; 2017 Apr 25; 8(17):28840-28853. PubMed ID: 28392503
    [Abstract] [Full Text] [Related]

  • 3. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.
    Chung KS, Choi HE, Shin JS, Cho YW, Choi JH, Cho WJ, Lee KT.
    Carcinogenesis; 2013 Aug 25; 34(8):1852-60. PubMed ID: 23615402
    [Abstract] [Full Text] [Related]

  • 4. Methyl 5-[(1H-indol-3-yl)selanyl]-1H-benzoimidazol-2-ylcarbamate (M-24), a novel tubulin inhibitor, causes G2/M arrest and cell apoptosis by disrupting tubulin polymerization in human cervical and breast cancer cells.
    Zuo D, Jiang X, Han M, Shen J, Lang B, Guan Q, Bai Z, Han C, Li Z, Zhang W, Wu Y.
    Toxicol In Vitro; 2017 Aug 25; 42():139-149. PubMed ID: 28412508
    [Abstract] [Full Text] [Related]

  • 5. 3-(3-Hydroxy-4-methoxyphenyl)-4-(3,4,5-trimethoxyphenyl)-1,2,5-selenadiazole (G-1103), a novel combretastatin A-4 analog, induces G2/M arrest and apoptosis by disrupting tubulin polymerization in human cervical HeLa cells and fibrosarcoma HT-1080 cells.
    Zuo D, Guo D, Jiang X, Guan Q, Qi H, Xu J, Li Z, Yang F, Zhang W, Wu Y.
    Chem Biol Interact; 2015 Feb 05; 227():7-17. PubMed ID: 25529822
    [Abstract] [Full Text] [Related]

  • 6. Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines.
    Ling YH, Jiang JD, Holland JF, Perez-Soler R.
    Mol Pharmacol; 2002 Sep 05; 62(3):529-38. PubMed ID: 12181429
    [Abstract] [Full Text] [Related]

  • 7. Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.
    Ho CH, Hsu JL, Liu SP, Hsu LC, Chang WL, Chao CC, Guh JH.
    Prostate; 2015 Sep 05; 75(13):1454-66. PubMed ID: 26180030
    [Abstract] [Full Text] [Related]

  • 8. A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma.
    Dai X, Wang L, Deivasigamni A, Looi CY, Karthikeyan C, Trivedi P, Chinnathambi A, Alharbi SA, Arfuso F, Dharmarajan A, Goh BC, Hui KM, Kumar AP, Mustafa MR, Sethi G.
    Oncotarget; 2017 Feb 21; 8(8):12831-12842. PubMed ID: 28086233
    [Abstract] [Full Text] [Related]

  • 9. Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
    Lu PH, Kung FL, Kuo SC, Chueh SC, Guh JH.
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Dec 21; 374(3):223-33. PubMed ID: 17102938
    [Abstract] [Full Text] [Related]

  • 10. A molecular understanding of D-homoestrone-induced G2/M cell cycle arrest in HeLa human cervical carcinoma cells.
    Minorics R, Bózsity N, Molnár J, Wölfling J, Mernyák E, Schneider G, Ocsovszki I, Zupkó I.
    J Cell Mol Med; 2015 Oct 21; 19(10):2365-74. PubMed ID: 26228523
    [Abstract] [Full Text] [Related]

  • 11. Activation of autophagy by stress-activated signals as a cellular self-defense mechanism against the cytotoxic effects of MBIC in human breast cancer cells in vitro.
    Hasanpourghadi M, Majid NA, Mustafa MR.
    Biochem Pharmacol; 2018 Jun 21; 152():174-186. PubMed ID: 29608909
    [Abstract] [Full Text] [Related]

  • 12. Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells – a critical role of Cdk1 in mitotic entry.
    Chang WL, Yu CC, Chen CS, Guh JH.
    Biochem Pharmacol; 2015 Mar 01; 94(1):12-21. PubMed ID: 25615907
    [Abstract] [Full Text] [Related]

  • 13. 2-APCAs, the Novel Microtubule Targeting Agents Active Against Distinct Cancer Cell Lines.
    Boichuk S, Galembikova A, Bikinieva F, Dunaev P, Aukhadieva A, Syuzov K, Zykova S, Igidov N, Ksenofontov A, Bocharov P.
    Molecules; 2021 Jan 25; 26(3):. PubMed ID: 33503939
    [Abstract] [Full Text] [Related]

  • 14. Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents.
    Wang RC, Chen X, Parissenti AM, Joy AA, Tuszynski J, Brindley DN, Wang Z.
    PLoS One; 2017 Jan 25; 12(8):e0182400. PubMed ID: 28787019
    [Abstract] [Full Text] [Related]

  • 15. CXI-benzo-84 reversibly binds to tubulin at colchicine site and induces apoptosis in cancer cells.
    Rai A, Gupta TK, Kini S, Kunwar A, Surolia A, Panda D.
    Biochem Pharmacol; 2013 Aug 01; 86(3):378-91. PubMed ID: 23747346
    [Abstract] [Full Text] [Related]

  • 16. NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
    Das Mukherjee D, Kumar NM, Tantak MP, Datta S, Ghosh Dastidar D, Kumar D, Chakrabarti G.
    Biochim Biophys Acta Mol Cell Res; 2020 Oct 01; 1867(10):118762. PubMed ID: 32502617
    [Abstract] [Full Text] [Related]

  • 17. Mechanism of antiproliferative action of a new d-secoestrone-triazole derivative in cervical cancer cells and its effect on cancer cell motility.
    Bózsity N, Minorics R, Szabó J, Mernyák E, Schneider G, Wölfling J, Wang HC, Wu CC, Ocsovszki I, Zupkó I.
    J Steroid Biochem Mol Biol; 2017 Jan 01; 165(Pt B):247-257. PubMed ID: 27363663
    [Abstract] [Full Text] [Related]

  • 18. Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells.
    Qu Z, Zou X, Zhang X, Sheng J, Wang Y, Wang J, Wang C, Ji Y.
    Mol Med Rep; 2016 Feb 01; 13(2):1336-44. PubMed ID: 26677104
    [Abstract] [Full Text] [Related]

  • 19. 2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase.
    Chang WL, Chang CS, Chiang PC, Ho YF, Liu JF, Chang KW, Guh JH.
    Br J Pharmacol; 2010 Aug 01; 160(7):1677-89. PubMed ID: 20649571
    [Abstract] [Full Text] [Related]

  • 20. A comprehensive assessment of a new series of 5',6'-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs).
    Riu F, Sanna L, Ibba R, Piras S, Bordoni V, Scorciapino MA, Lai M, Sestito S, Bagella L, Carta A.
    Eur J Med Chem; 2021 Oct 15; 222():113590. PubMed ID: 34139625
    [Abstract] [Full Text] [Related]

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