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Journal Abstract Search

155 related items for PubMed ID: 27043518

  • 1. Synthesis and Structure-Activity Relationship Analysis of 5-HT₇ Receptor Antagonists: Piperazin-1-yl Substituted Unfused Heterobiaryls.
    Strekowski L, Sączewski J, Raux EA, Fernando NT, Klenc J, Paranjpe S, Raszkiewicz A, Blake AL, Ehalt AJ, Barnes S, Baranowski TC, Sullivan SM, Satała G, Bojarski AJ.
    Molecules; 2016 Mar 31; 21(4):433. PubMed ID: 27043518
    [Abstract] [Full Text] [Related]

  • 2. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Niso M, Perrone R, Tortorella V.
    J Med Chem; 2004 Dec 16; 47(26):6616-24. PubMed ID: 15588097
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  • 3. Sulfonamides with the N-alkyl-N'-dialkylguanidine moiety as 5-HT7 receptor ligands.
    Zajdel P, Subra G, Verdie P, Gabzdyl E, Bojarski AJ, Duszyńska B, Martinez J, Pawłowski M.
    Bioorg Med Chem Lett; 2009 Aug 15; 19(16):4827-31. PubMed ID: 19560916
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  • 4. Synthesis and structure-activity relationships of a new model of arylpiperazines. Study of the 5-HT(1a)/alpha(1)-adrenergic receptor affinity by classical hansch analysis, artificial neural networks, and computational simulation of ligand recognition.
    López-Rodríguez ML, Morcillo MJ, Fernández E, Rosado ML, Pardo L, Schaper K.
    J Med Chem; 2001 Jan 18; 44(2):198-207. PubMed ID: 11170629
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  • 5. Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
    Hirokawa Y, Fujiwara I, Suzuki K, Harada H, Yoshikawa T, Yoshida N, Kato S.
    J Med Chem; 2003 Feb 27; 46(5):702-15. PubMed ID: 12593651
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  • 6. Design and synthesis of new homo and hetero bis-piperazinyl-1-propanone derivatives as 5-HT7R selective ligands over 5-HT1AR.
    Intagliata S, Modica MN, Pittalà V, Salerno L, Siracusa MA, Cagnotto A, Salmona M, Romeo G.
    Bioorg Med Chem Lett; 2016 Aug 15; 26(16):4052-6. PubMed ID: 27396505
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  • 7. Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo.
    Lacivita E, Patarnello D, Stroth N, Caroli A, Niso M, Contino M, De Giorgio P, Di Pilato P, Colabufo NA, Berardi F, Perrone R, Svenningsson P, Hedlund PB, Leopoldo M.
    J Med Chem; 2012 Jul 26; 55(14):6375-80. PubMed ID: 22738316
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  • 9. Synthesis and SAR of 3- and 4-substituted quinolin-2-ones: discovery of mixed 5-HT(1B)/5-HT(2A) receptor antagonists.
    McCort G, Hoornaert C, Aletru M, Denys C, Duclos O, Cadilhac C, Guilpain E, Dellac G, Janiak P, Galzin AM, Delahaye M, Guilbert F, O'Connor S.
    Bioorg Med Chem; 2001 Aug 26; 9(8):2129-37. PubMed ID: 11504649
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  • 11. Modification of the structure of 4, 6-disubstituted 2-(4-alkyl-1-piperazinyl)pyridines: synthesis and their 5-HT2A receptor activity.
    Paluchowska MH, Bojarski AJ, Bugno R, Charakchieva-Minol S, Wesołowska A.
    Arch Pharm (Weinheim); 2003 Apr 26; 336(2):104-10. PubMed ID: 12761763
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT₁A and 5-HT₇ receptor ligands.
    Modica MN, Intagliata S, Pittalà V, Salerno L, Siracusa MA, Cagnotto A, Salmona M, Romeo G.
    Bioorg Med Chem Lett; 2015 Apr 01; 25(7):1427-30. PubMed ID: 25759032
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  • 13. Aryl biphenyl-3-ylmethylpiperazines as 5-HT7 receptor antagonists.
    Kim J, Kim Y, Tae J, Yeom M, Moon B, Huang XP, Roth BL, Lee K, Rhim H, Choo IH, Chong Y, Keum G, Nam G, Choo H.
    ChemMedChem; 2013 Nov 01; 8(11):1855-64. PubMed ID: 24039134
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  • 14. Synthesis and structure-activity relationship (SAR) of (5,7-disubstituted 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidin-2-yl)-methylamines as potent serotonin 5-HT(6) receptor (5-HT(6)R) antagonists.
    Ivachtchenko AV, Golovina ES, Kadieva MG, Kysil VM, Mitkin OD, Tkachenko SE, Okun IM.
    J Med Chem; 2011 Dec 08; 54(23):8161-73. PubMed ID: 22029285
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  • 18. Extended N-Arylsulfonylindoles as 5-HT₆ Receptor Antagonists: Design, Synthesis & Biological Evaluation.
    Vera G, Lagos CF, Almendras S, Hebel D, Flores F, Valle-Corvalán G, Pessoa-Mahana CD, Mella-Raipán J, Montecinos R, Recabarren-Gajardo G.
    Molecules; 2016 Aug 16; 21(8):. PubMed ID: 27537868
    [Abstract] [Full Text] [Related]

  • 19. Synthesis by microwave irradiation and binding properties of novel 5-HT(1A) receptor ligands.
    Caliendo G, Fiorino F, Perissutti E, Severino B, Gessi S, Cattabriga E, Borea PA, Santagada V.
    Eur J Med Chem; 2001 Aug 16; 36(11-12):873-86. PubMed ID: 11755230
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  • 20. Synthesis and evaluation of 5-HT(2A) and 5-HT(2C) receptor binding affinities of novel pyrimidine derivatives.
    Bózsing D, Simonek I, Simig G, Jakóczi I, Gacsályi I, Lévay G, Tihanyi K, Schmidt E.
    Bioorg Med Chem Lett; 2002 Nov 04; 12(21):3097-9. PubMed ID: 12372510
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