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Journal Abstract Search

197 related items for PubMed ID: 27045471

  • 1. NAD(P)H:Quinone Oxidoreductase-1 Expression Sensitizes Malignant Melanoma Cells to the HSP90 Inhibitor 17-AAG.
    Kasai S, Arakawa N, Okubo A, Shigeeda W, Yasuhira S, Masuda T, Akasaka T, Shibazaki M, Maesawa C.
    PLoS One; 2016; 11(4):e0153181. PubMed ID: 27045471
    [Abstract] [Full Text] [Related]

  • 2. Acquired resistance to 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin) in glioblastoma cells.
    Gaspar N, Sharp SY, Pacey S, Jones C, Walton M, Vassal G, Eccles S, Pearson A, Workman P.
    Cancer Res; 2009 Mar 01; 69(5):1966-75. PubMed ID: 19244114
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  • 3. Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition.
    Guo W, Reigan P, Siegel D, Zirrolli J, Gustafson D, Ross D.
    Cancer Res; 2005 Nov 01; 65(21):10006-15. PubMed ID: 16267026
    [Abstract] [Full Text] [Related]

  • 4. Use of NQO1 status as a selective biomarker for oesophageal squamous cell carcinomas with greater sensitivity to 17-AAG.
    Hadley KE, Hendricks DT.
    BMC Cancer; 2014 May 15; 14():334. PubMed ID: 24886060
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  • 5. The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo.
    Douglas M, Lim AR, Porter JR, West K, Pink MM, Ge J, Wylie AA, Tibbits TT, Biggs K, Curtis M, Palombella VJ, Adams J, Fritz CC, Normant E.
    Mol Cancer Ther; 2009 Dec 15; 8(12):3369-78. PubMed ID: 19952119
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.
    Torrente L, Prieto-Farigua N, Falzone A, Elkins CM, Boothman DA, Haura EB, DeNicola GM.
    Redox Biol; 2020 Feb 15; 30():101440. PubMed ID: 32007910
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  • 7. The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.
    Ui T, Morishima K, Saito S, Sakuma Y, Fujii H, Hosoya Y, Ishikawa S, Aburatani H, Fukayama M, Niki T, Yasuda Y.
    Oncol Rep; 2014 Feb 15; 31(2):619-24. PubMed ID: 24317439
    [Abstract] [Full Text] [Related]

  • 8. HSP90 inhibition induces cytotoxicity via down-regulation of Rad51 expression and DNA repair capacity in non-small cell lung cancer cells.
    Ko JC, Chen HJ, Huang YC, Tseng SC, Weng SH, Wo TY, Huang YJ, Chiu HC, Tsai MS, Chiou RY, Lin YW.
    Regul Toxicol Pharmacol; 2012 Dec 15; 64(3):415-24. PubMed ID: 23069143
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  • 10. Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells.
    Ohba S, Hirose Y, Yoshida K, Yazaki T, Kawase T.
    J Neurosurg; 2010 Jan 15; 112(1):33-42. PubMed ID: 19408974
    [Abstract] [Full Text] [Related]

  • 11. Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells.
    Zhan L, Zhang H, Zhang Q, Woods CG, Chen Y, Xue P, Dong J, Tokar EJ, Xu Y, Hou Y, Fu J, Yarborough K, Wang A, Qu W, Waalkes MP, Andersen ME, Pi J.
    Free Radic Biol Med; 2012 Aug 15; 53(4):758-68. PubMed ID: 22684020
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  • 12. Inhibition of thymidine phosphorylase expression by using an HSP90 inhibitor potentiates the cytotoxic effect of cisplatin in non-small-cell lung cancer cells.
    Weng SH, Tseng SC, Huang YC, Chen HJ, Lin YW.
    Biochem Pharmacol; 2012 Jul 01; 84(1):126-36. PubMed ID: 22480737
    [Abstract] [Full Text] [Related]

  • 13. NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones.
    Siegel D, Yan C, Ross D.
    Biochem Pharmacol; 2012 Apr 15; 83(8):1033-40. PubMed ID: 22209713
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  • 16. Modulation of Nrf2/Keap1 system by Wasabi 6-methylthiohexyl isothiocyanate in ARE-mediated NQO1 expression.
    Korenori Y, Tanigawa S, Kumamoto T, Qin S, Daikoku Y, Miyamori K, Nagai M, Hou DX.
    Mol Nutr Food Res; 2013 May 15; 57(5):854-64. PubMed ID: 23390006
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