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Journal Abstract Search

271 related items for PubMed ID: 2704738

  • 1. Trypanothione is the primary target for arsenical drugs against African trypanosomes.
    Fairlamb AH, Henderson GB, Cerami A.
    Proc Natl Acad Sci U S A; 1989 Apr; 86(8):2607-11. PubMed ID: 2704738
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  • 2. Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism.
    Fairlamb AH, Carter NS, Cunningham M, Smith K.
    Mol Biochem Parasitol; 1992 Jul; 53(1-2):213-22. PubMed ID: 1501641
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  • 4. Differential sensitivity of Trypanosoma brucei rhodesiense isolates to in vitro lysis by arsenicals.
    Yarlett N, Goldberg B, Nathan HC, Garofalo J, Bacchi CJ.
    Exp Parasitol; 1991 Feb; 72(2):205-15. PubMed ID: 1849084
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  • 6. Inhibiting effects of spermidine derivatives on Trypanosoma cruzi trypanothione reductase.
    O'Sullivan MC, Dalrymple DM, Zhou Q.
    J Enzyme Inhib; 1996 Oct; 11(2):97-114. PubMed ID: 9204399
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  • 10. Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei.
    Shahi SK, Krauth-Siegel RL, Clayton CE.
    Mol Microbiol; 2002 Mar; 43(5):1129-38. PubMed ID: 11918801
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  • 11. A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes.
    Ebersoll S, Bogacz M, Günter LM, Dick TP, Krauth-Siegel RL.
    Elife; 2020 Jan 31; 9():. PubMed ID: 32003744
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  • 12. Glyoxalase II of African trypanosomes is trypanothione-dependent.
    Irsch T, Krauth-Siegel RL.
    J Biol Chem; 2004 May 21; 279(21):22209-17. PubMed ID: 14976196
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  • 13. Properties of trypanothione synthetase from Trypanosoma brucei.
    Oza SL, Ariyanayagam MR, Aitcheson N, Fairlamb AH.
    Mol Biochem Parasitol; 2003 Sep 21; 131(1):25-33. PubMed ID: 12967709
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  • 14. Mutational analysis of parasite trypanothione reductase: acquisition of glutathione reductase activity in a triple mutant.
    Sullivan FX, Sobolov SB, Bradley M, Walsh CT.
    Biochemistry; 1991 Mar 19; 30(11):2761-7. PubMed ID: 2007114
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  • 15. Enzymes of the trypanothione metabolism as targets for antitrypanosomal drug development.
    Schmidt A, Krauth-Siegel RL.
    Curr Top Med Chem; 2002 Nov 19; 2(11):1239-59. PubMed ID: 12171583
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  • 16. Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei.
    Zimmermann S, Oufir M, Leroux A, Krauth-Siegel RL, Becker K, Kaiser M, Brun R, Hamburger M, Adams M.
    Bioorg Med Chem; 2013 Nov 15; 21(22):7202-9. PubMed ID: 24080104
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  • 17. Trypanothione dependent peroxide metabolism in Crithidia fasciculata and Trypanosoma brucei.
    Henderson GB, Fairlamb AH, Cerami A.
    Mol Biochem Parasitol; 1987 May 15; 24(1):39-45. PubMed ID: 3614271
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  • 18. Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase.
    Duyzend MH, Clark CT, Simmons SL, Johnson WB, Larson AM, Leconte AM, Wills AW, Ginder-Vogel M, Wilhelm AK, Czechowicz JA, Alberg DG.
    J Enzyme Inhib Med Chem; 2012 Dec 15; 27(6):784-94. PubMed ID: 22085139
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  • 19. Antitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism.
    König J, Wyllie S, Wells G, Stevens MF, Wyatt PG, Fairlamb AH.
    J Biol Chem; 2011 Mar 11; 286(10):8523-8533. PubMed ID: 21212280
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  • 20. Potent trypanocidal curcumin analogs bearing a monoenone linker motif act on trypanosoma brucei by forming an adduct with trypanothione.
    Alkhaldi AA, Creek DJ, Ibrahim H, Kim DH, Quashie NB, Burgess KE, Changtam C, Barrett MP, Suksamrarn A, de Koning HP.
    Mol Pharmacol; 2015 Mar 11; 87(3):451-64. PubMed ID: 25527638
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