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Journal Abstract Search

271 related items for PubMed ID: 2704738

  • 21. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
    Chan C, Yin H, Garforth J, McKie JH, Jaouhari R, Speers P, Douglas KT, Rock PJ, Yardley V, Croft SL, Fairlamb AH.
    J Med Chem; 1998 Jan 15; 41(2):148-56. PubMed ID: 9457238
    [Abstract] [Full Text] [Related]

  • 22. Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism.
    Krauth-Siegel RL, Comini MA.
    Biochim Biophys Acta; 2008 Nov 15; 1780(11):1236-48. PubMed ID: 18395526
    [Abstract] [Full Text] [Related]

  • 23. The synthesis and inhibitory activity of dethiotrypanothione and analogues against trypanothione reductase.
    Czechowicz JA, Wilhelm AK, Spalding MD, Larson AM, Engel LK, Alberg DG.
    J Org Chem; 2007 May 11; 72(10):3689-93. PubMed ID: 17439174
    [Abstract] [Full Text] [Related]

  • 24. Glutathionylation of trypanosomal thiol redox proteins.
    Melchers J, Dirdjaja N, Ruppert T, Krauth-Siegel RL.
    J Biol Chem; 2007 Mar 23; 282(12):8678-94. PubMed ID: 17242409
    [Abstract] [Full Text] [Related]

  • 25. Trypanothione reductase from Trypanosoma cruzi. Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds.
    Jockers-Scherübl MC, Schirmer RH, Krauth-Siegel RL.
    Eur J Biochem; 1989 Mar 15; 180(2):267-72. PubMed ID: 2647489
    [Abstract] [Full Text] [Related]

  • 26. Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents.
    Li Z, Fennie MW, Ganem B, Hancock MT, Kobaslija M, Rattendi D, Bacchi CJ, O'Sullivan MC.
    Bioorg Med Chem Lett; 2001 Jan 22; 11(2):251-4. PubMed ID: 11206471
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  • 28. Trypanothione efficiently intercepts nitric oxide as a harmless iron complex in trypanosomatid parasites.
    Bocedi A, Dawood KF, Fabrini R, Federici G, Gradoni L, Pedersen JZ, Ricci G.
    FASEB J; 2010 Apr 22; 24(4):1035-42. PubMed ID: 19952282
    [Abstract] [Full Text] [Related]

  • 29. Glyoxalase II does not support methylglyoxal detoxification but serves as a general trypanothione thioesterase in African trypanosomes.
    Wendler A, Irsch T, Rabbani N, Thornalley PJ, Krauth-Siegel RL.
    Mol Biochem Parasitol; 2009 Jan 22; 163(1):19-27. PubMed ID: 18848584
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  • 31. Redox enzyme engineering: conversion of human glutathione reductase into a trypanothione reductase.
    Bradley M, Bücheler US, Walsh CT.
    Biochemistry; 1991 Jun 25; 30(25):6124-7. PubMed ID: 2059620
    [Abstract] [Full Text] [Related]

  • 32. Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids.
    Fairlamb AH, Blackburn P, Ulrich P, Chait BT, Cerami A.
    Science; 1985 Mar 22; 227(4693):1485-7. PubMed ID: 3883489
    [Abstract] [Full Text] [Related]

  • 33. Ovothiol and trypanothione as antioxidants in trypanosomatids.
    Ariyanayagam MR, Fairlamb AH.
    Mol Biochem Parasitol; 2001 Jul 22; 115(2):189-98. PubMed ID: 11420105
    [Abstract] [Full Text] [Related]

  • 34. Biosynthesis of the trypanosomatid metabolite trypanothione: purification and characterization of trypanothione synthetase from Crithidia fasciculata.
    Henderson GB, Yamaguchi M, Novoa L, Fairlamb AH, Cerami A.
    Biochemistry; 1990 Apr 24; 29(16):3924-9. PubMed ID: 2354163
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  • 36. The interaction of arsenical drugs with dihydrolipoamide and dihydrolipoamide dehydrogenase from arsenical resistant and sensitive strains of Trypanosoma brucei brucei.
    Fairlamb AH, Smith K, Hunter KJ.
    Mol Biochem Parasitol; 1992 Jul 24; 53(1-2):223-31. PubMed ID: 1501642
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  • 38. The role of Trypanosoma brucei MRPA in melarsoprol susceptibility.
    Alibu VP, Richter C, Voncken F, Marti G, Shahi S, Renggli CK, Seebeck T, Brun R, Clayton C.
    Mol Biochem Parasitol; 2006 Mar 24; 146(1):38-44. PubMed ID: 16343658
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  • 40. Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress.
    Krieger S, Schwarz W, Ariyanayagam MR, Fairlamb AH, Krauth-Siegel RL, Clayton C.
    Mol Microbiol; 2000 Feb 24; 35(3):542-52. PubMed ID: 10672177
    [Abstract] [Full Text] [Related]

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