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996 related items for PubMed ID: 27056669

  • 1. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane.
    O'Neill KL, Huang K, Zhang J, Chen Y, Luo X.
    Genes Dev; 2016 Apr 15; 30(8):973-88. PubMed ID: 27056669
    [Abstract] [Full Text] [Related]

  • 2. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J, Huang K, O'Neill KL, Pang X, Luo X.
    Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874
    [Abstract] [Full Text] [Related]

  • 3. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
    Huang K, O'Neill KL, Li J, Zhou W, Han N, Pang X, Wu W, Struble L, Borgstahl G, Liu Z, Zhang L, Luo X.
    Cell Res; 2019 Nov 16; 29(11):942-952. PubMed ID: 31551537
    [Abstract] [Full Text] [Related]

  • 4. MOMP in the absence of BH3-only proteins.
    García Sáez AJ, Villunger A.
    Genes Dev; 2016 Apr 15; 30(8):878-80. PubMed ID: 27083995
    [Abstract] [Full Text] [Related]

  • 5. Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.
    Uren RT, Dewson G, Chen L, Coyne SC, Huang DC, Adams JM, Kluck RM.
    J Cell Biol; 2007 Apr 23; 177(2):277-87. PubMed ID: 17452531
    [Abstract] [Full Text] [Related]

  • 6. Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.
    Zhai D, Jin C, Huang Z, Satterthwait AC, Reed JC.
    J Biol Chem; 2008 Apr 11; 283(15):9580-6. PubMed ID: 18178565
    [Abstract] [Full Text] [Related]

  • 7. Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.
    Lindqvist LM, Heinlein M, Huang DC, Vaux DL.
    Proc Natl Acad Sci U S A; 2014 Jun 10; 111(23):8512-7. PubMed ID: 24912196
    [Abstract] [Full Text] [Related]

  • 8. In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.
    Senft D, Weber A, Saathoff F, Berking C, Heppt MV, Kammerbauer C, Rothenfusser S, Kellner S, Kurgyis Z, Besch R, Häcker G.
    Cell Death Dis; 2015 Nov 26; 6(11):e1996. PubMed ID: 26610208
    [Abstract] [Full Text] [Related]

  • 9. BCL-2 proteins and apoptosis: Recent insights and unknowns.
    Edlich F.
    Biochem Biophys Res Commun; 2018 May 27; 500(1):26-34. PubMed ID: 28676391
    [Abstract] [Full Text] [Related]

  • 10. Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.
    Gillissen B, Essmann F, Hemmati PG, Richter A, Richter A, Oztop I, Chinnadurai G, Dörken B, Daniel PT.
    J Cell Biol; 2007 Nov 19; 179(4):701-15. PubMed ID: 18025305
    [Abstract] [Full Text] [Related]

  • 11. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2015 Oct 19; 17(10):1270-81. PubMed ID: 26344567
    [Abstract] [Full Text] [Related]

  • 12. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Müer A, Overkamp T, Gillissen B, Richter A, Pretzsch T, Milojkovic A, Dörken B, Daniel PT, Hemmati P.
    J Biol Chem; 2012 May 18; 287(21):17343-17352. PubMed ID: 22354970
    [Abstract] [Full Text] [Related]

  • 13. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C, Anwari K, Ninnis RL, Brouwer J, O'Hely M, Evangelista M, Hinds MG, Czabotar PE, Lee EF, Fairlie WD, Dewson G, Kluck RM.
    Cell Death Dis; 2015 Apr 23; 6(4):e1735. PubMed ID: 25906158
    [Abstract] [Full Text] [Related]

  • 14. MCL-1 inhibits BAX in the absence of MCL-1/BAX Interaction.
    Germain M, Milburn J, Duronio V.
    J Biol Chem; 2008 Mar 07; 283(10):6384-92. PubMed ID: 18089567
    [Abstract] [Full Text] [Related]

  • 15. MCL-1ES induces MCL-1L-dependent BAX- and BAK-independent mitochondrial apoptosis.
    Kim JH, Bae J.
    PLoS One; 2013 Mar 07; 8(11):e79626. PubMed ID: 24260268
    [Abstract] [Full Text] [Related]

  • 16. Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins.
    Goodall KJ, Finch-Edmondson ML, van Vuuren J, Yeoh GC, Gentle IE, Vince JE, Ekert PG, Vaux DL, Callus BA.
    PLoS One; 2016 Mar 07; 11(11):e0164003. PubMed ID: 27806040
    [Abstract] [Full Text] [Related]

  • 17. Pro-apoptotic complexes of BAX and BAK on the outer mitochondrial membrane.
    Wolf P, Schoeniger A, Edlich F.
    Biochim Biophys Acta Mol Cell Res; 2022 Oct 07; 1869(10):119317. PubMed ID: 35752202
    [Abstract] [Full Text] [Related]

  • 18. BH3-only proteins Noxa, Bik, Bmf, and Bid activate Bax and Bak indirectly when studied in yeast model.
    Gérecová G, Kopanicová J, Jaká P, Běhalová L, Juhásová B, Bhatia-Kiššová I, Forte M, Polčic P, Mentel M.
    FEMS Yeast Res; 2013 Dec 07; 13(8):747-54. PubMed ID: 23991648
    [Abstract] [Full Text] [Related]

  • 19. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2006 Dec 07; 8(12):1348-58. PubMed ID: 17115033
    [Abstract] [Full Text] [Related]

  • 20. Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L).
    Lindenboim L, Blacher E, Borner C, Stein R.
    Cell Death Differ; 2010 Feb 07; 17(2):346-59. PubMed ID: 19816507
    [Abstract] [Full Text] [Related]

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