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Journal Abstract Search

378 related items for PubMed ID: 27081696

  • 1. Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer.
    Hong SH, Eun JW, Choi SK, Shen Q, Choi WS, Han JW, Nam SW, You JS.
    Oncotarget; 2016 May 31; 7(22):32628-40. PubMed ID: 27081696
    [Abstract] [Full Text] [Related]

  • 2. Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expression.
    Li GQ, Guo WZ, Zhang Y, Seng JJ, Zhang HP, Ma XX, Zhang G, Li J, Yan B, Tang HW, Li SS, Wang LD, Zhang SJ.
    Oncotarget; 2016 Jan 19; 7(3):2462-74. PubMed ID: 26575167
    [Abstract] [Full Text] [Related]

  • 3. JQ1, an inhibitor of the epigenetic reader BRD4, suppresses the bidirectional MYC-AP4 axis via multiple mechanisms.
    Choi SK, Hong SH, Kim HS, Shin CY, Nam SW, Choi WS, Han JW, You JS.
    Oncol Rep; 2016 Feb 19; 35(2):1186-94. PubMed ID: 26573731
    [Abstract] [Full Text] [Related]

  • 4. BRD4 inhibition suppresses cell growth, migration and invasion of salivary adenoid cystic carcinoma.
    Wang L, Wu X, Wang R, Yang C, Li Z, Wang C, Zhang F, Yang P.
    Biol Res; 2017 May 25; 50(1):19. PubMed ID: 28545522
    [Abstract] [Full Text] [Related]

  • 5. BRD4 promotes tumor growth and epithelial-mesenchymal transition in hepatocellular carcinoma.
    Zhang P, Dong Z, Cai J, Zhang C, Shen Z, Ke A, Gao D, Fan J, Shi G.
    Int J Immunopathol Pharmacol; 2015 Mar 25; 28(1):36-44. PubMed ID: 25816404
    [Abstract] [Full Text] [Related]

  • 6. The bromodomain inhibitor JQ1 up-regulates the long non-coding RNA MALAT1 in cultured human hepatic carcinoma cells.
    Choi HI, An GY, Yoo E, Baek M, Binas B, Chai JC, Lee YS, Jung KH, Chai YG.
    Sci Rep; 2022 May 11; 12(1):7779. PubMed ID: 35546353
    [Abstract] [Full Text] [Related]

  • 7. Targeting BRD4 proteins suppresses the growth of NSCLC through downregulation of eIF4E expression.
    Gao Z, Yuan T, Zhou X, Ni P, Sun G, Li P, Cheng Z, Wang X.
    Cancer Biol Ther; 2018 May 04; 19(5):407-415. PubMed ID: 29333921
    [Abstract] [Full Text] [Related]

  • 8. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
    Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR.
    Nature; 2011 Aug 03; 478(7370):524-8. PubMed ID: 21814200
    [Abstract] [Full Text] [Related]

  • 9. Bromodomain protein BRD4 promotes cell proliferation in skin squamous cell carcinoma.
    Xiang T, Bai JY, She C, Yu DJ, Zhou XZ, Zhao TL.
    Cell Signal; 2018 Jan 03; 42():106-113. PubMed ID: 29050985
    [Abstract] [Full Text] [Related]

  • 10. miR-214/199a/199a* cluster levels predict poor survival in hepatocellular carcinoma through interference with cell-cycle regulators.
    Wang P, Chen S, Fang H, Wu X, Chen D, Peng L, Gao Z, Xie C.
    Oncotarget; 2016 Jan 05; 7(1):929-45. PubMed ID: 26498144
    [Abstract] [Full Text] [Related]

  • 11. Combined inhibition of BET proteins and class I HDACs synergistically induces apoptosis in urothelial carcinoma cell lines.
    Hölscher AS, Schulz WA, Pinkerneil M, Niegisch G, Hoffmann MJ.
    Clin Epigenetics; 2018 Jan 05; 10():1. PubMed ID: 29312470
    [Abstract] [Full Text] [Related]

  • 12. JQ1 and PI3K inhibition synergistically reduce salivary adenoid cystic carcinoma malignancy by targeting the c-Myc and EGFR signaling pathways.
    Liu X, Wu H, Huang P, Zhang F.
    J Oral Pathol Med; 2019 Jan 05; 48(1):43-51. PubMed ID: 30269363
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of BRD4 suppresses tumor growth in prostate cancer via the enhancement of FOXO1 expression.
    Tan Y, Wang L, Du Y, Liu X, Chen Z, Weng X, Guo J, Chen H, Wang M, Wang X.
    Int J Oncol; 2018 Dec 05; 53(6):2503-2517. PubMed ID: 30272279
    [Abstract] [Full Text] [Related]

  • 14. microRNA-608 inhibits human hepatocellular carcinoma cell proliferation via targeting the BET family protein BRD4.
    He L, Meng D, Zhang SH, Zhang Y, Deng Z, Kong LB.
    Biochem Biophys Res Commun; 2018 Jul 02; 501(4):1060-1067. PubMed ID: 29777702
    [Abstract] [Full Text] [Related]

  • 15. JQ1, a small molecule inhibitor of BRD4, suppresses cell growth and invasion in oral squamous cell carcinoma.
    Wang L, Wu X, Huang P, Lv Z, Qi Y, Wei X, Yang P, Zhang F.
    Oncol Rep; 2016 Oct 02; 36(4):1989-96. PubMed ID: 27573714
    [Abstract] [Full Text] [Related]

  • 16. SOX9 is controlled by the BRD4 inhibitor JQ1 via multiple regulation mechanisms.
    Hong SH, You JS.
    Biochem Biophys Res Commun; 2019 Apr 16; 511(4):746-752. PubMed ID: 30833074
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of BRD4 triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells.
    Xu JL, Yuan YJ, Lv J, Qi D, Wu MD, Lan J, Liu SN, Yang Y, Zhai J, Jiang HM.
    J Cell Mol Med; 2020 Nov 16; 24(22):13036-13045. PubMed ID: 32954665
    [Abstract] [Full Text] [Related]

  • 18. Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma.
    Song S, Li Y, Xu Y, Ma L, Pool Pizzi M, Jin J, Scott AW, Huo L, Wang Y, Lee JH, Bhutani MS, Weston B, Shanbhag ND, Johnson RL, Ajani JA.
    Mol Oncol; 2020 Jun 16; 14(6):1410-1426. PubMed ID: 32175692
    [Abstract] [Full Text] [Related]

  • 19. Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
    Zhou X, Fan LX, Peters DJ, Trudel M, Bradner JE, Li X.
    Hum Mol Genet; 2015 Jul 15; 24(14):3982-93. PubMed ID: 25877301
    [Abstract] [Full Text] [Related]

  • 20. BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries.
    Wang B, Zhang M, Takayama T, Shi X, Roenneburg DA, Kent KC, Guo LW.
    EBioMedicine; 2015 Nov 15; 2(11):1650-61. PubMed ID: 26870791
    [Abstract] [Full Text] [Related]

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