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460 related items for PubMed ID: 27084536

  • 1. Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-κB signaling and IL-8 expression.
    Ashour AE, Ahmed AF, Kumar A, Zoheir KM, Aboul-Soud MA, Ahmad SF, Attia SM, Abd-Allah AR, Cheryan VT, Rishi AK.
    Mol Cell Biochem; 2016 May; 416(1-2):141-55. PubMed ID: 27084536
    [Abstract] [Full Text] [Related]

  • 2. Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis.
    Ashour AE, Abd-Allah AR, Korashy HM, Attia SM, Alzahrani AZ, Saquib Q, Bakheet SA, Abdel-Hamied HE, Jamal S, Rishi AK.
    Mol Cell Biochem; 2014 Apr; 389(1-2):85-98. PubMed ID: 24399465
    [Abstract] [Full Text] [Related]

  • 3. Molecular targeting of Akt by thymoquinone promotes G(1) arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells.
    Rajput S, Kumar BN, Dey KK, Pal I, Parekh A, Mandal M.
    Life Sci; 2013 Nov 13; 93(21):783-90. PubMed ID: 24044882
    [Abstract] [Full Text] [Related]

  • 4. Rosmarinic acid sensitizes cell death through suppression of TNF-alpha-induced NF-kappaB activation and ROS generation in human leukemia U937 cells.
    Moon DO, Kim MO, Lee JD, Choi YH, Kim GY.
    Cancer Lett; 2010 Feb 28; 288(2):183-91. PubMed ID: 19619938
    [Abstract] [Full Text] [Related]

  • 5. Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells.
    Roepke M, Diestel A, Bajbouj K, Walluscheck D, Schonfeld P, Roessner A, Schneider-Stock R, Gali-Muhtasib H.
    Cancer Biol Ther; 2007 Feb 28; 6(2):160-9. PubMed ID: 17218778
    [Abstract] [Full Text] [Related]

  • 6. Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase.
    Kundu J, Choi BY, Jeong CH, Kundu JK, Chun KS.
    Oncol Rep; 2014 Aug 28; 32(2):821-8. PubMed ID: 24890449
    [Abstract] [Full Text] [Related]

  • 7. RRR-α-tocopheryl succinate induces apoptosis in human gastric cancer cells via the NF-κB signaling pathway.
    Sun Y, Zhao Y, Hou L, Zhang X, Zhang Z, Wu K.
    Oncol Rep; 2014 Sep 28; 32(3):1243-8. PubMed ID: 24970592
    [Abstract] [Full Text] [Related]

  • 8. Pronounced transcriptional regulation of apoptotic and TNF-NF-kappa-B signaling genes during the course of thymoquinone mediated apoptosis in HeLa cells.
    Sakalar C, Yuruk M, Kaya T, Aytekin M, Kuk S, Canatan H.
    Mol Cell Biochem; 2013 Nov 28; 383(1-2):243-51. PubMed ID: 23943306
    [Abstract] [Full Text] [Related]

  • 9. Thymoquinone enhances cisplatin-response through direct tumor effects in a syngeneic mouse model of ovarian cancer.
    Wilson AJ, Saskowski J, Barham W, Yull F, Khabele D.
    J Ovarian Res; 2015 Jul 28; 8():46. PubMed ID: 26215403
    [Abstract] [Full Text] [Related]

  • 10. Thymoquinone induces oxidative stress-mediated apoptosis through downregulation of Jak2/STAT3 signaling pathway in human melanoma cells.
    Raut PK, Lee HS, Joo SH, Chun KS.
    Food Chem Toxicol; 2021 Nov 28; 157():112604. PubMed ID: 34627931
    [Abstract] [Full Text] [Related]

  • 11. Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kappaB.
    Pozo-Guisado E, Merino JM, Mulero-Navarro S, Lorenzo-Benayas MJ, Centeno F, Alvarez-Barrientos A, Fernandez-Salguero PM.
    Int J Cancer; 2005 May 20; 115(1):74-84. PubMed ID: 15688415
    [Abstract] [Full Text] [Related]

  • 12. Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.
    Sethi G, Ahn KS, Aggarwal BB.
    Mol Cancer Res; 2008 Jun 20; 6(6):1059-70. PubMed ID: 18567808
    [Abstract] [Full Text] [Related]

  • 13. Hepatocyte growth factor enhances death receptor-induced apoptosis by up-regulating DR5.
    Li Y, Fan X, Goodwin CR, Laterra J, Xia S.
    BMC Cancer; 2008 Nov 07; 8():325. PubMed ID: 18992144
    [Abstract] [Full Text] [Related]

  • 14. Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3.
    Park JE, Kim DH, Ha E, Choi SM, Choi JS, Chun KS, Joo SH.
    Chem Biol Interact; 2019 Oct 01; 312():108799. PubMed ID: 31433961
    [Abstract] [Full Text] [Related]

  • 15. Thymoquinone upregulates TRAIL/TRAILR2 expression and attenuates hepatocellular carcinoma in vivo model.
    Helmy SA, El-Mesery M, El-Karef A, Eissa LA, El Gayar AM.
    Life Sci; 2019 Sep 15; 233():116673. PubMed ID: 31336121
    [Abstract] [Full Text] [Related]

  • 16. Thymoquinone, a bioactive component of black caraway seeds, causes G1 phase cell cycle arrest and apoptosis in triple-negative breast cancer cells with mutant p53.
    Sutton KM, Greenshields AL, Hoskin DW.
    Nutr Cancer; 2014 Sep 15; 66(3):408-18. PubMed ID: 24579801
    [Abstract] [Full Text] [Related]

  • 17. Thymoquinone attenuates monocrotaline-induced pulmonary artery hypertension via inhibiting pulmonary arterial remodeling in rats.
    Zhu N, Zhao X, Xiang Y, Ye S, Huang J, Hu W, Lv L, Zeng C.
    Int J Cardiol; 2016 Oct 15; 221():587-96. PubMed ID: 27420584
    [Abstract] [Full Text] [Related]

  • 18. Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells.
    Hastak K, Gupta S, Ahmad N, Agarwal MK, Agarwal ML, Mukhtar H.
    Oncogene; 2003 Jul 31; 22(31):4851-9. PubMed ID: 12894226
    [Abstract] [Full Text] [Related]

  • 19. All-trans-retinoic acid-induced apoptosis in human medulloblastoma: activation of caspase-3/poly(ADP-ribose) polymerase 1 pathway.
    Gumireddy K, Sutton LN, Phillips PC, Reddy CD.
    Clin Cancer Res; 2003 Sep 15; 9(11):4052-9. PubMed ID: 14519626
    [Abstract] [Full Text] [Related]

  • 20. Thymoquinone induces apoptosis of human renal carcinoma Caki-1 cells by inhibiting JAK2/STAT3 through pro-oxidant effect.
    Chae IG, Song NY, Kim DH, Lee MY, Park JM, Chun KS.
    Food Chem Toxicol; 2020 May 15; 139():111253. PubMed ID: 32165235
    [Abstract] [Full Text] [Related]

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