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351 related items for PubMed ID: 27091443

  • 1. Metal complexes of 3-(4-bromophenyl)-1-pyridin-2-ylprop-2-en-1-one thiosemicarbazone: cytotoxic activity and investigation on the mode of action of the gold(III) complex.
    Sâmia LB, Parrilha GL, Da Silva JG, Ramos JP, Souza-Fagundes EM, Castelli S, Vutey V, Desideri A, Beraldo H.
    Biometals; 2016 Jun; 29(3):515-26. PubMed ID: 27091443
    [Abstract] [Full Text] [Related]

  • 2. Gold(I) complexes with thiosemicarbazones: cytotoxicity against human tumor cell lines and inhibition of thioredoxin reductase activity.
    Lessa JA, Guerra JC, de Miranda LF, Romeiro CF, Da Silva JG, Mendes IC, Speziali NL, Souza-Fagundes EM, Beraldo H.
    J Inorg Biochem; 2011 Dec; 105(12):1729-39. PubMed ID: 22005449
    [Abstract] [Full Text] [Related]

  • 3. Cytotoxic activity, albumin and DNA binding of new copper(II) complexes with chalcone-derived thiosemicarbazones.
    Da Silva JG, Recio Despaigne AA, Louro SR, Bandeira CC, Souza-Fagundes EM, Beraldo H.
    Eur J Med Chem; 2013 Jul; 65():415-26. PubMed ID: 23747809
    [Abstract] [Full Text] [Related]

  • 4. Human topoisomerase IB is a target of a thiosemicarbazone copper(II) complex.
    Vutey V, Castelli S, D'Annessa I, Sâmia LB, Souza-Fagundes EM, Beraldo H, Desideri A.
    Arch Biochem Biophys; 2016 Sep 15; 606():34-40. PubMed ID: 27431056
    [Abstract] [Full Text] [Related]

  • 5. Metal complexes with 2-acetylpyridine-N(4)-orthochlorophenylthiosemicarbazone: cytotoxicity and effect on the enzymatic activity of thioredoxin reductase and glutathione reductase.
    Parrilha GL, Ferraz KS, Lessa JA, de Oliveira KN, Rodrigues BL, Ramos JP, Souza-Fagundes EM, Ott I, Beraldo H.
    Eur J Med Chem; 2014 Sep 12; 84():537-44. PubMed ID: 25058344
    [Abstract] [Full Text] [Related]

  • 6. Cobaltoceniumethynyl gold(I) as an unusual heterodinuclear bioorganometallic fragment to study the biological properties of alkynyl gold complexes.
    Vanicek S, Kopacka H, Wurst K, Vergeiner S, Kankowski S, Schur J, Bildstein B, Ott I.
    Dalton Trans; 2016 Jan 28; 45(4):1345-8. PubMed ID: 26732365
    [Abstract] [Full Text] [Related]

  • 7. Spectroscopic and electrochemical characterization of gold(I) and gold(III) complexes with glyoxaldehyde bis(thiosemicarbazones): cytotoxicity against human tumor cell lines and inhibition of thioredoxin reductase activity.
    Lessa JA, Ferraz KS, Guerra JC, de Miranda LF, Romeiro CF, Souza-Fagundes EM, Barbeira PJ, Beraldo H.
    Biometals; 2012 Jun 28; 25(3):587-98. PubMed ID: 22526562
    [Abstract] [Full Text] [Related]

  • 8. Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl2 Complexes.
    Truong D, Sullivan MP, Tong KKH, Steel TR, Prause A, Lovett JH, Andersen JW, Jamieson SMF, Harris HH, Ott I, Weekley CM, Hummitzsch K, Söhnel T, Hanif M, Metzler-Nolte N, Goldstone DC, Hartinger CG.
    Inorg Chem; 2020 Mar 02; 59(5):3281-3289. PubMed ID: 32073260
    [Abstract] [Full Text] [Related]

  • 9. Gold(I) thiotetrazolates as thioredoxin reductase inhibitors and antiproliferative agents.
    Serebryanskaya TV, Lyakhov AS, Ivashkevich LS, Schur J, Frias C, Prokop A, Ott I.
    Dalton Trans; 2015 Jan 21; 44(3):1161-9. PubMed ID: 25413270
    [Abstract] [Full Text] [Related]

  • 10. Novel thiosemicarbazones of the ApT and DpT series and their copper complexes: identification of pronounced redox activity and characterization of their antitumor activity.
    Jansson PJ, Sharpe PC, Bernhardt PV, Richardson DR.
    J Med Chem; 2010 Aug 12; 53(15):5759-69. PubMed ID: 20597487
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, crystal structure and antiproliferative mechanisms of 2-acetylpyridine-thiosemicarbazones Ga(III) with a greater selectivity against tumor cells.
    Qi J, Zheng Y, Qian K, Tian L, Zhang GX, Cheng Z, Wang Y.
    J Inorg Biochem; 2017 Dec 12; 177():110-117. PubMed ID: 28946027
    [Abstract] [Full Text] [Related]

  • 12. Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.
    Kowol CR, Trondl R, Heffeter P, Arion VB, Jakupec MA, Roller A, Galanski MS, Berger W, Keppler BK.
    J Med Chem; 2009 Aug 27; 52(16):5032-43. PubMed ID: 19637923
    [Abstract] [Full Text] [Related]

  • 13. N(4)-tolyl-2-acetylpyridine thiosemicarbazones and their platinum(II,IV) and gold(III) complexes: cytotoxicity against human glioma cells and studies on the mode of action.
    Ferraz KS, Da Silva JG, Costa FM, Mendes BM, Rodrigues BL, dos Santos RG, Beraldo H.
    Biometals; 2013 Oct 27; 26(5):677-91. PubMed ID: 23749148
    [Abstract] [Full Text] [Related]

  • 14. Cationic and Neutral N-Heterocyclic Carbene Gold(I) Complexes: Cytotoxicity, NCI-60 Screening, Cellular Uptake, Inhibition of Mammalian Thioredoxin Reductase, and Reactive Oxygen Species Formation.
    Zhang C, Hemmert C, Gornitzka H, Cuvillier O, Zhang M, Sun RW.
    ChemMedChem; 2018 Jun 20; 13(12):1218-1229. PubMed ID: 29603648
    [Abstract] [Full Text] [Related]

  • 15. 2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.
    Richardson DR, Kalinowski DS, Richardson V, Sharpe PC, Lovejoy DB, Islam M, Bernhardt PV.
    J Med Chem; 2009 Mar 12; 52(5):1459-70. PubMed ID: 19216562
    [Abstract] [Full Text] [Related]

  • 16. Comparative study of the antitumoral activity of phosphine-thiosemicarbazone gold(I) complexes obtained by different methodologies.
    González-Barcia LM, Fernández-Fariña S, Rodríguez-Silva L, Bermejo MR, González-Noya AM, Pedrido R.
    J Inorg Biochem; 2020 Feb 12; 203():110931. PubMed ID: 31786438
    [Abstract] [Full Text] [Related]

  • 17. Gold(I) and Gold(III) N-Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase.
    Büssing R, Karge B, Lippmann P, Jones PG, Brönstrup M, Ott I.
    ChemMedChem; 2021 Nov 19; 16(22):3402-3409. PubMed ID: 34268875
    [Abstract] [Full Text] [Related]

  • 18. Gold(I) NHC Complexes: Antiproliferative Activity, Cellular Uptake, Inhibition of Mammalian and Bacterial Thioredoxin Reductases, and Gram-Positive Directed Antibacterial Effects.
    Schmidt C, Karge B, Misgeld R, Prokop A, Franke R, Brönstrup M, Ott I.
    Chemistry; 2017 Feb 03; 23(8):1869-1880. PubMed ID: 27865002
    [Abstract] [Full Text] [Related]

  • 19. Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells.
    Ohui K, Stepanenko I, Besleaga I, Babak MV, Stafi R, Darvasiova D, Giester G, Pósa V, Enyedy EA, Vegh D, Rapta P, Ang WH, Popović-Bijelić A, Arion VB.
    Biomolecules; 2020 Sep 19; 10(9):. PubMed ID: 32961653
    [Abstract] [Full Text] [Related]

  • 20. Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity.
    Ng HL, Chen S, Chew EH, Chui WK.
    Eur J Med Chem; 2016 Jun 10; 115():63-74. PubMed ID: 26994844
    [Abstract] [Full Text] [Related]

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