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Journal Abstract Search

716 related items for PubMed ID: 27107592

  • 1. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
    Cai D, Qiu Z, Yao W, Liu Y, Huang H, Liao S, Luo Q, Xie L, Lin Z.
    Cancer Chemother Pharmacol; 2016 Jun; 77(6):1217-29. PubMed ID: 27107592
    [Abstract] [Full Text] [Related]

  • 2. DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.
    Qiao F, Zuo D, Shen X, Qi H, Wang H, Zhang W, Wu Y.
    Cancer Chemother Pharmacol; 2012 Aug; 70(2):259-70. PubMed ID: 22752214
    [Abstract] [Full Text] [Related]

  • 3. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 4. A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer.
    Ahn S, Hwang DJ, Barrett CM, Yang J, Duke CB, Miller DD, Dalton JT.
    Cancer Chemother Pharmacol; 2011 Feb 01; 67(2):293-304. PubMed ID: 20383708
    [Abstract] [Full Text] [Related]

  • 5. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G, Cecconet L, Leszl A, Basso G, Brun P, Salvador A, Dall'Acqua F, Diana P, Barraja P, Cirrincione G.
    Cancer Chemother Pharmacol; 2009 Nov 01; 64(6):1235-51. PubMed ID: 19363609
    [Abstract] [Full Text] [Related]

  • 6. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.
    Wu S, Guo Z, Hopkins CD, Wei N, Chu E, Wipf P, Schmitz JC.
    Oncotarget; 2015 Dec 01; 6(38):40866-79. PubMed ID: 26506423
    [Abstract] [Full Text] [Related]

  • 7. Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.
    Wong VK, Chiu P, Chung SS, Chow LM, Zhao YZ, Yang BB, Ko BC.
    Clin Cancer Res; 2005 Aug 15; 11(16):6002-11. PubMed ID: 16115945
    [Abstract] [Full Text] [Related]

  • 8. DAT-230, a Novel Microtubule Inhibitor, Induced Aberrant Mitosis and Apoptosis in SGC-7901 Cells.
    Qiao F, Zuo D, Wang H, Li Z, Qi H, Zhang W, Wu Y.
    Biol Pharm Bull; 2013 Aug 15; 36(2):193-201. PubMed ID: 23370351
    [Abstract] [Full Text] [Related]

  • 9. Pharmacokinetic profile of the microtubule stabilizer patupilone in tumor-bearing rodents and comparison of anti-cancer activity with other MTS in vitro and in vivo.
    O'Reilly T, Wartmann M, Brueggen J, Allegrini PR, Floersheimer A, Maira M, McSheehy PM.
    Cancer Chemother Pharmacol; 2008 Nov 15; 62(6):1045-54. PubMed ID: 18301895
    [Abstract] [Full Text] [Related]

  • 10. LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity.
    Qin M, Peng S, Liu N, Hu M, He Y, Li G, Chen H, He Y, Chen A, Wang X, Liu M, Chen Y, Yi Z.
    J Pharmacol Exp Ther; 2015 Dec 15; 355(3):473-83. PubMed ID: 26377911
    [Abstract] [Full Text] [Related]

  • 11. Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
    Guzmán EA, Xu Q, Pitts TP, Mitsuhashi KO, Baker C, Linley PA, Oestreicher J, Tendyke K, Winder PL, Suh EM, Wright AE.
    Int J Cancer; 2016 Nov 01; 139(9):2116-26. PubMed ID: 27376928
    [Abstract] [Full Text] [Related]

  • 12. Novel carbazole sulfonamide microtubule-destabilizing agents exert potent antitumor activity against esophageal squamous cell carcinoma.
    Niu F, Liu Y, Jing Z, Han G, Sun L, Yan L, Zhou L, Wu Y, Xu Y, Hu L, Zhao X.
    Cancer Lett; 2018 Apr 28; 420():60-71. PubMed ID: 29408653
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents.
    Cao D, Han X, Wang G, Yang Z, Peng F, Ma L, Zhang R, Ye H, Tang M, Wu W, Lei K, Wen J, Chen J, Qiu J, Liang X, Ran Y, Sang Y, Xiang M, Peng A, Chen L.
    Eur J Med Chem; 2013 Apr 28; 62():579-89. PubMed ID: 23425970
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q, Wang Y, Wang R, Lai W, Tang L, Tao Y, Liu Y, Zhang R, Huang L, Xiang H, Zeng S, Gou L, Chen H, Yao Y, Yang J.
    Eur J Med Chem; 2018 Aug 05; 156():162-179. PubMed ID: 30006162
    [Abstract] [Full Text] [Related]

  • 15. COH-203, a novel microtubule inhibitor, exhibits potent anti-tumor activity via p53-dependent senescence in hepatocellular carcinoma.
    Qi H, Zuo DY, Bai ZS, Xu JW, Li ZQ, Shen QR, Wang ZW, Zhang WG, Wu YL.
    Biochem Biophys Res Commun; 2014 Dec 12; 455(3-4):262-8. PubMed ID: 25449279
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y, Lin H, Ou C, Cao Y, An B, Yan J, Li X.
    Eur J Med Chem; 2019 Nov 15; 182():111670. PubMed ID: 31499359
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

  • 18. Pt(IV) prodrugs containing microtubule inhibitors displayed potent antitumor activity and ability to overcome cisplatin resistance.
    Li L, Huang X, Huang R, Gou S, Wang Z, Wang H.
    Eur J Med Chem; 2018 Aug 05; 156():666-679. PubMed ID: 30031977
    [Abstract] [Full Text] [Related]

  • 19. A novel microtubule depolymerizing colchicine analogue triggers apoptosis and autophagy in HCT-116 colon cancer cells.
    Kumar A, Singh B, Sharma PR, Bharate SB, Saxena AK, Mondhe DM.
    Cell Biochem Funct; 2016 Mar 05; 34(2):69-81. PubMed ID: 26919061
    [Abstract] [Full Text] [Related]

  • 20. C118P, a novel microtubule inhibitor with anti-angiogenic and vascular disrupting activities, exerts anti-tumor effects against hepatocellular carcinoma.
    Yang M, Su Y, Wang Z, Du D, Wei S, Liao Z, Zhang Q, Zhao L, Zhang X, Han L, Jiang J, Zhan M, Sun L, Yuan S, Zhou Z.
    Biochem Pharmacol; 2021 Aug 05; 190():114641. PubMed ID: 34077738
    [Abstract] [Full Text] [Related]

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