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Journal Abstract Search
716 related items for PubMed ID: 27107592
41. A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule. Liou JP, Hsu KS, Kuo CC, Chang CY, Chang JY. J Pharmacol Exp Ther; 2007 Oct; 323(1):398-405. PubMed ID: 17660383 [Abstract] [Full Text] [Related]
42. Development of Novel Bis(indolyl)-hydrazide-Hydrazone Derivatives as Potent Microtubule-Targeting Cytotoxic Agents against A549 Lung Cancer Cells. Das Mukherjee D, Kumar NM, Tantak MP, Das A, Ganguli A, Datta S, Kumar D, Chakrabarti G. Biochemistry; 2016 May 31; 55(21):3020-35. PubMed ID: 27110637 [Abstract] [Full Text] [Related]
43. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities. Liu Z, Zhou Z, Tian W, Fan X, Xue D, Yu L, Yu Q, Long YQ. ChemMedChem; 2012 Apr 31; 7(4):680-93. PubMed ID: 22311585 [Abstract] [Full Text] [Related]
44. SKLB-14b, a novel oral microtubule-destabilizing agent based on hydroxamic acid with potent anti-tumor and anti-multidrug resistance activities. Zhang W, Yang L, Si W, Tang M, Bai P, Zhu Z, Kuang S, Liu J, Shi M, Huang J, Chen X, Li D, Wen Y, Yang Z, Xiao K, Chen L. Bioorg Chem; 2022 Nov 31; 128():106053. PubMed ID: 35964504 [Abstract] [Full Text] [Related]
45. Design and synthesis of imidazo[2,1-b]thiazole linked triazole conjugates: Microtubule-destabilizing agents. Shaik SP, Nayak VL, Sultana F, Rao AVS, Shaik AB, Babu KS, Kamal A. Eur J Med Chem; 2017 Jan 27; 126():36-51. PubMed ID: 27744185 [Abstract] [Full Text] [Related]
46. Synthesis and biological evaluation of 1-benzylidene-3,4-dihydronaphthalen-2-one as a new class of microtubule-targeting agents. Liu J, Zheng CH, Ren XH, Zhou F, Li W, Zhu J, Lv JG, Zhou YJ. J Med Chem; 2012 Jun 28; 55(12):5720-33. PubMed ID: 22676247 [Abstract] [Full Text] [Related]
47. A novel colchicine-based microtubule inhibitor exhibits potent antitumor activity by inducing mitochondrial mediated apoptosis in MIA PaCa-2 pancreatic cancer cells. Kumar A, Singh B, Mahajan G, Sharma PR, Bharate SB, Mintoo MJ, Mondhe DM. Tumour Biol; 2016 Oct 28; 37(10):13121-13136. PubMed ID: 27449046 [Abstract] [Full Text] [Related]
48. Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models. Sampath D, Greenberger LM, Beyer C, Hari M, Liu H, Baxter M, Yang S, Rios C, Discafani C. Clin Cancer Res; 2006 Jun 01; 12(11 Pt 1):3459-69. PubMed ID: 16740771 [Abstract] [Full Text] [Related]
49. Ferulin C triggers potent PAK1 and p21-mediated anti-tumor effects in breast cancer by inhibiting Tubulin polymerization in vitro and in vivo. Yao D, Pan D, Zhen Y, Huang J, Wang J, Zhang J, He Z. Pharmacol Res; 2020 Feb 01; 152():104605. PubMed ID: 31863866 [Abstract] [Full Text] [Related]
50. Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway. Ho CH, Hsu JL, Liu SP, Hsu LC, Chang WL, Chao CC, Guh JH. Prostate; 2015 Sep 01; 75(13):1454-66. PubMed ID: 26180030 [Abstract] [Full Text] [Related]
51. Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities. Zhu H, Li W, Shuai W, Liu Y, Yang L, Tan Y, Zheng T, Yao H, Xu J, Zhu Z, Yang DH, Chen ZS, Xu S. Eur J Med Chem; 2021 Apr 15; 216():113316. PubMed ID: 33676300 [Abstract] [Full Text] [Related]
52. Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition. Yi JM, Zhang XF, Huan XJ, Song SS, Wang W, Tian QT, Sun YM, Chen Y, Ding J, Wang YQ, Yang CH, Miao ZH. Oncotarget; 2015 Apr 20; 6(11):8960-73. PubMed ID: 25840421 [Abstract] [Full Text] [Related]
53. The microtubule depolymerizing agent CYT997 causes extensive ablation of tumor vasculature in vivo. Burns CJ, Fantino E, Powell AK, Shnyder SD, Cooper PA, Nelson S, Christophi C, Malcontenti-Wilson C, Dubljevic V, Harte MF, Joffe M, Phillips ID, Segal D, Wilks AF, Smith GD. J Pharmacol Exp Ther; 2011 Dec 20; 339(3):799-806. PubMed ID: 21917561 [Abstract] [Full Text] [Related]
54. 6r, a novel oxadiazole analogue of ethacrynic acid, exhibits antitumor activity both in vitro and in vivo by induction of cell apoptosis and S-phase arrest. Zhang P, Chen JH, Dong X, Tang MT, Gao LY, Zhao GS, Yu LG, Guo XL. Biomed Pharmacother; 2013 Feb 20; 67(1):58-65. PubMed ID: 23201007 [Abstract] [Full Text] [Related]
55. Molecular mechanisms of the antitumor activity of SB225002: a novel microtubule inhibitor. Goda AE, Koyama M, Sowa Y, Elokely KM, Yoshida T, Kim BY, Sakai T. Biochem Pharmacol; 2013 Jun 15; 85(12):1741-52. PubMed ID: 23611835 [Abstract] [Full Text] [Related]
56. Apicularen A induces cell death through Fas ligand up-regulation and microtubule disruption by tubulin down-regulation in HM7 human colon cancer cells. Kim JS, Lee YC, Nam HT, Li G, Yun EJ, Song KS, Seo KS, Park JH, Ahn JW, Zee O, Park JI, Yoon WH, Lim K, Hwang BD. Clin Cancer Res; 2007 Nov 01; 13(21):6509-17. PubMed ID: 17975164 [Abstract] [Full Text] [Related]
57. Anticancer effects of KI-10F: a novel compound affecting apoptosis, angiogenesis and cell growth in colon cancer. Hong SW, Jung KH, Choi MJ, Kim DY, Lee HS, Zheng HM, Li GY, El-Deeb IM, Park BS, Lee SH, Hong SS. Int J Oncol; 2012 Nov 01; 41(5):1715-22. PubMed ID: 22941304 [Abstract] [Full Text] [Related]
58. Synthesis and biological evaluation of 1-phenyl-1,2,3,4-dihydroisoquinoline compounds as tubulin polymerization inhibitors. Zheng CH, Chen J, Liu J, Zhou XT, Liu N, Shi D, Huang JJ, Lv JG, Zhu J, Zhou YJ. Arch Pharm (Weinheim); 2012 Jun 01; 345(6):454-62. PubMed ID: 22415658 [Abstract] [Full Text] [Related]
59. Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase. Królewska-Golińska K, Cieślak MJ, Sobczak M, Dolot R, Radzikowska-Cieciura E, Napiórkowska M, Wybrańska I, Nawrot B. Anticancer Agents Med Chem; 2019 Jun 01; 19(3):375-388. PubMed ID: 30465514 [Abstract] [Full Text] [Related]
60. Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin. Gao F, Liang Y, Zhou P, Cheng J, Ding K, Wang Y. Eur J Med Chem; 2019 Sep 15; 178():177-194. PubMed ID: 31185410 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]