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Journal Abstract Search

349 related items for PubMed ID: 27110637

  • 1. Development of Novel Bis(indolyl)-hydrazide-Hydrazone Derivatives as Potent Microtubule-Targeting Cytotoxic Agents against A549 Lung Cancer Cells.
    Das Mukherjee D, Kumar NM, Tantak MP, Das A, Ganguli A, Datta S, Kumar D, Chakrabarti G.
    Biochemistry; 2016 May 31; 55(21):3020-35. PubMed ID: 27110637
    [Abstract] [Full Text] [Related]

  • 2. NMK-TD-100, a novel microtubule modulating agent, blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin.
    Bhattacharya S, Kumar NM, Ganguli A, Tantak MP, Kumar D, Chakrabarti G.
    PLoS One; 2013 May 31; 8(10):e76286. PubMed ID: 24116100
    [Abstract] [Full Text] [Related]

  • 3. NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
    Das Mukherjee D, Kumar NM, Tantak MP, Datta S, Ghosh Dastidar D, Kumar D, Chakrabarti G.
    Biochim Biophys Acta Mol Cell Res; 2020 Oct 31; 1867(10):118762. PubMed ID: 32502617
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of C5-tethered indolyl-3-glyoxylamide derivatives as tubulin polymerization inhibitors.
    Guggilapu SD, Lalita G, Reddy TS, Prajapti SK, Nagarsenkar A, Ramu S, Brahma UR, Lakshmi UJ, Vegi GMN, Bhargava SK, Babu BN.
    Eur J Med Chem; 2017 Mar 10; 128():1-12. PubMed ID: 28131777
    [Abstract] [Full Text] [Related]

  • 5. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 6. Colchicine induces autophagy and senescence in lung cancer cells at clinically admissible concentration: potential use of colchicine in combination with autophagy inhibitor in cancer therapy.
    Bhattacharya S, Das A, Datta S, Ganguli A, Chakrabarti G.
    Tumour Biol; 2016 Aug 01; 37(8):10653-64. PubMed ID: 26867767
    [Abstract] [Full Text] [Related]

  • 7. Design and synthesis of bis(indolyl)ketohydrazide-hydrazones: Identification of potent and selective novel tubulin inhibitors.
    Tantak MP, Klingler L, Arun V, Kumar A, Sadana R, Kumar D.
    Eur J Med Chem; 2017 Aug 18; 136():184-194. PubMed ID: 28494255
    [Abstract] [Full Text] [Related]

  • 8. Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells.
    Acharya BR, Chatterjee A, Ganguli A, Bhattacharya S, Chakrabarti G.
    Biochimie; 2014 Feb 18; 97():78-91. PubMed ID: 24113316
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of curcumin inspired indole analogues as tubulin polymerization inhibitors.
    Sri Ramya PV, Angapelly S, Guntuku L, Singh Digwal C, Nagendra Babu B, Naidu VGM, Kamal A.
    Eur J Med Chem; 2017 Feb 15; 127():100-114. PubMed ID: 28038323
    [Abstract] [Full Text] [Related]

  • 10. Design and synthesis of imidazo[2,1-b]thiazole linked triazole conjugates: Microtubule-destabilizing agents.
    Shaik SP, Nayak VL, Sultana F, Rao AVS, Shaik AB, Babu KS, Kamal A.
    Eur J Med Chem; 2017 Jan 27; 126():36-51. PubMed ID: 27744185
    [Abstract] [Full Text] [Related]

  • 11. New indole-based chalconoids as tubulin-targeting antiproliferative agents.
    Mirzaei H, Shokrzadeh M, Modanloo M, Ziar A, Riazi GH, Emami S.
    Bioorg Chem; 2017 Dec 27; 75():86-98. PubMed ID: 28922629
    [Abstract] [Full Text] [Related]

  • 12. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G, Cecconet L, Leszl A, Basso G, Brun P, Salvador A, Dall'Acqua F, Diana P, Barraja P, Cirrincione G.
    Cancer Chemother Pharmacol; 2009 Nov 27; 64(6):1235-51. PubMed ID: 19363609
    [Abstract] [Full Text] [Related]

  • 13. A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer.
    Ahn S, Hwang DJ, Barrett CM, Yang J, Duke CB, Miller DD, Dalton JT.
    Cancer Chemother Pharmacol; 2011 Feb 27; 67(2):293-304. PubMed ID: 20383708
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, antiproliferative and apoptosis induction potential activities of novel bis(indolyl)hydrazide-hydrazone derivatives.
    Sreenivasulu R, Reddy KT, Sujitha P, Kumar CG, Raju RR.
    Bioorg Med Chem; 2019 Mar 15; 27(6):1043-1055. PubMed ID: 30773423
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 16. N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia.
    Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira AB, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, de Souza Melo CP, Silveira AB, Leal PC, Frederico MJ, do Nascimento LF, Santos AR, Andricopulo AD, Day BW, Yunes RA, Vogt A, Yunes JA, Nunes RJ.
    Eur J Med Chem; 2015 Apr 01; 96():504-18. PubMed ID: 25951294
    [Abstract] [Full Text] [Related]

  • 17. Genistein arrests cell cycle progression of A549 cells at the G(2)/M phase and depolymerizes interphase microtubules through binding to a unique site of tubulin.
    Mukherjee S, Acharya BR, Bhattacharyya B, Chakrabarti G.
    Biochemistry; 2010 Mar 02; 49(8):1702-12. PubMed ID: 20085293
    [Abstract] [Full Text] [Related]

  • 18. Indicine N-oxide binds to tubulin at a distinct site and inhibits the assembly of microtubules: a mechanism for its cytotoxic activity.
    Appadurai P, Rathinasamy K.
    Toxicol Lett; 2014 Feb 10; 225(1):66-77. PubMed ID: 24300171
    [Abstract] [Full Text] [Related]

  • 19. Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase.
    Królewska-Golińska K, Cieślak MJ, Sobczak M, Dolot R, Radzikowska-Cieciura E, Napiórkowska M, Wybrańska I, Nawrot B.
    Anticancer Agents Med Chem; 2019 Feb 10; 19(3):375-388. PubMed ID: 30465514
    [Abstract] [Full Text] [Related]

  • 20. Cytotoxic activity and cytostatic mechanism of novel 2-arylbenzo[b]furans.
    Yang H, Pang JY, Cai YC, Xu ZL, Xian LJ.
    J Pharm Pharmacol; 2006 Sep 10; 58(9):1281-7. PubMed ID: 16945188
    [Abstract] [Full Text] [Related]

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