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Journal Abstract Search

619 related items for PubMed ID: 27138035

  • 1. Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents.
    Duan YT, Man RJ, Tang DJ, Yao YF, Tao XX, Yu C, Liang XY, Makawana JA, Zou MJ, Wang ZC, Zhu HL.
    Sci Rep; 2016 May 03; 6():25387. PubMed ID: 27138035
    [Abstract] [Full Text] [Related]

  • 2. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
    Sun J, Chen L, Liu C, Wang Z, Zuo D, Pan J, Qi H, Bao K, Wu Y, Zhang W.
    Chem Biol Drug Des; 2015 Dec 20; 86(6):1541-7. PubMed ID: 26202587
    [Abstract] [Full Text] [Related]

  • 6. Identification of novel 1-indolyl acetate-5-nitroimidazole derivatives of combretastatin A-4 as potential tubulin polymerization inhibitors.
    Yao YF, Wang ZC, Wu SY, Li QF, Yu C, Liang XY, Lv PC, Duan YT, Zhu HL.
    Biochem Pharmacol; 2017 Aug 01; 137():10-28. PubMed ID: 28456516
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR, Zong H, Ketkar A, Madadi NR, Janganati V, Eoff RL, Guzman ML, Crooks PA.
    Eur J Med Chem; 2015 Mar 06; 92():212-20. PubMed ID: 25557492
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
    Ruan BF, Lu X, Li TT, Tang JF, Wei Y, Wang XL, Zheng SL, Yao RS, Zhu HL.
    Bioorg Med Chem; 2012 Jan 15; 20(2):1113-21. PubMed ID: 22189271
    [Abstract] [Full Text] [Related]

  • 9. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
    [Abstract] [Full Text] [Related]

  • 10. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM.
    J Enzyme Inhib Med Chem; 2021 Dec 19; 36(1):802-818. PubMed ID: 33730937
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C, Sathish M, Anchi P, Tokala R, Lakshmi UJ, Reddy VG, Shankaraiah N, Godugu C, Kamal A.
    ChemMedChem; 2019 Dec 17; 14(24):2052-2060. PubMed ID: 31674147
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 13. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S, Mirzaei S, Reza Jafari-Nik M, Hadizadeh F, Eisvand F, Mosaffa F, Ghodsi R.
    Bioorg Chem; 2021 Jul 01; 112():104904. PubMed ID: 33933802
    [Abstract] [Full Text] [Related]

  • 15. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
    Nakamura M, Kajita D, Matsumoto Y, Hashimoto Y.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7381-91. PubMed ID: 24139940
    [Abstract] [Full Text] [Related]

  • 16. Design, concise synthesis and evaluation of novel amide-based combretastatin A-4 analogues as potent tubulin inhibitors.
    Ma Y, Wang T, Cheng L, Ma X, Li R, Zhang M, Chen J, Zhao P.
    Bioorg Med Chem Lett; 2024 Aug 01; 108():129816. PubMed ID: 38806101
    [Abstract] [Full Text] [Related]

  • 17. Novel Combretastatin A-4 Analogs-Design, Synthesis, and Antiproliferative and Anti-Tubulin Activity.
    Jędrzejczyk M, Morabito B, Żyżyńska-Granica B, Struga M, Janczak J, Aminpour M, Tuszynski JA, Huczyński A.
    Molecules; 2024 May 08; 29(10):. PubMed ID: 38792062
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, biological evaluation and molecular modeling of 1,3,4-oxadiazoline analogs of combretastatin-A4 as novel antitubulin agents.
    Hu Y, Lu X, Chen K, Yan R, Li QS, Zhu HL.
    Bioorg Med Chem; 2012 Jan 15; 20(2):903-9. PubMed ID: 22192936
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers.
    Kamal A, Shaik B, Nayak VL, Nagaraju B, Kapure JS, Shaheer Malik M, Shaik TB, Prasad B.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5155-67. PubMed ID: 25192811
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R.
    J Med Chem; 2006 Jun 29; 49(13):3906-15. PubMed ID: 16789746
    [Abstract] [Full Text] [Related]

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