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383 related items for PubMed ID: 27153754

  • 1. Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime+HI-6: Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics.
    Worek F, Koller M, Thiermann H, Wille T.
    Toxicology; 2016 Mar 28; 350-352():25-30. PubMed ID: 27153754
    [Abstract] [Full Text] [Related]

  • 2. Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro.
    Worek F, Aurbek N, Thiermann H.
    J Appl Toxicol; 2007 Mar 28; 27(6):582-8. PubMed ID: 17370251
    [Abstract] [Full Text] [Related]

  • 3. An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
    Kassa J, Karasova J, Musilek K, Kuca K.
    Toxicology; 2008 Jan 20; 243(3):311-6. PubMed ID: 18054821
    [Abstract] [Full Text] [Related]

  • 4. A comparison of the potency of the oxime HLö-7 and currently used oximes (HI-6, pralidoxime, obidoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J, Jun D, Hrabinová M.
    Acta Medica (Hradec Kralove); 2005 Jan 20; 48(2):81-6. PubMed ID: 16259317
    [Abstract] [Full Text] [Related]

  • 5. A comparison of the efficacy of a bispyridinium oxime--1,4-bis-(2-hydroxyiminomethylpyridinium) butane dibromide and currently used oximes to reactivate sarin, tabun or cyclosarin-inhibited acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J.
    Pharmazie; 2004 Oct 20; 59(10):795-8. PubMed ID: 15544060
    [Abstract] [Full Text] [Related]

  • 6. A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun-poisoned rats.
    Kassa J, Jun D, Kuca K.
    J Enzyme Inhib Med Chem; 2007 Jun 20; 22(3):297-300. PubMed ID: 17674811
    [Abstract] [Full Text] [Related]

  • 7. A structure-activity analysis of the variation in oxime efficacy against nerve agents.
    Maxwell DM, Koplovitz I, Worek F, Sweeney RE.
    Toxicol Appl Pharmacol; 2008 Sep 01; 231(2):157-64. PubMed ID: 18508103
    [Abstract] [Full Text] [Related]

  • 8. A comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques.
    Bajgar J, Hajek P, Zdarova JK, Kassa J, Paseka A, Slizova D, Krs O, Kuca K, Jun D, Fusek J, Capek L.
    J Enzyme Inhib Med Chem; 2010 Dec 01; 25(6):790-7. PubMed ID: 21054236
    [Abstract] [Full Text] [Related]

  • 9. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
    Maxwell DM, Brecht KM, Sweeney RE.
    Chem Biol Interact; 2013 Mar 25; 203(1):72-6. PubMed ID: 22982773
    [Abstract] [Full Text] [Related]

  • 10. Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes.
    Kuca K, Jun D.
    J Med Toxicol; 2006 Dec 25; 2(4):141-6. PubMed ID: 18072133
    [Abstract] [Full Text] [Related]

  • 11. In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase.
    Kuca K, Cabal J, Kassa J, Jun D, Hrabinova M.
    J Toxicol Environ Health A; 2006 Aug 25; 69(15):1431-40. PubMed ID: 16766478
    [Abstract] [Full Text] [Related]

  • 12. A comparison of the reactivating and therapeutic efficacy of newly developed oximes (K347, K628) with commonly used oximes (obidoxime, HI-6) against tabun in rats and mice.
    Kassa J, Karasova JZ, Kuca K, Musilek K.
    Drug Chem Toxicol; 2010 Jul 25; 33(3):227-32. PubMed ID: 20429807
    [Abstract] [Full Text] [Related]

  • 13. Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study.
    Worek F, Herkert NM, Koller M, Aurbek N, Thiermann H.
    Toxicol Lett; 2009 Jun 01; 187(2):119-23. PubMed ID: 19429253
    [Abstract] [Full Text] [Related]

  • 14. Reactivating potency of obidoxime, pralidoxime, HI 6 and HLö 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds.
    Worek F, Widmann R, Knopff O, Szinicz L.
    Arch Toxicol; 1998 Mar 01; 72(4):237-43. PubMed ID: 9587020
    [Abstract] [Full Text] [Related]

  • 15. An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice.
    Kassa J, Karasova J, Musilek K, Kuca K, Bajgar J.
    Clin Toxicol (Phila); 2009 Jan 01; 47(1):72-6. PubMed ID: 18686075
    [Abstract] [Full Text] [Related]

  • 16. Potency of novel oximes to reactivate sarin inhibited human cholinesterases.
    Jun D, Kuca K, Picha J, Koleckar V, Marek J.
    Drug Chem Toxicol; 2008 Jan 01; 31(1):1-9. PubMed ID: 18161504
    [Abstract] [Full Text] [Related]

  • 17. A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.
    Kassa J, Sepsova V, Matouskova L, Horova A, Musilek K.
    Toxicol Mech Methods; 2015 Mar 01; 25(3):229-33. PubMed ID: 25894563
    [Abstract] [Full Text] [Related]

  • 18. Reactivation of nerve agent inhibited human acetylcholinesterases by HI-6 and obidoxime.
    Puu G, Artursson E, Bucht G.
    Biochem Pharmacol; 1986 May 01; 35(9):1505-10. PubMed ID: 3518721
    [Abstract] [Full Text] [Related]

  • 19. Reactivation kinetics of a homologous series of bispyridinium bis-oximes with nerve agent-inhibited human acetylcholinesterase.
    Worek F, von der Wellen J, Musilek K, Kuca K, Thiermann H.
    Arch Toxicol; 2012 Sep 01; 86(9):1379-86. PubMed ID: 22437842
    [Abstract] [Full Text] [Related]

  • 20. Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?
    Aurbek N, Herkert NM, Koller M, Thiermann H, Worek F.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):215-9. PubMed ID: 20105433
    [Abstract] [Full Text] [Related]

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