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Journal Abstract Search

262 related items for PubMed ID: 27155899

  • 1. Design and synthesis of N-(4-aminopyridin-2-yl)amides as B-Raf(V600E) inhibitors.
    Li X, Shen J, Tan L, Zhang Z, Gao D, Luo J, Cheng H, Zhou X, Ma J, Ding K, Lu X.
    Bioorg Med Chem Lett; 2016 Jun 15; 26(12):2760-2763. PubMed ID: 27155899
    [Abstract] [Full Text] [Related]

  • 2. Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-Raf(V600E) and C-Raf kinase inhibitory activities.
    El-Damasy AK, Lee JH, Seo SH, Cho NC, Pae AN, Keum G.
    Eur J Med Chem; 2016 Jun 10; 115():201-16. PubMed ID: 27017549
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  • 3. Design, synthesis and biological evaluation of bis-aryl ureas and amides based on 2-amino-3-purinylpyridine scaffold as DFG-out B-Raf kinase inhibitors.
    Yang W, Chen Y, Zhou X, Gu Y, Qian W, Zhang F, Han W, Lu T, Tang W.
    Eur J Med Chem; 2015 Jan 07; 89():581-96. PubMed ID: 25462267
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  • 4. Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-RafV600E inhibitors.
    Wang GM, Wang X, Zhu JM, Guo BB, Yang Z, Xu ZJ, Li B, Wang HY, Meng LH, Zhu WL, Ding J.
    Acta Pharmacol Sin; 2017 Jul 07; 38(7):1059-1068. PubMed ID: 28414204
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of benzyl 2-(1H-imidazole-1-yl) pyrimidine analogues as selective and potent Raf inhibitors.
    Kim M, Lee J, Jung K, Kim H, Aman W, Ryu JS, Hah JM.
    Bioorg Med Chem Lett; 2014 Aug 01; 24(15):3600-4. PubMed ID: 24878193
    [Abstract] [Full Text] [Related]

  • 6. Design and synthesis of novel pyrrolo[2,3-b]pyridine derivatives targeting V600EBRAF.
    Abdel-Maksoud MS, Ali EMH, Ammar UM, Mersal KI, Yoo KH, Oh CH.
    Bioorg Med Chem; 2020 Jun 01; 28(11):115493. PubMed ID: 32340792
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  • 7. Design, synthesis, and biological evaluation of novel imidazole derivatives possessing terminal sulphonamides as potential BRAFV600Einhibitors.
    Ali EMH, Abdel-Maksoud MS, Ammar UM, Mersal KI, Ho Yoo K, Jooryeong P, Oh CH.
    Bioorg Chem; 2021 Jan 01; 106():104508. PubMed ID: 33280830
    [Abstract] [Full Text] [Related]

  • 8. Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular docking.
    Ammar UM, Abdel-Maksoud MS, Mersal KI, Ali EMH, Yoo KH, Choi HS, Lee JK, Cha SY, Oh CH.
    Bioorg Med Chem Lett; 2020 Oct 15; 30(20):127478. PubMed ID: 32781217
    [Abstract] [Full Text] [Related]

  • 9. Design and synthesis of a new series of highly potent RAF kinase-inhibiting triarylpyrazole derivatives possessing antiproliferative activity against melanoma cells.
    Khan MA, El-Gamal MI, Tarazi H, Choi HS, Oh CH.
    Future Med Chem; 2016 Dec 15; 8(18):2197-2211. PubMed ID: 27845592
    [Abstract] [Full Text] [Related]

  • 10. Design and discovery of thioether and nicotinamide containing sorafenib analogues as multikinase inhibitors targeting B-Raf, B-RafV600E and VEGFR-2.
    Sun S, He Z, Huang M, Wang N, He Z, Kong X, Yao J.
    Bioorg Med Chem; 2018 May 15; 26(9):2381-2391. PubMed ID: 29631788
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  • 19. Synthesis, in vitro antiproliferative activity, and kinase inhibitory effects of pyrazole-containing diarylureas and diarylamides.
    El-Gamal MI, Park BJ, Oh CH.
    Eur J Med Chem; 2018 Aug 05; 156():230-239. PubMed ID: 30006168
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  • 20. Design, synthesis, in-vitro antiproliferative activity and kinase profile of new picolinamide based 2-amido and ureido quinoline derivatives.
    El-Damasy AK, Seo SH, Cho NC, Kang SB, Pae AN, Kim KS, Keum G.
    Eur J Med Chem; 2015 Aug 28; 101():754-68. PubMed ID: 26218653
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