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Journal Abstract Search

174 related items for PubMed ID: 27162011

  • 1. 1-(5-Carboxyindazol-1-yl)propan-2-ones as dual inhibitors of cytosolic phospholipase A2α and fatty acid amide hydrolase: bioisosteric replacement of the carboxylic acid moiety.
    Althaus J, Hake T, Hanekamp W, Lehr M.
    J Enzyme Inhib Med Chem; 2016; 31(sup1):131-140. PubMed ID: 27162011
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  • 5. 1-Heteroaryl-3-phenoxypropan-2-ones as inhibitors of cytosolic phospholipase A₂α and fatty acid amide hydrolase: Effect of the replacement of the ether oxygen with sulfur and nitrogen moieties on enzyme inhibition and metabolic stability.
    Sundermann T, Fabian J, Hanekamp W, Lehr M.
    Bioorg Med Chem; 2015 May 15; 23(10):2579-92. PubMed ID: 25862211
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  • 10. Design and synthesis of 1-indol-1-yl-propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha.
    Ludwig J, Bovens S, Brauch C, Elfringhoff AS, Lehr M.
    J Med Chem; 2006 Apr 20; 49(8):2611-20. PubMed ID: 16610804
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  • 12. Structure-activity relationship studies on 1-(2-oxopropyl)indole-5-carboxylic acids acting as inhibitors of cytosolic phospholipase A2α: Effect of substituents at the indole 3-position on activity, solubility, and metabolic stability.
    Arnsmann M, Hanekamp W, Elfringhoff AS, Lehr M.
    Eur J Med Chem; 2017 Jan 05; 125():1107-1114. PubMed ID: 27810597
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  • 13. 1-(5-Carboxyindol-1-yl)propan-2-one inhibitors of human cytosolic phospholipase A2α: effect of substituents in position 3 of the indole scaffold on inhibitory potency, metabolic stability, solubility, and bioavailability.
    Bovens S, Schulze Elfringhoff A, Kaptur M, Reinhardt D, Schäfers M, Lehr M.
    J Med Chem; 2010 Dec 09; 53(23):8298-308. PubMed ID: 21067218
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  • 14. Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors.
    Deplano A, Cipriano M, Moraca F, Novellino E, Catalanotti B, Fowler CJ, Onnis V.
    J Enzyme Inhib Med Chem; 2019 Dec 09; 34(1):562-576. PubMed ID: 30688118
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  • 16. Design, synthesis, and biological evaluation of 3-(1-Aryl-1H-indol-5-yl)propanoic acids as new indole-based cytosolic phospholipase A2α inhibitors.
    Tomoo T, Nakatsuka T, Katayama T, Hayashi Y, Fujieda Y, Terakawa M, Nagahira K.
    J Med Chem; 2014 Sep 11; 57(17):7244-62. PubMed ID: 25102418
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  • 17. Investigations on the metabolic stability of cytosolic phospholipase A2α inhibitors with 1-indolylpropan-2-one structure.
    Fabian J, Hanekamp W, Thomas MH, Olivier JL, Lehr M.
    Chem Biol Interact; 2013 Nov 25; 206(2):356-63. PubMed ID: 24120545
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  • 18. Design and synthesis of 3-pyrrol-3-yl-3H-isobenzofuran-1-ones as inhibitors of human cytosolic phospholipase A2alpha.
    Hess M, Schulze Elfringhoff A, Lehr M.
    J Enzyme Inhib Med Chem; 2008 Dec 25; 23(6):946-57. PubMed ID: 18608744
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  • 19. Targeting Cytosolic Phospholipase A2α for Novel Anti-Inflammatory Agents.
    Soubhye J, van Antwerpen P, Dufrasne F.
    Curr Med Chem; 2018 Dec 25; 25(21):2418-2447. PubMed ID: 29345571
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