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216 related items for PubMed ID: 27172609

  • 1. MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans.
    Chen Y, Bharill S, O'Hagan R, Isacoff EY, Chalfie M.
    G3 (Bethesda); 2016 Apr 07; 6(4):1121-30. PubMed ID: 27172609
    [Abstract] [Full Text] [Related]

  • 2. Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins.
    Chen Y, Bharill S, Altun Z, O'Hagan R, Coblitz B, Isacoff EY, Chalfie M.
    Mol Biol Cell; 2016 Apr 15; 27(8):1272-85. PubMed ID: 26941331
    [Abstract] [Full Text] [Related]

  • 3. Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans.
    Chen Y, Bharill S, Isacoff EY, Chalfie M.
    Proc Natl Acad Sci U S A; 2015 Sep 15; 112(37):11690-5. PubMed ID: 26324944
    [Abstract] [Full Text] [Related]

  • 4. The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel.
    Chelur DS, Ernstrom GG, Goodman MB, Yao CA, Chen L, O' Hagan R, Chalfie M.
    Nature; 2002 Dec 12; 420(6916):669-73. PubMed ID: 12478294
    [Abstract] [Full Text] [Related]

  • 5. The DEG/ENaC protein MEC-10 regulates the transduction channel complex in Caenorhabditis elegans touch receptor neurons.
    Arnadóttir J, O'Hagan R, Chen Y, Goodman MB, Chalfie M.
    J Neurosci; 2011 Aug 31; 31(35):12695-704. PubMed ID: 21880930
    [Abstract] [Full Text] [Related]

  • 6. Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade.
    Brown AL, Fernandez-Illescas SM, Liao Z, Goodman MB.
    J Gen Physiol; 2007 Feb 31; 129(2):161-73. PubMed ID: 17261841
    [Abstract] [Full Text] [Related]

  • 7. Intersubunit interactions between mutant DEG/ENaCs induce synthetic neurotoxicity.
    Zhang W, Bianchi L, Lee WH, Wang Y, Israel S, Driscoll M.
    Cell Death Differ; 2008 Nov 31; 15(11):1794-803. PubMed ID: 18670436
    [Abstract] [Full Text] [Related]

  • 8. Temperature-sensitive mutant of the Caenorhabditis elegans neurotoxic MEC-4(d) DEG/ENaC channel identifies a site required for trafficking or surface maintenance.
    Royal DC, Bianchi L, Royal MA, Lizzio M, Mukherjee G, Nunez YO, Driscoll M.
    J Biol Chem; 2005 Dec 23; 280(51):41976-86. PubMed ID: 16239217
    [Abstract] [Full Text] [Related]

  • 9. MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation.
    Goodman MB, Ernstrom GG, Chelur DS, O'Hagan R, Yao CA, Chalfie M.
    Nature; 2002 Feb 28; 415(6875):1039-42. PubMed ID: 11875573
    [Abstract] [Full Text] [Related]

  • 10. Ca2+ permeability and Na+ conductance in cellular toxicity caused by hyperactive DEG/ENaC channels.
    Matthewman C, Miller-Fleming TW, Miller DM, Bianchi L.
    Am J Physiol Cell Physiol; 2016 Dec 01; 311(6):C920-C930. PubMed ID: 27760755
    [Abstract] [Full Text] [Related]

  • 11. The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals.
    O'Hagan R, Chalfie M, Goodman MB.
    Nat Neurosci; 2005 Jan 01; 8(1):43-50. PubMed ID: 15580270
    [Abstract] [Full Text] [Related]

  • 12. NRA-2, a nicalin homolog, regulates neuronal death by controlling surface localization of toxic Caenorhabditis elegans DEG/ENaC channels.
    Kamat S, Yeola S, Zhang W, Bianchi L, Driscoll M.
    J Biol Chem; 2014 Apr 25; 289(17):11916-11926. PubMed ID: 24567339
    [Abstract] [Full Text] [Related]

  • 13. A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans.
    Hong K, Driscoll M.
    Nature; 1994 Feb 03; 367(6462):470-3. PubMed ID: 8107806
    [Abstract] [Full Text] [Related]

  • 14. Spatial asymmetry in the mechanosensory phenotypes of the C. elegans DEG/ENaC gene mec-10.
    Chatzigeorgiou M, Grundy L, Kindt KS, Lee WH, Driscoll M, Schafer WR.
    J Neurophysiol; 2010 Dec 03; 104(6):3334-44. PubMed ID: 20881202
    [Abstract] [Full Text] [Related]

  • 15. Nanoscale organization of the MEC-4 DEG/ENaC sensory mechanotransduction channel in Caenorhabditis elegans touch receptor neurons.
    Cueva JG, Mulholland A, Goodman MB.
    J Neurosci; 2007 Dec 19; 27(51):14089-98. PubMed ID: 18094248
    [Abstract] [Full Text] [Related]

  • 16. Two novel DEG/ENaC channel subunits expressed in glia are needed for nose-touch sensitivity in Caenorhabditis elegans.
    Han L, Wang Y, Sangaletti R, D'Urso G, Lu Y, Shaham S, Bianchi L.
    J Neurosci; 2013 Jan 16; 33(3):936-49. PubMed ID: 23325233
    [Abstract] [Full Text] [Related]

  • 17. In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensation.
    Suzuki H, Kerr R, Bianchi L, Frøkjaer-Jensen C, Slone D, Xue J, Gerstbrein B, Driscoll M, Schafer WR.
    Neuron; 2003 Sep 11; 39(6):1005-17. PubMed ID: 12971899
    [Abstract] [Full Text] [Related]

  • 18. Pore-lining residues of MEC-4 and MEC-10 channel subunits tune the Caenorhabditis elegans degenerin channel's response to shear stress.
    Shi S, Mutchler SM, Blobner BM, Kashlan OB, Kleyman TR.
    J Biol Chem; 2018 Jul 06; 293(27):10757-10766. PubMed ID: 29743244
    [Abstract] [Full Text] [Related]

  • 19. Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors.
    Chatzigeorgiou M, Yoo S, Watson JD, Lee WH, Spencer WC, Kindt KS, Hwang SW, Miller DM, Treinin M, Driscoll M, Schafer WR.
    Nat Neurosci; 2010 Jul 06; 13(7):861-8. PubMed ID: 20512132
    [Abstract] [Full Text] [Related]

  • 20. Gravity force transduced by the MEC-4/MEC-10 DEG/ENaC channel modulates DAF-16/FoxO activity in Caenorhabditis elegans.
    Kim N, Dempsey CM, Kuan CJ, Zoval JV, O'Rourke E, Ruvkun G, Madou MJ, Sze JY.
    Genetics; 2007 Oct 06; 177(2):835-45. PubMed ID: 17720915
    [Abstract] [Full Text] [Related]

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