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383 related items for PubMed ID: 27174644

  • 1. CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves.
    Martínez-Muriana A, Mancuso R, Francos-Quijorna I, Olmos-Alonso A, Osta R, Perry VH, Navarro X, Gomez-Nicola D, López-Vales R.
    Sci Rep; 2016 May 13; 6():25663. PubMed ID: 27174644
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  • 3. Ablation of P2X7 receptor exacerbates gliosis and motoneuron death in the SOD1-G93A mouse model of amyotrophic lateral sclerosis.
    Apolloni S, Amadio S, Montilli C, Volonté C, D'Ambrosi N.
    Hum Mol Genet; 2013 Oct 15; 22(20):4102-16. PubMed ID: 23736299
    [Abstract] [Full Text] [Related]

  • 4. Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis.
    Bowerman M, Salsac C, Coque E, Eiselt É, Deschaumes RG, Brodovitch A, Burkly LC, Scamps F, Raoul C.
    Hum Mol Genet; 2015 Jun 15; 24(12):3440-56. PubMed ID: 25765661
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  • 5. Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology.
    Olmos-Alonso A, Schetters ST, Sri S, Askew K, Mancuso R, Vargas-Caballero M, Holscher C, Perry VH, Gomez-Nicola D.
    Brain; 2016 Mar 15; 139(Pt 3):891-907. PubMed ID: 26747862
    [Abstract] [Full Text] [Related]

  • 6. Inhibiting microglia proliferation after spinal cord injury improves recovery in mice and nonhuman primates.
    Poulen G, Aloy E, Bringuier CM, Mestre-Francés N, Artus EVF, Cardoso M, Perez JC, Goze-Bac C, Boukhaddaoui H, Lonjon N, Gerber YN, Perrin FE.
    Theranostics; 2021 Mar 15; 11(18):8640-8659. PubMed ID: 34522204
    [Abstract] [Full Text] [Related]

  • 7. Influence of methylene blue on microglia-induced inflammation and motor neuron degeneration in the SOD1(G93A) model for ALS.
    Dibaj P, Zschüntzsch J, Steffens H, Scheffel J, Göricke B, Weishaupt JH, Le Meur K, Kirchhoff F, Hanisch UK, Schomburg ED, Neusch C.
    PLoS One; 2012 Mar 15; 7(8):e43963. PubMed ID: 22952827
    [Abstract] [Full Text] [Related]

  • 8. System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.
    Mesci P, Zaïdi S, Lobsiger CS, Millecamps S, Escartin C, Seilhean D, Sato H, Mallat M, Boillée S.
    Brain; 2015 Jan 15; 138(Pt 1):53-68. PubMed ID: 25384799
    [Abstract] [Full Text] [Related]

  • 9. Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model.
    Fellner A, Barhum Y, Angel A, Perets N, Steiner I, Offen D, Lev N.
    Int J Mol Sci; 2017 Aug 01; 18(8):. PubMed ID: 28763002
    [Abstract] [Full Text] [Related]

  • 10. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Milanese M, Giribaldi F, Melone M, Bonifacino T, Musante I, Carminati E, Rossi PI, Vergani L, Voci A, Conti F, Puliti A, Bonanno G.
    Neurobiol Dis; 2014 Apr 01; 64():48-59. PubMed ID: 24361555
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  • 11. Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.
    Gowing G, Philips T, Van Wijmeersch B, Audet JN, Dewil M, Van Den Bosch L, Billiau AD, Robberecht W, Julien JP.
    J Neurosci; 2008 Oct 08; 28(41):10234-44. PubMed ID: 18842883
    [Abstract] [Full Text] [Related]

  • 12. Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression.
    Apolloni S, Fabbrizio P, Amadio S, Volonté C.
    J Neuroinflammation; 2016 Aug 22; 13(1):191. PubMed ID: 27549088
    [Abstract] [Full Text] [Related]

  • 13. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
    Beers DR, Henkel JS, Xiao Q, Zhao W, Wang J, Yen AA, Siklos L, McKercher SR, Appel SH.
    Proc Natl Acad Sci U S A; 2006 Oct 24; 103(43):16021-6. PubMed ID: 17043238
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  • 14. Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner.
    MacLean M, Juranek J, Cuddapah S, López-Díez R, Ruiz HH, Hu J, Frye L, Li H, Gugger PF, Schmidt AM.
    J Neuroinflammation; 2021 Jun 15; 18(1):139. PubMed ID: 34130712
    [Abstract] [Full Text] [Related]

  • 15. Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS).
    Van Dyke JM, Smit-Oistad IM, Macrander C, Krakora D, Meyer MG, Suzuki M.
    Exp Neurol; 2016 Mar 15; 277():275-282. PubMed ID: 26775178
    [Abstract] [Full Text] [Related]

  • 16. Treatment With the CSF1R Antagonist GW2580, Sensitizes Microglia to Reactive Oxygen Species.
    Soto-Diaz K, Vailati-Riboni M, Louie AY, McKim DB, Gaskins HR, Johnson RW, Steelman AJ.
    Front Immunol; 2021 Mar 15; 12():734349. PubMed ID: 34899694
    [Abstract] [Full Text] [Related]

  • 17. RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.
    Vallarola A, Sironi F, Tortarolo M, Gatto N, De Gioia R, Pasetto L, De Paola M, Mariani A, Ghosh S, Watson R, Kalmes A, Bonetto V, Bendotti C.
    J Neuroinflammation; 2018 Mar 01; 15(1):65. PubMed ID: 29495962
    [Abstract] [Full Text] [Related]

  • 18. Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis.
    Lee JD, McDonald TS, Fung JNT, Woodruff TM.
    Mol Neurobiol; 2020 Oct 01; 57(10):4143-4155. PubMed ID: 32676989
    [Abstract] [Full Text] [Related]

  • 19. H63D HFE genotype accelerates disease progression in animal models of amyotrophic lateral sclerosis.
    Nandar W, Neely EB, Simmons Z, Connor JR.
    Biochim Biophys Acta; 2014 Dec 01; 1842(12 Pt A):2413-26. PubMed ID: 25283820
    [Abstract] [Full Text] [Related]

  • 20. PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Ringer C, Büning LS, Schäfer MK, Eiden LE, Weihe E, Schütz B.
    Neurobiol Dis; 2013 Jun 01; 54():32-42. PubMed ID: 23466699
    [Abstract] [Full Text] [Related]

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