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198 related items for PubMed ID: 27185624
1. The E119D neuraminidase mutation identified in a multidrug-resistant influenza A(H1N1)pdm09 isolate severely alters viral fitness in vitro and in animal models. Abed Y, Bouhy X, L'Huillier AG, Rhéaume C, Pizzorno A, Retamal M, Fage C, Dubé K, Joly MH, Beaulieu E, Mallett C, Kaiser L, Boivin G. Antiviral Res; 2016 Aug; 132():6-12. PubMed ID: 27185624 [Abstract] [Full Text] [Related]
2. E119D Neuraminidase Mutation Conferring Pan-Resistance to Neuraminidase Inhibitors in an A(H1N1)pdm09 Isolate From a Stem-Cell Transplant Recipient. L'Huillier AG, Abed Y, Petty TJ, Cordey S, Thomas Y, Bouhy X, Schibler M, Simon A, Chalandon Y, van Delden C, Zdobnov E, Boquete-Suter P, Boivin G, Kaiser L. J Infect Dis; 2015 Dec 01; 212(11):1726-34. PubMed ID: 25985905 [Abstract] [Full Text] [Related]
3. In Vitro and In Vivo Characterization of Novel Neuraminidase Substitutions in Influenza A(H1N1)pdm09 Virus Identified Using Laninamivir-Mediated In Vitro Selection. Lloren KKS, Kwon JJ, Choi WS, Jeong JH, Ahn SJ, Choi YK, Baek YH, Song MS. J Virol; 2019 Mar 15; 93(6):. PubMed ID: 30602610 [Abstract] [Full Text] [Related]
4. Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets. Abed Y, Pizzorno A, Bouhy X, Rhéaume C, Boivin G. J Virol; 2014 Feb 15; 88(3):1652-8. PubMed ID: 24257597 [Abstract] [Full Text] [Related]
5. Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models. Abed Y, Tu V, Carbonneau J, Checkmahomed L, Venable MC, Fage C, Marie-Ève-Hamelin, Dufresne SF, Kobinger G, Boivin G. Antiviral Res; 2018 Nov 15; 159():26-34. PubMed ID: 30219318 [Abstract] [Full Text] [Related]
6. The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness. Tu V, Abed Y, Barbeau X, Carbonneau J, Fage C, Lagüe P, Boivin G. Antiviral Res; 2017 Jan 15; 137():6-13. PubMed ID: 27838351 [Abstract] [Full Text] [Related]
7. An I436N substitution confers resistance of influenza A(H1N1)pdm09 viruses to multiple neuraminidase inhibitors without affecting viral fitness. Kwon JJ, Choi WS, Jeong JH, Kim EH, Lee OJ, Yoon SW, Hwang J, Webby RJ, Govorkova EA, Choi YK, Baek YH, Song MS. J Gen Virol; 2018 Mar 15; 99(3):292-302. PubMed ID: 29493493 [Abstract] [Full Text] [Related]
8. Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus. Pizzorno A, Abed Y, Bouhy X, Beaulieu E, Mallett C, Russell R, Boivin G. Antimicrob Agents Chemother; 2012 Mar 15; 56(3):1208-14. PubMed ID: 22203589 [Abstract] [Full Text] [Related]
9. Permissive changes in the neuraminidase play a dominant role in improving the viral fitness of oseltamivir-resistant seasonal influenza A(H1N1) strains. Abed Y, Pizzorno A, Bouhy X, Boivin G. Antiviral Res; 2015 Feb 15; 114():57-61. PubMed ID: 25512229 [Abstract] [Full Text] [Related]
10. Selection of multi-drug resistant influenza A and B viruses under zanamivir pressure and their replication fitness in ferrets. Oh DY, Panozzo J, Vitesnik S, Farrukee R, Piedrafita D, Mosse J, Hurt AC. Antivir Ther; 2018 Feb 15; 23(4):295-306. PubMed ID: 28195559 [Abstract] [Full Text] [Related]
11. Impact of R152K and R368K neuraminidase catalytic substitutions on in vitro properties and virulence of recombinant A(H1N1)pdm09 viruses. Tu V, Abed Y, Fage C, Baz M, Boivin G. Antiviral Res; 2018 Jun 15; 154():110-115. PubMed ID: 29674164 [Abstract] [Full Text] [Related]
12. Predicting Permissive Mutations That Improve the Fitness of A(H1N1)pdm09 Viruses Bearing the H275Y Neuraminidase Substitution. Farrukee R, Gunalan V, Maurer-Stroh S, Reading PC, Hurt AC. J Virol; 2022 Aug 10; 96(15):e0091822. PubMed ID: 35867563 [Abstract] [Full Text] [Related]
13. Profiling and characterization of influenza virus N1 strains potentially resistant to multiple neuraminidase inhibitors. Baek YH, Song MS, Lee EY, Kim YI, Kim EH, Park SJ, Park KJ, Kwon HI, Pascua PN, Lim GJ, Kim S, Yoon SW, Kim MH, Webby RJ, Choi YK. J Virol; 2015 Jan 10; 89(1):287-99. PubMed ID: 25320319 [Abstract] [Full Text] [Related]
14. Emergence of Multidrug-Resistant Influenza A(H1N1)pdm09 Virus Variants in an Immunocompromised Child Treated With Oseltamivir and Zanamivir. Tamura D, DeBiasi RL, Okomo-Adhiambo M, Mishin VP, Campbell AP, Loechelt B, Wiedermann BL, Fry AM, Gubareva LV. J Infect Dis; 2015 Oct 15; 212(8):1209-13. PubMed ID: 25943200 [Abstract] [Full Text] [Related]
15. Characterization of oseltamivir-resistant influenza A(H1N1)pdm09 viruses in Taiwan in 2009-2011. Yang JR, Huang YP, Chang FY, Hsu LC, Huang HY, Pan YT, Lin YC, Wu HS, Liu MT. J Med Virol; 2013 Mar 15; 85(3):379-87. PubMed ID: 23280715 [Abstract] [Full Text] [Related]
17. Influenza A(H1N1)pdm09 resistance and cross-decreased susceptibility to oseltamivir and zanamivir antiviral drugs. Correia V, Santos LA, Gíria M, Almeida-Santos MM, Rebelo-de-Andrade H. J Med Virol; 2015 Jan 15; 87(1):45-56. PubMed ID: 25042157 [Abstract] [Full Text] [Related]
18. Comparable fitness and transmissibility between oseltamivir-resistant pandemic 2009 and seasonal H1N1 influenza viruses with the H275Y neuraminidase mutation. Wong DD, Choy KT, Chan RW, Sia SF, Chiu HP, Cheung PP, Chan MC, Peiris JS, Yen HL. J Virol; 2012 Oct 15; 86(19):10558-70. PubMed ID: 22811535 [Abstract] [Full Text] [Related]
19. Pandemic H1N1 2009 influenza virus with the H275Y oseltamivir resistance neuraminidase mutation shows a small compromise in enzyme activity and viral fitness. Brookes DW, Miah S, Lackenby A, Hartgroves L, Barclay WS. J Antimicrob Chemother; 2011 Mar 15; 66(3):466-70. PubMed ID: 21172786 [Abstract] [Full Text] [Related]
20. Droplet digital PCR to investigate quasi-species at codons 119 and 275 of the A(H1N1)pdm09 neuraminidase during zanamivir and oseltamivir therapies. Abed Y, Carbonneau J, L'Huillier AG, Kaiser L, Boivin G. J Med Virol; 2017 Apr 15; 89(4):737-741. PubMed ID: 27602879 [Abstract] [Full Text] [Related] Page: [Next] [New Search]