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Journal Abstract Search


263 related items for PubMed ID: 27196927

  • 1. Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin.
    Weisemann J, Stern D, Mahrhold S, Dorner BG, Rummel A.
    Toxins (Basel); 2016 May 17; 8(5):. PubMed ID: 27196927
    [Abstract] [Full Text] [Related]

  • 2. Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1.
    Mahrhold S, Bergström T, Stern D, Dorner BG, Åstot C, Rummel A.
    Biochem J; 2016 Sep 01; 473(17):2645-54. PubMed ID: 27313224
    [Abstract] [Full Text] [Related]

  • 3. Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.
    Rummel A.
    Curr Top Microbiol Immunol; 2017 Sep 01; 406():1-37. PubMed ID: 27921176
    [Abstract] [Full Text] [Related]

  • 4. SV2 is the protein receptor for botulinum neurotoxin A.
    Dong M, Yeh F, Tepp WH, Dean C, Johnson EA, Janz R, Chapman ER.
    Science; 2006 Apr 28; 312(5773):592-6. PubMed ID: 16543415
    [Abstract] [Full Text] [Related]

  • 5. Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
    Rummel A.
    Curr Top Microbiol Immunol; 2013 Apr 28; 364():61-90. PubMed ID: 23239349
    [Abstract] [Full Text] [Related]

  • 6. Structural basis of botulinum neurotoxin serotype A1 binding to human SV2A or SV2C receptors.
    Azzaz F, Hilaire D, Fantini J.
    Chem Biol Interact; 2023 Mar 01; 373():110384. PubMed ID: 36754227
    [Abstract] [Full Text] [Related]

  • 7. Understanding peptide competitive inhibition of botulinum neurotoxin A binding to SV2 protein via molecular dynamics simulations.
    Chang S, He HQ, Shen L, Wan H.
    Biopolymers; 2015 Oct 01; 103(10):597-608. PubMed ID: 26178648
    [Abstract] [Full Text] [Related]

  • 8. Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding.
    Gustafsson R, Zhang S, Masuyer G, Dong M, Stenmark P.
    Toxins (Basel); 2018 Apr 12; 10(4):. PubMed ID: 29649119
    [Abstract] [Full Text] [Related]

  • 9. Structural insights into the interaction of botulinum neurotoxin a with its neuronal receptor SV2C.
    Li X, Brunner C, Wu Y, Leka O, Schneider G, Kammerer RA.
    Toxicon; 2020 Feb 12; 175():36-43. PubMed ID: 31783045
    [Abstract] [Full Text] [Related]

  • 10. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
    Peng L, Tepp WH, Johnson EA, Dong M.
    PLoS Pathog; 2011 Mar 12; 7(3):e1002008. PubMed ID: 21483489
    [Abstract] [Full Text] [Related]

  • 11. Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A.
    Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, McMillan D, Ceska T, Lebon F, Jaussi R, Steinmetz MO, Schertler GF, Hoogenraad CC, Capitani G, Kammerer RA.
    Nature; 2014 Jan 02; 505(7481):108-11. PubMed ID: 24240280
    [Abstract] [Full Text] [Related]

  • 12. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F.
    Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR.
    Biochemistry; 2009 Jun 23; 48(24):5631-41. PubMed ID: 19476346
    [Abstract] [Full Text] [Related]

  • 13. Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
    Rummel A, Häfner K, Mahrhold S, Darashchonak N, Holt M, Jahn R, Beermann S, Karnath T, Bigalke H, Binz T.
    J Neurochem; 2009 Sep 23; 110(6):1942-54. PubMed ID: 19650874
    [Abstract] [Full Text] [Related]

  • 14. Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.
    Dong M, Liu H, Tepp WH, Johnson EA, Janz R, Chapman ER.
    Mol Biol Cell; 2008 Dec 23; 19(12):5226-37. PubMed ID: 18815274
    [Abstract] [Full Text] [Related]

  • 15. Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.
    Rummel A, Karnath T, Henke T, Bigalke H, Binz T.
    J Biol Chem; 2004 Jul 16; 279(29):30865-70. PubMed ID: 15123599
    [Abstract] [Full Text] [Related]

  • 16. Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
    Liu Z, Lee PG, Krez N, Lam KH, Liu H, Przykopanski A, Chen P, Yao G, Zhang S, Tremblay JM, Perry K, Shoemaker CB, Rummel A, Dong M, Jin R.
    Nat Commun; 2023 Apr 24; 14(1):2338. PubMed ID: 37095076
    [Abstract] [Full Text] [Related]

  • 17. Association of botulinum neurotoxin serotypes a and B with synaptic vesicle protein complexes.
    Baldwin MR, Barbieri JT.
    Biochemistry; 2007 Mar 20; 46(11):3200-10. PubMed ID: 17311420
    [Abstract] [Full Text] [Related]

  • 18. The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves.
    Mahrhold S, Rummel A, Bigalke H, Davletov B, Binz T.
    FEBS Lett; 2006 Apr 03; 580(8):2011-4. PubMed ID: 16545378
    [Abstract] [Full Text] [Related]

  • 19. Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C.
    Benoit RM, Schärer MA, Wieser MM, Li X, Frey D, Kammerer RA.
    Sci Rep; 2017 Mar 02; 7():43588. PubMed ID: 28252640
    [Abstract] [Full Text] [Related]

  • 20. Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E.
    Mahrhold S, Strotmeier J, Garcia-Rodriguez C, Lou J, Marks JD, Rummel A, Binz T.
    Biochem J; 2013 Jul 01; 453(1):37-47. PubMed ID: 23621114
    [Abstract] [Full Text] [Related]


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