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109 related items for PubMed ID: 27211603

  • 1. Assessment of placental transfer and the effect on embryo-fetal development of a humanized monoclonal antibody targeting lymphotoxin-alpha in non-human primates.
    Wang H, Schuetz C, Arima A, Chihaya Y, Weinbauer GF, Habermann G, Xiao J, Woods C, Grogan J, Gelzleichter T, Cain G.
    Reprod Toxicol; 2016 Aug; 63():82-95. PubMed ID: 27211603
    [Abstract] [Full Text] [Related]

  • 2. Farletuzumab, a monoclonal antibody directed against folate receptor alpha, shows no evidence of teratogenicity in cynomolgus monkeys.
    Moriyama T, Kakiuchi D, Grasso L, Hutto DL, Fernando D, Schweizer C.
    Reprod Toxicol; 2018 Aug; 79():89-95. PubMed ID: 29928988
    [Abstract] [Full Text] [Related]

  • 3. An Enhanced Pre- and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody.
    Breslin WJ, Hilbish KG, Martin JA, Halstead CA, Newcomb DL, Chellman GJ.
    Birth Defects Res B Dev Reprod Toxicol; 2015 Jun; 104(3):100-16. PubMed ID: 26195230
    [Abstract] [Full Text] [Related]

  • 4. Pre- and postnatal development in the cynomolgus monkey following administration of ABT-874, a human anti-IL-12/23p40 monoclonal antibody.
    Enright BP, Tornesi B, Weinbauer GF, Blaich G.
    Birth Defects Res B Dev Reprod Toxicol; 2012 Dec; 95(6):431-43. PubMed ID: 23212752
    [Abstract] [Full Text] [Related]

  • 5. Placental transfer of a fully human IgG2 monoclonal antibody in the cynomolgus monkey, rat, and rabbit: a comparative assessment from during organogenesis to late gestation.
    Moffat GJ, Retter MW, Kwon G, Loomis M, Hock MB, Hall C, Bussiere J, Lewis EM, Chellman GJ.
    Birth Defects Res B Dev Reprod Toxicol; 2014 Apr; 101(2):178-88. PubMed ID: 24753333
    [Abstract] [Full Text] [Related]

  • 6. Embryo-fetal distribution of a biopharmaceutical IgG2 during rat organogenesis.
    Bowman CJ, King LE, Stedman DB.
    Reprod Toxicol; 2012 Aug; 34(1):66-72. PubMed ID: 22543284
    [Abstract] [Full Text] [Related]

  • 7. Placental transfer of Fc-containing biopharmaceuticals across species, an industry survey analysis.
    Bowman CJ, Breslin WJ, Connor AV, Martin PL, Moffat GJ, Sivaraman L, Tornesi MB, Chivers S.
    Birth Defects Res B Dev Reprod Toxicol; 2013 Dec; 98(6):459-85. PubMed ID: 24391099
    [Abstract] [Full Text] [Related]

  • 8. Placental transfer of (125)Iodinated humanized immunoglobulin G2Δa in the Sprague Dawley rat.
    Coder PS, Thomas JA, Stedman DB, Bowman CJ.
    Reprod Toxicol; 2013 Jul; 38():37-46. PubMed ID: 23462583
    [Abstract] [Full Text] [Related]

  • 9. Placental transfer of 125 iodinated humanized immunoglobulin G2Δa in the cynomolgus monkey.
    Catlin NR, Mitchell AZ, Potchoiba MJ, O'Hara DM, Wang M, Zhang M, Weinbauer GF, Bowman CJ.
    Birth Defects Res; 2020 Jan 01; 112(1):105-117. PubMed ID: 31746560
    [Abstract] [Full Text] [Related]

  • 10. Developmental immunotoxicology assessment of rituximab in cynomolgus monkeys.
    Vaidyanathan A, McKeever K, Anand B, Eppler S, Weinbauer GF, Beyer JC.
    Toxicol Sci; 2011 Jan 01; 119(1):116-25. PubMed ID: 20937725
    [Abstract] [Full Text] [Related]

  • 11. Effects of SA237, a humanized anti-interleukin-6 receptor monoclonal antibody, on pre- and postnatal development in cynomolgus monkey.
    Katagiri R, Ishihara-Hattori K, Frings W, Amano J, Fuchs A, Chiba S.
    Birth Defects Res; 2017 Jul 03; 109(11):843-856. PubMed ID: 28504465
    [Abstract] [Full Text] [Related]

  • 12. Developmental toxicity assessment of tanezumab, an anti-nerve growth factor monoclonal antibody, in cynomolgus monkeys (Macaca fascicularis).
    Bowman CJ, Evans M, Cummings T, Oneda S, Butt M, Hurst S, Gremminger JL, Shelton D, Kamperschroer C, Zorbas M.
    Reprod Toxicol; 2015 Jun 03; 53():105-18. PubMed ID: 25461901
    [Abstract] [Full Text] [Related]

  • 13. Nonclinical safety of tildrakizumab, a humanized anti-IL-23p19 monoclonal antibody, in nonhuman primates.
    Santostefano M, Herzyk D, Montgomery D, Wolf J.
    Regul Toxicol Pharmacol; 2019 Nov 03; 108():104476. PubMed ID: 31536773
    [Abstract] [Full Text] [Related]

  • 14. Reproductive toxicity of denosumab in cynomolgus monkeys.
    Bussiere JL, Pyrah I, Boyce R, Branstetter D, Loomis M, Andrews-Cleavenger D, Farman C, Elliott G, Chellman G.
    Reprod Toxicol; 2013 Dec 03; 42():27-40. PubMed ID: 23886817
    [Abstract] [Full Text] [Related]

  • 15. TGF-β1 monoclonal antibody: Assessment of embryo-fetal toxicity in rats and rabbits.
    Hilbish KG, Martin JA, Stauber AJ, Edwards TL, Breslin WJ.
    Birth Defects Res B Dev Reprod Toxicol; 2016 Aug 03; 107(4-5):174-184. PubMed ID: 27519584
    [Abstract] [Full Text] [Related]

  • 16. Embryo-fetal developmental toxicity of figitumumab, an anti-insulin-like growth factor-1 receptor (IGF-1R) monoclonal antibody, in cynomolgus monkeys.
    Bowman CJ, Chmielewski G, Oneda S, Finco D, Boucher MA, Todd M.
    Birth Defects Res B Dev Reprod Toxicol; 2010 Aug 03; 89(4):326-38. PubMed ID: 20540090
    [Abstract] [Full Text] [Related]

  • 17. Evaluation of the Developmental Toxicity of Vedolizumab, an α4β7 Receptor Antagonist, in Rabbit and Nonhuman Primate.
    Crawford D, Friedman M.
    Int J Toxicol; 2019 Aug 03; 38(5):395-404. PubMed ID: 31364424
    [Abstract] [Full Text] [Related]

  • 18. PDGFRα monoclonal antibody: Assessment of embryo-fetal toxicity and time-dependent placental transfer of a murine surrogate antibody of olaratumab in mice.
    Luffer-Atlas D, Reddy VR, Hilbish KG, Grace CE, Breslin WJ.
    Birth Defects Res; 2018 Nov 01; 110(18):1358-1371. PubMed ID: 30367709
    [Abstract] [Full Text] [Related]

  • 19. Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody.
    Breslin WJ, Hilbish KG, Martin JA, Halstead CA, Edwards TL.
    Birth Defects Res B Dev Reprod Toxicol; 2015 Jun 01; 104(3):117-28. PubMed ID: 26195315
    [Abstract] [Full Text] [Related]

  • 20. Assessment of ixekizumab, an interleukin-17A monoclonal antibody, for potential effects on reproduction and development, including immune system function, in cynomolgus monkeys.
    Clarke DO, Hilbish KG, Waters DG, Newcomb DL, Chellman GJ.
    Reprod Toxicol; 2015 Dec 01; 58():160-73. PubMed ID: 26482726
    [Abstract] [Full Text] [Related]

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