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Journal Abstract Search

577 related items for PubMed ID: 27213815

  • 1. A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
    Dauch D, Rudalska R, Cossa G, Nault JC, Kang TW, Wuestefeld T, Hohmeyer A, Imbeaud S, Yevsa T, Hoenicke L, Pantsar T, Bozko P, Malek NP, Longerich T, Laufer S, Poso A, Zucman-Rossi J, Eilers M, Zender L.
    Nat Med; 2016 Jul; 22(7):744-53. PubMed ID: 27213815
    [Abstract] [Full Text] [Related]

  • 2. Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice.
    Song CQ, Li Y, Mou H, Moore J, Park A, Pomyen Y, Hough S, Kennedy Z, Fischer A, Yin H, Anderson DG, Conte D, Zender L, Wang XW, Thorgeirsson S, Weng Z, Xue W.
    Gastroenterology; 2017 Apr; 152(5):1161-1173.e1. PubMed ID: 27956228
    [Abstract] [Full Text] [Related]

  • 3. c-Myc Is a Major Determinant for Antitumor Activity of Aurora A Kinase Inhibitor MLN8237 in Thyroid Cancer.
    Li Y, Li X, Pu J, Yang Q, Guan H, Ji M, Shi B, Chen M, Hou P.
    Thyroid; 2018 Dec; 28(12):1642-1654. PubMed ID: 30226440
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Wang NJ, Zhao RJ, Zhou SF.
    Drug Des Devel Ther; 2015 Dec; 9():487-508. PubMed ID: 25609923
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
    Wang-Bishop L, Chen Z, Gomaa A, Lockhart AC, Salaria S, Wang J, Lewis KB, Ecsedy J, Washington K, Beauchamp RD, El-Rifai W.
    Gastroenterology; 2019 Feb; 156(3):662-675.e7. PubMed ID: 30342037
    [Abstract] [Full Text] [Related]

  • 6. Aurora kinase A mediates c-Myc's oncogenic effects in hepatocellular carcinoma.
    Lu L, Han H, Tian Y, Li W, Zhang J, Feng M, Li Y.
    Mol Carcinog; 2015 Nov; 54(11):1467-79. PubMed ID: 25284017
    [Abstract] [Full Text] [Related]

  • 7. Quantitative Proteomics Reveals That the Inhibition of Na(+)/K(+)-ATPase Activity Affects S-Phase Progression Leading to a Chromosome Segregation Disorder by Attenuating the Aurora A Function in Hepatocellular Carcinoma Cells.
    Xu Z, Wang F, Fan F, Gu Y, Shan N, Meng X, Cheng S, Liu Y, Wang C, Song Y, Xu R.
    J Proteome Res; 2015 Nov 06; 14(11):4594-602. PubMed ID: 26491887
    [Abstract] [Full Text] [Related]

  • 8. Overcoming MITF-conferred drug resistance through dual AURKA/MAPK targeting in human melanoma cells.
    Pathria G, Garg B, Borgdorff V, Garg K, Wagner C, Superti-Furga G, Wagner SN.
    Cell Death Dis; 2016 Mar 10; 7(3):e2135. PubMed ID: 26962685
    [Abstract] [Full Text] [Related]

  • 9. Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma.
    Romain C, Paul P, Kim KW, Lee S, Qiao J, Chung DH.
    J Pediatr Surg; 2014 Jan 10; 49(1):159-65. PubMed ID: 24439602
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines.
    Liu N, Wang YA, Sun Y, Ecsedy J, Sun J, Li X, Wang P.
    Respir Res; 2019 Oct 23; 20(1):230. PubMed ID: 31647033
    [Abstract] [Full Text] [Related]

  • 11. ID1 overexpression promotes HCC progression by amplifying the AURKA/Myc signaling pathway.
    Wu M, Zhou Y, Fei C, Chen T, Yin X, Zhang L, Ren Z.
    Int J Oncol; 2020 Sep 23; 57(3):845-857. PubMed ID: 32705157
    [Abstract] [Full Text] [Related]

  • 12. Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.
    Ding YH, Zhou ZW, Ha CF, Zhang XY, Pan ST, He ZX, Edelman JL, Wang D, Yang YX, Zhang X, Duan W, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Sep 23; 9():425-64. PubMed ID: 25624750
    [Abstract] [Full Text] [Related]

  • 13. Dual BRD4 and AURKA Inhibition Is Synergistic against MYCN-Amplified and Nonamplified Neuroblastoma.
    Felgenhauer J, Tomino L, Selich-Anderson J, Bopp E, Shah N.
    Neoplasia; 2018 Oct 23; 20(10):965-974. PubMed ID: 30153557
    [Abstract] [Full Text] [Related]

  • 14. PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc.
    Boi D, Souvalidou F, Capelli D, Polverino F, Marini G, Montanari R, Pochetti G, Tramonti A, Contestabile R, Trisciuoglio D, Carpinelli P, Ascanelli C, Lindon C, De Leo A, Saviano M, Di Santo R, Costi R, Guarguaglini G, Paiardini A.
    Int J Mol Sci; 2021 Dec 04; 22(23):. PubMed ID: 34884931
    [Abstract] [Full Text] [Related]

  • 15. Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck.
    Lee JW, Parameswaran J, Sandoval-Schaefer T, Eoh KJ, Yang DH, Zhu F, Mehra R, Sharma R, Gaffney SG, Perry EB, Townsend JP, Serebriiskii IG, Golemis EA, Issaeva N, Yarbrough WG, Koo JS, Burtness B.
    Clin Cancer Res; 2019 Jun 01; 25(11):3430-3442. PubMed ID: 30755439
    [Abstract] [Full Text] [Related]

  • 16. Aurora kinase targeting in lung cancer reduces KRAS-induced transformation.
    Dos Santos EO, Carneiro-Lobo TC, Aoki MN, Levantini E, Bassères DS.
    Mol Cancer; 2016 Feb 03; 15():12. PubMed ID: 26842935
    [Abstract] [Full Text] [Related]

  • 17. Activation of EIF4E by Aurora Kinase A Depicts a Novel Druggable Axis in Everolimus-Resistant Cancer Cells.
    Katsha A, Wang L, Arras J, Omar OM, Ecsedy J, Belkhiri A, El-Rifai W.
    Clin Cancer Res; 2017 Jul 15; 23(14):3756-3768. PubMed ID: 28073841
    [Abstract] [Full Text] [Related]

  • 18. HDM2 regulation by AURKA promotes cell survival in gastric cancer.
    Sehdev V, Katsha A, Arras J, Peng D, Soutto M, Ecsedy J, Zaika A, Belkhiri A, El-Rifai W.
    Clin Cancer Res; 2014 Jan 01; 20(1):76-86. PubMed ID: 24240108
    [Abstract] [Full Text] [Related]

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