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Journal Abstract Search

578 related items for PubMed ID: 27218270

  • 1. PCSK9 R46L Loss-of-Function Mutation Reduces Lipoprotein(a), LDL Cholesterol, and Risk of Aortic Valve Stenosis.
    Langsted A, Nordestgaard BG, Benn M, Tybjærg-Hansen A, Kamstrup PR.
    J Clin Endocrinol Metab; 2016 Sep; 101(9):3281-7. PubMed ID: 27218270
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  • 2. PCSK9 R46L, lower LDL, and cardiovascular disease risk in familial hypercholesterolemia: a cross-sectional cohort study.
    Saavedra YG, Dufour R, Davignon J, Baass A.
    Arterioscler Thromb Vasc Biol; 2014 Dec; 34(12):2700-5. PubMed ID: 25278291
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  • 7. Loss-of-function mutation R46L in the PCSK9 gene has little impact on the levels of total serum cholesterol in familial hypercholesterolemia heterozygotes.
    Strøm TB, Holla ØL, Cameron J, Berge KE, Leren TP.
    Clin Chim Acta; 2010 Feb; 411(3-4):229-33. PubMed ID: 19917273
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  • 8. R46L polymorphism in the PCSK9 gene: Relationship to lipid levels, subclinical vascular disease, and erectile dysfunction.
    Mostaza JM, Lahoz C, Salinero-Fort MA, de Dios O, Castillo E, González-Alegre T, García-Iglesias F, Estirado E, Laguna F, Sabín C, López S, Cornejo V, de Burgos C, Sanchez V, Garcés C, investigators of the SPREDIA-2 Group.
    J Clin Lipidol; 2018 Feb; 12(4):1039-1046.e3. PubMed ID: 29773421
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  • 9. Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study.
    Benn M, Nordestgaard BG, Frikke-Schmidt R, Tybjærg-Hansen A.
    BMJ; 2017 Apr 24; 357():j1648. PubMed ID: 28438747
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  • 12. Effects of PCSK9 genetic variants on plasma LDL cholesterol levels and risk of premature myocardial infarction in the Italian population.
    Guella I, Asselta R, Ardissino D, Merlini PA, Peyvandi F, Kathiresan S, Mannucci PM, Tubaro M, Duga S.
    J Lipid Res; 2010 Nov 24; 51(11):3342-9. PubMed ID: 20699424
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  • 13. Both rare and common variants in PCSK9 influence plasma low-density lipoprotein cholesterol level in American Indians.
    Tsai CW, North KE, Tin A, Haack K, Franceschini N, Saroja Voruganti V, Laston S, Zhang Y, Best LG, MacCluer JW, Beaty TH, Navas-Acien A, Kao WH, Howard BV.
    J Clin Endocrinol Metab; 2015 Feb 24; 100(2):E345-9. PubMed ID: 25412415
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  • 14. AMG145, a monoclonal antibody against proprotein convertase subtilisin kexin type 9, significantly reduces lipoprotein(a) in hypercholesterolemic patients receiving statin therapy: an analysis from the LDL-C Assessment with Proprotein Convertase Subtilisin Kexin Type 9 Monoclonal Antibody Inhibition Combined with Statin Therapy (LAPLACE)-Thrombolysis in Myocardial Infarction (TIMI) 57 trial.
    Desai NR, Kohli P, Giugliano RP, O'Donoghue ML, Somaratne R, Zhou J, Hoffman EB, Huang F, Rogers WJ, Wasserman SM, Scott R, Sabatine MS.
    Circulation; 2013 Aug 27; 128(9):962-9. PubMed ID: 23884353
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  • 16. Predicting proprotein convertase subtilisin kexin type-9 loss of function mutations using plasma PCSK9 concentration.
    Wanneh E, Luna G, Dufour R, Baass A.
    J Clin Lipidol; 2017 Aug 27; 11(1):55-60. PubMed ID: 28391911
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  • 20. The PCSK9 gene R46L variant is associated with lower plasma lipid levels and cardiovascular risk in healthy U.K. men.
    Scartezini M, Hubbart C, Whittall RA, Cooper JA, Neil AH, Humphries SE.
    Clin Sci (Lond); 2007 Dec 27; 113(11):435-41. PubMed ID: 17550346
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