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139 related items for PubMed ID: 27229336

  • 1. Inhibition of tyrosine phenol-lyase by tyrosine homologues.
    Do Q, Nguyen GT, Phillips RS.
    Amino Acids; 2016 Sep; 48(9):2243-51. PubMed ID: 27229336
    [Abstract] [Full Text] [Related]

  • 2. The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity.
    Sundararaju B, Antson AA, Phillips RS, Demidkina TV, Barbolina MV, Gollnick P, Dodson GG, Wilson KS.
    Biochemistry; 1997 May 27; 36(21):6502-10. PubMed ID: 9174368
    [Abstract] [Full Text] [Related]

  • 3. Aminoacrylate intermediates in the reaction of Citrobacter freundii tyrosine phenol-lyase.
    Phillips RS, Chen HY, Faleev NG.
    Biochemistry; 2006 Aug 08; 45(31):9575-83. PubMed ID: 16878992
    [Abstract] [Full Text] [Related]

  • 4. Citrobacter freundii tyrosine phenol-lyase: the role of asparagine 185 in modulating enzyme function through stabilization of a quinonoid intermediate.
    Barbolina MV, Phillips RS, Gollnick PD, Faleev NG, Demidkina TV.
    Protein Eng; 2000 Mar 08; 13(3):207-15. PubMed ID: 10775663
    [Abstract] [Full Text] [Related]

  • 5. Role of lysine-256 in Citrobacter freundii tyrosine phenol-lyase in monovalent cation activation.
    Phillips RS, Chen HY, Shim D, Lima S, Tavakoli K, Sundararaju B.
    Biochemistry; 2004 Nov 16; 43(45):14412-9. PubMed ID: 15533046
    [Abstract] [Full Text] [Related]

  • 6. Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes.
    Phillips RS, Demidkina TV, Zakomirdina LN, Bruno S, Ronda L, Mozzarelli A.
    J Biol Chem; 2002 Jun 14; 277(24):21592-7. PubMed ID: 11934889
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of tyrosine phenol-lyase from Citrobacter freundii by 2-azatyrosine and 3-azatyrosine.
    Watkins EB, Phillips RS.
    Biochemistry; 2001 Dec 11; 40(49):14862-8. PubMed ID: 11732906
    [Abstract] [Full Text] [Related]

  • 8. Effects of tyrosine ring fluorination on rates and equilibria of formation of intermediates in the reactions of carbon-carbon lyases.
    Phillips RS, Von Tersch RL, Secundo F.
    Eur J Biochem; 1997 Mar 01; 244(2):658-63. PubMed ID: 9119037
    [Abstract] [Full Text] [Related]

  • 9. Crystal Structures of Wild-Type and F448A Mutant Citrobacter freundii Tyrosine Phenol-Lyase Complexed with a Substrate and Inhibitors: Implications for the Reaction Mechanism.
    Phillips RS, Craig S.
    Biochemistry; 2018 Oct 30; 57(43):6166-6179. PubMed ID: 30260636
    [Abstract] [Full Text] [Related]

  • 10. Stereospecificity of isotopic exchange of C-α-protons of glycine catalyzed by three PLP-dependent lyases: the unusual case of tyrosine phenol-lyase.
    Koulikova VV, Zakomirdina LN, Gogoleva OI, Tsvetikova MA, Morozova EA, Komissarov VV, Tkachev YV, Timofeev VP, Demidkina TV, Faleev NG.
    Amino Acids; 2011 Nov 30; 41(5):1247-56. PubMed ID: 21104284
    [Abstract] [Full Text] [Related]

  • 11. The role of glutamic acid-69 in the activation of Citrobacter freundii tyrosine phenol-lyase by monovalent cations.
    Sundararaju B, Chen H, Shilcutt S, Phillips RS.
    Biochemistry; 2000 Jul 25; 39(29):8546-55. PubMed ID: 10913261
    [Abstract] [Full Text] [Related]

  • 12. The role of substrate strain in the mechanism of the carbon-carbon lyases.
    Phillips RS, Demidkina TV, Faleev NG.
    Bioorg Chem; 2014 Dec 25; 57():198-205. PubMed ID: 25035301
    [Abstract] [Full Text] [Related]

  • 13. Site-directed mutagenesis of tyrosine-71 to phenylalanine in Citrobacter freundii tyrosine phenol-lyase: evidence for dual roles of tyrosine-71 as a general acid catalyst in the reaction mechanism and in cofactor binding.
    Chen HY, Demidkina TV, Phillips RS.
    Biochemistry; 1995 Sep 26; 34(38):12276-83. PubMed ID: 7547970
    [Abstract] [Full Text] [Related]

  • 14. Site-directed mutagenesis of His343-->Ala in Citrobacter freundii tyrosine phenol-lyase. Effects on the kinetic mechanism and rate-determining step.
    Chen H, Gollnick P, Phillips RS.
    Eur J Biochem; 1995 Apr 15; 229(2):540-9. PubMed ID: 7744078
    [Abstract] [Full Text] [Related]

  • 15. Aspartic acid 214 in Citrobacter freundii tyrosine phenol-lyase ensures sufficient C--H-acidity of the external aldimine intermediate and proper orientation of the cofactor at the active site.
    Demidkina TV, Faleev NG, Papisova AI, Bazhulina NP, Kulikova VV, Gollnick PD, Phillips RS.
    Biochim Biophys Acta; 2006 Jul 15; 1764(7):1268-76. PubMed ID: 16793353
    [Abstract] [Full Text] [Related]

  • 16. M379A Mutant Tyrosine Phenol-lyase from Citrobacter freundii Has Altered Conformational Dynamics.
    Phillips RS, Jones B, Nash S.
    Chembiochem; 2022 Jul 05; 23(13):e202200028. PubMed ID: 35577764
    [Abstract] [Full Text] [Related]

  • 17. Serine 51 residue of Citrobacter freundii tyrosine phenol-lyase assists in C-α-proton abstraction and transfer in the reaction with substrate.
    Barbolina MV, Kulikova VV, Tsvetikova MA, Anufrieva NV, Revtovich SV, Phillips RS, Gollnick PD, Demidkina TV, Faleev NG.
    Biochimie; 2018 Apr 05; 147():63-69. PubMed ID: 29183854
    [Abstract] [Full Text] [Related]

  • 18. Tyrosine phenol-lyase and tryptophan indole-lyase encapsulated in wet nanoporous silica gels: Selective stabilization of tertiary conformations.
    Pioselli B, Bettati S, Demidkina TV, Zakomirdina LN, Phillips RS, Mozzarelli A.
    Protein Sci; 2004 Apr 05; 13(4):913-24. PubMed ID: 15044726
    [Abstract] [Full Text] [Related]

  • 19. Threonine-124 and phenylalanine-448 in Citrobacter freundii tyrosine phenol-lyase are necessary for activity with L-tyrosine.
    Demidkina TV, Barbolina MV, Faleev NG, Sundararaju B, Gollnick PD, Phillips RS.
    Biochem J; 2002 May 01; 363(Pt 3):745-52. PubMed ID: 11964175
    [Abstract] [Full Text] [Related]

  • 20. Binding of phenol and analogues to alanine complexes of tyrosine phenol-lyase from Citrobacter freundii: implications for the mechanisms of alpha,beta-elimination and alanine racemization.
    Chen H, Phillips RS.
    Biochemistry; 1993 Nov 02; 32(43):11591-9. PubMed ID: 8218227
    [Abstract] [Full Text] [Related]

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