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Journal Abstract Search

416 related items for PubMed ID: 27238637

  • 1. Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.
    Titchenell PM, Quinn WJ, Lu M, Chu Q, Lu W, Li C, Chen H, Monks BR, Chen J, Rabinowitz JD, Birnbaum MJ.
    Cell Metab; 2016 Jun 14; 23(6):1154-1166. PubMed ID: 27238637
    [Abstract] [Full Text] [Related]

  • 2. Amino Acids Attenuate Insulin Action on Gluconeogenesis and Promote Fatty Acid Biosynthesis via mTORC1 Signaling Pathway in trout Hepatocytes.
    Dai W, Panserat S, Plagnes-Juan E, Seiliez I, Skiba-Cassy S.
    Cell Physiol Biochem; 2015 Jun 14; 36(3):1084-100. PubMed ID: 26112996
    [Abstract] [Full Text] [Related]

  • 3. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
    Hagiwara A, Cornu M, Cybulski N, Polak P, Betz C, Trapani F, Terracciano L, Heim MH, Rüegg MA, Hall MN.
    Cell Metab; 2012 May 02; 15(5):725-38. PubMed ID: 22521878
    [Abstract] [Full Text] [Related]

  • 4. Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation.
    Kenerson HL, Yeh MM, Yeung RS.
    PLoS One; 2011 Mar 29; 6(3):e18075. PubMed ID: 21479224
    [Abstract] [Full Text] [Related]

  • 5. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
    Sajan MP, Ivey RA, Lee MC, Farese RV.
    J Lipid Res; 2015 Jan 29; 56(1):70-80. PubMed ID: 25395359
    [Abstract] [Full Text] [Related]

  • 6. Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.
    Sajan MP, Lee MC, Foufelle F, Sajan J, Cleland C, Farese RV.
    Cell Signal; 2018 Mar 29; 43():62-70. PubMed ID: 29269047
    [Abstract] [Full Text] [Related]

  • 7. Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling.
    Zhang D, Tong X, Arthurs B, Guha A, Rui L, Kamath A, Inoki K, Yin L.
    J Biol Chem; 2014 Sep 12; 289(37):25925-35. PubMed ID: 25063808
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability.
    Pajvani UB, Qiang L, Kangsamaksin T, Kitajewski J, Ginsberg HN, Accili D.
    Nat Med; 2013 Aug 12; 19(8):1054-60. PubMed ID: 23832089
    [Abstract] [Full Text] [Related]

  • 9. The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver.
    Hörbelt T, Knebel B, Fahlbusch P, Barbosa D, de Wiza DH, Van de Velde F, Van Nieuwenhove Y, Lapauw B, Thoresen GH, Al-Hasani H, Müller-Wieland D, Ouwens DM, Kotzka J.
    Biochim Biophys Acta Mol Basis Dis; 2019 Oct 01; 1865(10):2671-2684. PubMed ID: 31336149
    [Abstract] [Full Text] [Related]

  • 10. Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis.
    Li S, Brown MS, Goldstein JL.
    Proc Natl Acad Sci U S A; 2010 Feb 23; 107(8):3441-6. PubMed ID: 20133650
    [Abstract] [Full Text] [Related]

  • 11. Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.
    Wan M, Leavens KF, Saleh D, Easton RM, Guertin DA, Peterson TR, Kaestner KH, Sabatini DM, Birnbaum MJ.
    Cell Metab; 2011 Oct 05; 14(4):516-27. PubMed ID: 21982711
    [Abstract] [Full Text] [Related]

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  • 13. Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways.
    Yecies JL, Zhang HH, Menon S, Liu S, Yecies D, Lipovsky AI, Gorgun C, Kwiatkowski DJ, Hotamisligil GS, Lee CH, Manning BD.
    Cell Metab; 2011 Jul 06; 14(1):21-32. PubMed ID: 21723501
    [Abstract] [Full Text] [Related]

  • 14. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
    Tang Y, Wallace M, Sanchez-Gurmaches J, Hsiao WY, Li H, Lee PL, Vernia S, Metallo CM, Guertin DA.
    Nat Commun; 2016 Apr 21; 7():11365. PubMed ID: 27098609
    [Abstract] [Full Text] [Related]

  • 15. Hepatic p38α MAPK controls gluconeogenesis via FOXO1 phosphorylation at S273 during glucagon signalling in mice.
    Yang W, Liao W, Li X, Ai W, Pan Q, Shen Z, Jiang W, Guo S.
    Diabetologia; 2023 Jul 21; 66(7):1322-1339. PubMed ID: 37202506
    [Abstract] [Full Text] [Related]

  • 16. A bioinformatics and transcriptomics based investigation reveals an inhibitory role of Huanglian-Renshen-Decoction on hepatic glucose production of T2DM mice via PI3K/Akt/FoxO1 signaling pathway.
    Wu F, Shao Q, Xia Q, Hu M, Zhao Y, Wang D, Fang K, Xu L, Zou X, Chen Z, Chen G, Lu F.
    Phytomedicine; 2021 Mar 21; 83():153487. PubMed ID: 33636476
    [Abstract] [Full Text] [Related]

  • 17. Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.
    Liu TY, Shi CX, Gao R, Sun HJ, Xiong XQ, Ding L, Chen Q, Li YH, Wang JJ, Kang YM, Zhu GQ.
    Clin Sci (Lond); 2015 Nov 21; 129(10):839-50. PubMed ID: 26201094
    [Abstract] [Full Text] [Related]

  • 18. Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt.
    Kenerson HL, Subramanian S, McIntyre R, Kazami M, Yeung RS.
    PLoS One; 2015 Nov 21; 10(2):e0117000. PubMed ID: 25646773
    [Abstract] [Full Text] [Related]

  • 19. Long Noncoding RNA lncSHGL Recruits hnRNPA1 to Suppress Hepatic Gluconeogenesis and Lipogenesis.
    Wang J, Yang W, Chen Z, Chen J, Meng Y, Feng B, Sun L, Dou L, Li J, Cui Q, Yang J.
    Diabetes; 2018 Apr 21; 67(4):581-593. PubMed ID: 29382663
    [Abstract] [Full Text] [Related]

  • 20. Post-prandial regulation of hepatic glucokinase and lipogenesis requires the activation of TORC1 signalling in rainbow trout (Oncorhynchus mykiss).
    Dai W, Panserat S, Mennigen JA, Terrier F, Dias K, Seiliez I, Skiba-Cassy S.
    J Exp Biol; 2013 Dec 01; 216(Pt 23):4483-92. PubMed ID: 24031053
    [Abstract] [Full Text] [Related]

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