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1159 related items for PubMed ID: 27245569

  • 1. Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization.
    Ali SM, Hensing T, Schrock AB, Allen J, Sanford E, Gowen K, Kulkarni A, He J, Suh JH, Lipson D, Elvin JA, Yelensky R, Chalmers Z, Chmielecki J, Peled N, Klempner SJ, Firozvi K, Frampton GM, Molina JR, Menon S, Brahmer JR, MacMahon H, Nowak J, Ou SH, Zauderer M, Ladanyi M, Zakowski M, Fischbach N, Ross JS, Stephens PJ, Miller VA, Wakelee H, Ganesan S, Salgia R.
    Oncologist; 2016 Jun; 21(6):762-70. PubMed ID: 27245569
    [Abstract] [Full Text] [Related]

  • 2. Combinational Analysis of FISH and Immunohistochemistry Reveals Rare Genomic Events in ALK Fusion Patterns in NSCLC that Responds to Crizotinib Treatment.
    Li W, Zhang J, Guo L, Chuai S, Shan L, Ying J.
    J Thorac Oncol; 2017 Jan; 12(1):94-101. PubMed ID: 27614248
    [Abstract] [Full Text] [Related]

  • 3. EML4-ALK Fusion Detected by RT-PCR Confers Similar Response to Crizotinib as Detected by FISH in Patients with Advanced Non-Small-Cell Lung Cancer.
    Wang Y, Zhang J, Gao G, Li X, Zhao C, He Y, Su C, Zhang S, Chen X, Zhang J, Li W, Li B, Zhao J, Hou L, Wu C, Ren S, Zhou C, Zhang J.
    J Thorac Oncol; 2015 Nov; 10(11):1546-52. PubMed ID: 26352533
    [Abstract] [Full Text] [Related]

  • 4. ALK rearrangement in a large series of consecutive non-small cell lung cancers: comparison between a new immunohistochemical approach and fluorescence in situ hybridization for the screening of patients eligible for crizotinib treatment.
    Alì G, Proietti A, Pelliccioni S, Niccoli C, Lupi C, Sensi E, Giannini R, Borrelli N, Menghi M, Chella A, Ribechini A, Cappuzzo F, Melfi F, Lucchi M, Mussi A, Fontanini G.
    Arch Pathol Lab Med; 2014 Nov; 138(11):1449-58. PubMed ID: 24885803
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  • 5. ALK FISH patterns and the detection of ALK fusions by next generation sequencing in lung adenocarcinoma.
    Dacic S, Villaruz LC, Abberbock S, Mahaffey A, Incharoen P, Nikiforova MN.
    Oncotarget; 2016 Dec 13; 7(50):82943-82952. PubMed ID: 27769042
    [Abstract] [Full Text] [Related]

  • 6. Responses to crizotinib in patients with ALK-positive lung adenocarcinoma who tested immunohistochemistry (IHC)-positive and fluorescence in situ hybridization (FISH)-negative.
    Ma D, Wang Z, Yang L, Mu X, Wang Y, Zhao X, Li J, Lin D.
    Oncotarget; 2016 Sep 27; 7(39):64410-64420. PubMed ID: 27418132
    [Abstract] [Full Text] [Related]

  • 7. Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer.
    Nilsson RJ, Karachaliou N, Berenguer J, Gimenez-Capitan A, Schellen P, Teixido C, Tannous J, Kuiper JL, Drees E, Grabowska M, van Keulen M, Heideman DA, Thunnissen E, Dingemans AM, Viteri S, Tannous BA, Drozdowskyj A, Rosell R, Smit EF, Wurdinger T.
    Oncotarget; 2016 Jan 05; 7(1):1066-75. PubMed ID: 26544515
    [Abstract] [Full Text] [Related]

  • 8. ALK inhibitors in the treatment of advanced NSCLC.
    Gridelli C, Peters S, Sgambato A, Casaluce F, Adjei AA, Ciardiello F.
    Cancer Treat Rev; 2014 Mar 05; 40(2):300-6. PubMed ID: 23931927
    [Abstract] [Full Text] [Related]

  • 9. Detection of circulating tumor cells harboring a unique ALK rearrangement in ALK-positive non-small-cell lung cancer.
    Pailler E, Adam J, Barthélémy A, Oulhen M, Auger N, Valent A, Borget I, Planchard D, Taylor M, André F, Soria JC, Vielh P, Besse B, Farace F.
    J Clin Oncol; 2013 Jun 20; 31(18):2273-81. PubMed ID: 23669222
    [Abstract] [Full Text] [Related]

  • 10. Clinical Implications of Variant ALK FISH Rearrangement Patterns.
    Gao X, Sholl LM, Nishino M, Heng JC, Jänne PA, Oxnard GR.
    J Thorac Oncol; 2015 Nov 20; 10(11):1648-52. PubMed ID: 26536196
    [Abstract] [Full Text] [Related]

  • 11. Quantification of Anaplastic Lymphoma Kinase Protein Expression in Non-Small Cell Lung Cancer Tissues from Patients Treated with Crizotinib.
    Hembrough T, Liao WL, Hartley CP, Ma PC, Velcheti V, Lanigan C, Thyparambil S, An E, Monga M, Krizman D, Burrows J, Tafe LJ.
    Clin Chem; 2016 Jan 20; 62(1):252-61. PubMed ID: 26585927
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  • 15. U.S. Food and Drug Administration approval: crizotinib for treatment of advanced or metastatic non-small cell lung cancer that is anaplastic lymphoma kinase positive.
    Malik SM, Maher VE, Bijwaard KE, Becker RL, Zhang L, Tang SW, Song P, Liu Q, Marathe A, Gehrke B, Helms W, Hanner D, Justice R, Pazdur R.
    Clin Cancer Res; 2014 Apr 15; 20(8):2029-34. PubMed ID: 24573551
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  • 16. Automation of ALK gene rearrangement testing with fluorescence in situ hybridization (FISH): a feasibility study.
    Zwaenepoel K, Merkle D, Cabillic F, Berg E, Belaud-Rotureau MA, Grazioli V, Herelle O, Hummel M, Le Calve M, Lenze D, Mende S, Pauwels P, Quilichini B, Repetti E.
    Exp Mol Pathol; 2015 Feb 15; 98(1):113-8. PubMed ID: 25576649
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  • 17. Native and rearranged ALK copy number and rearranged cell count in non-small cell lung cancer: implications for ALK inhibitor therapy.
    Camidge DR, Skokan M, Kiatsimkul P, Helfrich B, Lu X, Barón AE, Schulte N, Maxson D, Aisner DL, Franklin WA, Doebele RC, Varella-Garcia M.
    Cancer; 2013 Nov 15; 119(22):3968-75. PubMed ID: 24022839
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