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278 related items for PubMed ID: 2725477

  • 1. Inhibition of oxidative drug metabolism by orphenadrine: in vitro and in vivo evidence for isozyme-specific complexation of cytochrome P-450 and inhibition kinetics.
    Reidy GF, Mehta I, Murray M.
    Mol Pharmacol; 1989 May; 35(5):736-43. PubMed ID: 2725477
    [Abstract] [Full Text] [Related]

  • 2. In vitro formation of an inhibitory complex between an isosafrole metabolite and rat hepatic cytochrome P-450 PB-B.
    Murray M, Reidy GF.
    Drug Metab Dispos; 1989 May; 17(4):449-54. PubMed ID: 2571488
    [Abstract] [Full Text] [Related]

  • 3. Biotransformation of N,N',N''-triethylenethiophosphoramide: oxidative desulfuration to yield N,N',N''-triethylenephosphoramide associated with suicide inactivation of a phenobarbital-inducible hepatic P-450 monooxygenase.
    Ng SF, Waxman DJ.
    Cancer Res; 1990 Feb 01; 50(3):464-71. PubMed ID: 2105156
    [Abstract] [Full Text] [Related]

  • 4. Identification of a reversible component in the in vitro inhibition of rat hepatic cytochrome P450 2B1 by parathion.
    Murray M, Butler AM.
    J Pharmacol Exp Ther; 1995 Feb 01; 272(2):639-44. PubMed ID: 7853177
    [Abstract] [Full Text] [Related]

  • 5. Interaction of constitutive and phenobarbital-induced cytochrome P-450 isozymes during the sequential oxidation of benzphetamine. Explanation for the difference in benzphetamine-induced hydrogen peroxide production and 455-nm complex formation in microsomes from untreated and phenobarbital-treated rats.
    Jeffery EH, Mannering GJ.
    Mol Pharmacol; 1983 May 01; 23(3):748-57. PubMed ID: 6865917
    [Abstract] [Full Text] [Related]

  • 6. Altered regulation of cytochrome P-450 enzymes in choline-deficient cirrhotic male rat liver: impaired regulation and activity of the male-specific androst-4-ene-3,17-dione 16 alpha-hydroxylase, cytochrome P-450UT-A, in hepatic cirrhosis.
    Murray M, Zaluzny L, Dannan GA, Guengerich FP, Farrell GC.
    Mol Pharmacol; 1987 Jan 01; 31(1):117-21. PubMed ID: 3543647
    [Abstract] [Full Text] [Related]

  • 7. Selective inactivation of four rat liver microsomal androstenedione hydroxylases by chloramphenicol analogs.
    Stevens JC, Halpert J.
    Mol Pharmacol; 1988 Jan 01; 33(1):103-10. PubMed ID: 3336347
    [Abstract] [Full Text] [Related]

  • 8. Product inhibition in orphenadrine metabolism as a result of a stable cytochrome P-450-metabolic intermediate complex formed during the disposition of mono-N-desmethylorphenadrine (tofenacine) in the rat.
    Bast A, van Kemenade FA, Savenije-Chapel EM, Noordhoek J.
    Res Commun Chem Pathol Pharmacol; 1983 Jun 01; 40(3):391-403. PubMed ID: 6622816
    [Abstract] [Full Text] [Related]

  • 9. Inhibition and induction of rabbit liver microsomal cytochrome P-450 by pyridine.
    Kaul KL, Novak RF.
    J Pharmacol Exp Ther; 1987 Oct 01; 243(1):384-90. PubMed ID: 3668864
    [Abstract] [Full Text] [Related]

  • 10. Selective inhibition of rat hepatic microsomal cytochrome P-450. I. Effect of the in vivo administration of cimetidine.
    Chang T, Levine M, Bandiera SM, Bellward GD.
    J Pharmacol Exp Ther; 1992 Mar 01; 260(3):1441-9. PubMed ID: 1545403
    [Abstract] [Full Text] [Related]

  • 11. Complexation of cytochrome P-450 isozymes in hepatic microsomes from SKF 525-A-induced rats.
    Murray M.
    Arch Biochem Biophys; 1988 May 01; 262(2):381-8. PubMed ID: 3364973
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of cytochrome P-450c-mediated benzo[a]pyrene hydroxylase and ethoxyresorufin O-deethylase by dihydrosafrole.
    Kao LR, Wilkinson CF.
    Xenobiotica; 1987 Jul 01; 17(7):793-805. PubMed ID: 3660849
    [Abstract] [Full Text] [Related]

  • 13. Immunochemical detection and quantitation of microsomal cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate:cytochrome P-450 reductase in the rat ventral prostate.
    Haaparanta T, Halpert J, Glaumann H, Gustafsson JA.
    Cancer Res; 1983 Nov 01; 43(11):5131-7. PubMed ID: 6413054
    [Abstract] [Full Text] [Related]

  • 14. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver.
    Amato G, Longo V, Mazzaccaro A, Gervasi PG.
    Chem Res Toxicol; 1996 Nov 01; 9(5):882-90. PubMed ID: 8828925
    [Abstract] [Full Text] [Related]

  • 15. Major isozymes of rat liver microsomal cytochrome P-450 involved in the N-oxidation of N-isopropyl-alpha-(2-methylazo)-p-toluamide, the azo derivative of procarbazine.
    Prough RA, Brown MI, Dannan GA, Guengerich FP.
    Cancer Res; 1984 Feb 01; 44(2):543-8. PubMed ID: 6692359
    [Abstract] [Full Text] [Related]

  • 16. Selective inactivation by chloramphenicol of the major phenobarbital-inducible isozyme of dog liver cytochrome P-450.
    Ciaccio PJ, Duignan DB, Halpert JR.
    Drug Metab Dispos; 1987 Feb 01; 15(6):852-6. PubMed ID: 2893713
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C, Gelboin HV, Park SS, Pearce R, Parkinson A, Kupfer D.
    Drug Metab Dispos; 1993 Feb 01; 21(4):645-56. PubMed ID: 8104124
    [Abstract] [Full Text] [Related]

  • 18. Mechanism-based inactivation of the major beta-naphthoflavone-inducible isozyme of rat liver cytochrome P-450 by the chloramphenicol analog N-(2-p-nitrophenethyl)dichloroacetamide.
    Miller NE, Halpert JR.
    Drug Metab Dispos; 1987 Feb 01; 15(6):846-51. PubMed ID: 2893712
    [Abstract] [Full Text] [Related]

  • 19. Suicide inactivation of cytochrome P-450 by methoxsalen. Evidence for the covalent binding of a reactive intermediate to the protein moiety.
    Labbe G, Descatoire V, Beaune P, Letteron P, Larrey D, Pessayre D.
    J Pharmacol Exp Ther; 1989 Sep 01; 250(3):1034-42. PubMed ID: 2506333
    [Abstract] [Full Text] [Related]

  • 20. [Evaluation of catalytic activity of multiple forms of cytochrome P-450 in liver microsomes of Wistar rats by androstenedione metabolism].
    Khatsenko OG, Guliaeva LF, Mishin VM, Liakhovich VV.
    Biokhimiia; 1990 Feb 01; 55(2):308-14. PubMed ID: 2340316
    [Abstract] [Full Text] [Related]

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