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178 related items for PubMed ID: 27256588

  • 1. An isoform of Nedd4-2 is critically involved in the renal adaptation to high salt intake in mice.
    Minegishi S, Ishigami T, Kino T, Chen L, Nakashima-Sasaki R, Araki N, Yatsu K, Fujita M, Umemura S.
    Sci Rep; 2016 Jun 03; 6():27137. PubMed ID: 27256588
    [Abstract] [Full Text] [Related]

  • 2. An Isoform of Nedd4-2 Plays a Pivotal Role in Electrophysiological Cardiac Abnormalities.
    Minegishi S, Ishigami T, Kawamura H, Kino T, Chen L, Nakashima-Sasaki R, Doi H, Azushima K, Wakui H, Chiba Y, Tamura K.
    Int J Mol Sci; 2017 Jun 14; 18(6):. PubMed ID: 28613240
    [Abstract] [Full Text] [Related]

  • 3. Eplerenone-Resistant Salt-Sensitive Hypertension in Nedd4-2 C2 KO Mice.
    Kino T, Ishigami T, Murata T, Doi H, Nakashima-Sasaki R, Chen L, Sugiyama M, Azushima K, Wakui H, Minegishi S, Tamura K.
    Int J Mol Sci; 2017 Jun 11; 18(6):. PubMed ID: 28604611
    [Abstract] [Full Text] [Related]

  • 4. Deletion of renal Nedd4-2 abolishes the effect of high sodium intake (HS) on Kir4.1, ENaC, and NCC and causes hypokalemia during high HS.
    Zhang DD, Duan XP, Xiao Y, Wu P, Gao ZX, Wang WH, Lin DH.
    Am J Physiol Renal Physiol; 2021 May 01; 320(5):F883-F896. PubMed ID: 33818128
    [Abstract] [Full Text] [Related]

  • 5. Salt-induced hypertension in a mouse model of Liddle syndrome is mediated by epithelial sodium channels in the brain.
    Van Huysse JW, Amin MS, Yang B, Leenen FH.
    Hypertension; 2012 Sep 01; 60(3):691-6. PubMed ID: 22802227
    [Abstract] [Full Text] [Related]

  • 6. ROMK channels are inhibited in the aldosterone-sensitive distal nephron of renal tubule Nedd4-2-deficient mice.
    Zhang DD, Zheng JY, Duan XP, Lin DH, Wang WH.
    Am J Physiol Renal Physiol; 2022 Jan 01; 322(1):F55-F67. PubMed ID: 34843409
    [Abstract] [Full Text] [Related]

  • 7. Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2.
    Shi PP, Cao XR, Sweezer EM, Kinney TS, Williams NR, Husted RF, Nair R, Weiss RM, Williamson RA, Sigmund CD, Snyder PM, Staub O, Stokes JB, Yang B.
    Am J Physiol Renal Physiol; 2008 Aug 01; 295(2):F462-70. PubMed ID: 18524855
    [Abstract] [Full Text] [Related]

  • 8. Deletion of Nedd4-2 results in progressive kidney disease in mice.
    Henshall TL, Manning JA, Alfassy OS, Goel P, Boase NA, Kawabe H, Kumar S.
    Cell Death Differ; 2017 Dec 01; 24(12):2150-2160. PubMed ID: 28862701
    [Abstract] [Full Text] [Related]

  • 9. Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension.
    Ronzaud C, Loffing-Cueni D, Hausel P, Debonneville A, Malsure SR, Fowler-Jaeger N, Boase NA, Perrier R, Maillard M, Yang B, Stokes JB, Koesters R, Kumar S, Hummler E, Loffing J, Staub O.
    J Clin Invest; 2013 Feb 01; 123(2):657-65. PubMed ID: 23348737
    [Abstract] [Full Text] [Related]

  • 10. Regulators of Epithelial Sodium Channels in Aldosterone-Sensitive Distal Nephrons (ASDN): Critical Roles of Nedd4L/Nedd4-2 and Salt-Sensitive Hypertension.
    Ishigami T, Kino T, Minegishi S, Araki N, Umemura M, Ushio H, Saigoh S, Sugiyama M.
    Int J Mol Sci; 2020 May 29; 21(11):. PubMed ID: 32485919
    [Abstract] [Full Text] [Related]

  • 11. A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain.
    Garrone NF, Blazer-Yost BL, Weiss RB, Lalouel JM, Rohrwasser A.
    BMC Cell Biol; 2009 Apr 13; 10():26. PubMed ID: 19364400
    [Abstract] [Full Text] [Related]

  • 12. NEDD4-2 and salt-sensitive hypertension.
    Rizzo F, Staub O.
    Curr Opin Nephrol Hypertens; 2015 Mar 13; 24(2):111-6. PubMed ID: 25602517
    [Abstract] [Full Text] [Related]

  • 13. C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.
    Zhu J, Lee KY, Jong TT, Tsai NP.
    J Neurochem; 2019 Nov 13; 151(3):289-300. PubMed ID: 31357244
    [Abstract] [Full Text] [Related]

  • 14. AMPK phosphorylation of the β1Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells.
    Ho PY, Li H, Cheng L, Bhalla V, Fenton RA, Hallows KR.
    Am J Physiol Renal Physiol; 2019 Dec 01; 317(6):F1513-F1525. PubMed ID: 31566435
    [Abstract] [Full Text] [Related]

  • 15. Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination.
    Staub O, Abriel H, Plant P, Ishikawa T, Kanelis V, Saleki R, Horisberger JD, Schild L, Rotin D.
    Kidney Int; 2000 Mar 01; 57(3):809-15. PubMed ID: 10720933
    [Abstract] [Full Text] [Related]

  • 16. Caffeine intake antagonizes salt sensitive hypertension through improvement of renal sodium handling.
    Yu H, Yang T, Gao P, Wei X, Zhang H, Xiong S, Lu Z, Li L, Wei X, Chen J, Zhao Y, Arendshorst WJ, Shang Q, Liu D, Zhu Z.
    Sci Rep; 2016 May 12; 6():25746. PubMed ID: 27173481
    [Abstract] [Full Text] [Related]

  • 17. Physiological Functions of Nedd4-2: Lessons from Knockout Mouse Models.
    Manning JA, Kumar S.
    Trends Biochem Sci; 2018 Aug 12; 43(8):635-647. PubMed ID: 30056838
    [Abstract] [Full Text] [Related]

  • 18. Liddle's syndrome: a novel mouse Nedd4 isoform regulates the activity of the epithelial Na(+) channel.
    Kamynina E, Debonneville C, Hirt RP, Staub O.
    Kidney Int; 2001 Aug 12; 60(2):466-71. PubMed ID: 11473628
    [Abstract] [Full Text] [Related]

  • 19. Dietary sodium modulates nephropathy in Nedd4-2-deficient mice.
    Manning JA, Shah SS, Henshall TL, Nikolic A, Finnie J, Kumar S.
    Cell Death Differ; 2020 Jun 12; 27(6):1832-1843. PubMed ID: 31802037
    [Abstract] [Full Text] [Related]

  • 20. NEDD4-2-dependent control of Na+ homeostasis and renal disease.
    Manning JA, Henshall TL, Kumar S.
    Cell Cycle; 2018 Jun 12; 17(1):1-2. PubMed ID: 29108451
    [No Abstract] [Full Text] [Related]

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