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Journal Abstract Search

350 related items for PubMed ID: 27320199

  • 1. Molecular Basis of Assembly and Activation of Complement Component C1 in Complex with Immunoglobulin G1 and Antigen.
    Wang G, de Jong RN, van den Bremer ET, Beurskens FJ, Labrijn AF, Ugurlar D, Gros P, Schuurman J, Parren PW, Heck AJ.
    Mol Cell; 2016 Jul 07; 63(1):135-45. PubMed ID: 27320199
    [Abstract] [Full Text] [Related]

  • 2. Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells.
    Tammen A, Derer S, Schwanbeck R, Rösner T, Kretschmer A, Beurskens FJ, Schuurman J, Parren PW, Valerius T.
    J Immunol; 2017 Feb 15; 198(4):1585-1594. PubMed ID: 28062698
    [Abstract] [Full Text] [Related]

  • 3. Anti-inflammatory activity of human IgA antibodies and their Fab alpha fragments: inhibition of IgG-mediated complement activation.
    Russell MW, Reinholdt J, Kilian M.
    Eur J Immunol; 1989 Dec 15; 19(12):2243-9. PubMed ID: 2606139
    [Abstract] [Full Text] [Related]

  • 4. Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen.
    Wang B, Yang C, Jin X, Du Q, Wu H, Dall'Acqua W, Mazor Y.
    MAbs; 2020 Dec 15; 12(1):1690959. PubMed ID: 31829766
    [Abstract] [Full Text] [Related]

  • 5. C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases.
    Zwarthoff SA, Widmer K, Kuipers A, Strasser J, Ruyken M, Aerts PC, de Haas CJC, Ugurlar D, den Boer MA, Vidarsson G, van Strijp JAG, Gros P, Parren PWHI, van Kessel KPM, Preiner J, Beurskens FJ, Schuurman J, Ricklin D, Rooijakkers SHM.
    Proc Natl Acad Sci U S A; 2021 Jun 29; 118(26):. PubMed ID: 34155115
    [Abstract] [Full Text] [Related]

  • 6. Potential of Murine IgG1 and Human IgG4 to Inhibit the Classical Complement and Fcγ Receptor Activation Pathways.
    Lilienthal GM, Rahmöller J, Petry J, Bartsch YC, Leliavski A, Ehlers M.
    Front Immunol; 2018 Jun 29; 9():958. PubMed ID: 29867943
    [Abstract] [Full Text] [Related]

  • 7. Complement is activated by IgG hexamers assembled at the cell surface.
    Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJ, van de Winkel JG, Wilson IA, Koster AJ, Taylor RP, Saphire EO, Burton DR, Schuurman J, Gros P, Parren PW.
    Science; 2014 Mar 14; 343(6176):1260-3. PubMed ID: 24626930
    [Abstract] [Full Text] [Related]

  • 8. Binding and complement activation by C-reactive protein via the collagen-like region of C1q and inhibition of these reactions by monoclonal antibodies to C-reactive protein and C1q.
    Jiang HX, Siegel JN, Gewurz H.
    J Immunol; 1991 Apr 01; 146(7):2324-30. PubMed ID: 2005402
    [Abstract] [Full Text] [Related]

  • 9. Influence of the hinge region on complement activation, C1q binding, and segmental flexibility in chimeric human immunoglobulins.
    Tan LK, Shopes RJ, Oi VT, Morrison SL.
    Proc Natl Acad Sci U S A; 1990 Jan 01; 87(1):162-6. PubMed ID: 2296577
    [Abstract] [Full Text] [Related]

  • 10. Atomic resolution model of the antibody Fc interaction with the complement C1q component.
    Schneider S, Zacharias M.
    Mol Immunol; 2012 May 01; 51(1):66-72. PubMed ID: 22425350
    [Abstract] [Full Text] [Related]

  • 11. Carbamylation reduces the capacity of IgG for hexamerization and complement activation.
    Lubbers R, Oostindie SC, Dijkstra DJ, Parren PWHI, Verheul MK, Abendstein L, Sharp TH, de Ru A, Janssen GMC, van Veelen PA, van den Bremer ETJ, Bleijlevens B, de Kreuk BJ, Beurskens FJ, Trouw LA.
    Clin Exp Immunol; 2020 Apr 01; 200(1):1-11. PubMed ID: 31853959
    [Abstract] [Full Text] [Related]

  • 12. The distortive mechanism for the activation of complement component C1 supported by studies with a monoclonal antibody against the "arms" of C1q.
    Hoekzema R, Martens M, Brouwer MC, Hack CE.
    Mol Immunol; 1988 May 01; 25(5):485-94. PubMed ID: 3261834
    [Abstract] [Full Text] [Related]

  • 13. [A stable conformer of IgG, prepared by an acidic influence: study by calorimetry, binding of the C1q complement component, and monospecific anti-IgG].
    Kravchuk ZI, Vlasov AP, Liakhnovich GV, Martsev SP.
    Biokhimiia; 1994 Oct 01; 59(10):1458-77. PubMed ID: 7819387
    [Abstract] [Full Text] [Related]

  • 14. CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering.
    Oostindie SC, van der Horst HJ, Lindorfer MA, Cook EM, Tupitza JC, Zent CS, Burack R, VanDerMeid KR, Strumane K, Chamuleau MED, Mutis T, de Jong RN, Schuurman J, Breij ECW, Beurskens FJ, Parren PWHI, Taylor RP.
    Haematologica; 2019 Sep 01; 104(9):1841-1852. PubMed ID: 30792198
    [Abstract] [Full Text] [Related]

  • 15. Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
    Burvenich IJG, Farrugia W, Liu Z, Makris D, King D, Gloria B, Perani A, Allan LC, Scott AM, Ramsland PA.
    Biochem J; 2018 Jul 05; 475(13):2179-2190. PubMed ID: 29794155
    [Abstract] [Full Text] [Related]

  • 16. Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity.
    Quast I, Keller CW, Maurer MA, Giddens JP, Tackenberg B, Wang LX, Münz C, Nimmerjahn F, Dalakas MC, Lünemann JD.
    J Clin Invest; 2015 Nov 02; 125(11):4160-70. PubMed ID: 26436649
    [Abstract] [Full Text] [Related]

  • 17. IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions.
    Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G.
    Nat Immunol; 2017 Aug 02; 18(8):889-898. PubMed ID: 28604720
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