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Journal Abstract Search

371 related items for PubMed ID: 27320965

  • 1. Fragment Discovery for the Design of Nitrogen Heterocycles as Mycobacterium tuberculosis Dihydrofolate Reductase Inhibitors.
    Shelke RU, Degani MS, Raju A, Ray MK, Rajan MG.
    Arch Pharm (Weinheim); 2016 Aug; 349(8):602-13. PubMed ID: 27320965
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  • 2. Identification of novel selective Mtb-DHFR inhibitors as antitubercular agents through structure-based computational techniques.
    Sharma K, Neshat N, Sharma S, Giri N, Srivastava A, Almalki F, Saifullah K, Alam MM, Shaquiquzzaman M, Akhter M.
    Arch Pharm (Weinheim); 2020 Feb; 353(2):e1900287. PubMed ID: 31867798
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  • 7. In silico structure-based design of a novel class of potent and selective small peptide inhibitor of Mycobacterium tuberculosis Dihydrofolate reductase, a potential target for anti-TB drug discovery.
    Kumar M, Vijayakrishnan R, Subba Rao G.
    Mol Divers; 2010 Aug; 14(3):595-604. PubMed ID: 19697148
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  • 9. Identification of novel DHFR inhibitors for treatment of tuberculosis by combining virtual screening with in vitro activity assay.
    Wang N, Ren JX, Xie Y.
    J Biomol Struct Dyn; 2019 Mar; 37(4):1054-1061. PubMed ID: 29504455
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  • 10. Interactions of 5-deazapteridine derivatives with Mycobacterium tuberculosis and with human dihydrofolate reductases.
    da Cunha EF, de Castro Ramalho T, Bicca de Alencastro R, Maia ER.
    J Biomol Struct Dyn; 2004 Oct; 22(2):119-30. PubMed ID: 15317473
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  • 11. Structural comparison of Mtb-DHFR and h-DHFR for design, synthesis and evaluation of selective non-pteridine analogues as antitubercular agents.
    Sharma K, Tanwar O, Sharma S, Ali S, Alam MM, Zaman MS, Akhter M.
    Bioorg Chem; 2018 Oct; 80():319-333. PubMed ID: 29986181
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  • 13. Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F420H2-dependent reduction.
    Aragaw WW, Lee BM, Yang X, Zimmerman MD, Gengenbacher M, Dartois V, Chui WK, Jackson CJ, Dick T.
    Proc Natl Acad Sci U S A; 2021 Jun 22; 118(25):. PubMed ID: 34161270
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  • 14. Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase.
    Santa Maria JP, Park Y, Yang L, Murgolo N, Altman MD, Zuck P, Adam G, Chamberlin C, Saradjian P, Dandliker P, Boshoff HIM, Barry CE, Garlisi C, Olsen DB, Young K, Glick M, Nickbarg E, Kutchukian PS.
    ACS Chem Biol; 2017 Sep 15; 12(9):2448-2456. PubMed ID: 28806050
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  • 15. Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity.
    Ng HL, Chen S, Chew EH, Chui WK.
    Eur J Med Chem; 2016 Jun 10; 115():63-74. PubMed ID: 26994844
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  • 19. Novel Saccharomyces cerevisiae screen identifies WR99210 analogues that inhibit Mycobacterium tuberculosis dihydrofolate reductase.
    Gerum AB, Ulmer JE, Jacobus DP, Jensen NP, Sherman DR, Sibley CH.
    Antimicrob Agents Chemother; 2002 Nov 10; 46(11):3362-9. PubMed ID: 12384337
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  • 20. Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors.
    Kronenberger T, Ferreira GM, de Souza ADF, da Silva Santos S, Poso A, Ribeiro JA, Tavares MT, Pavan FR, Trossini GHG, Dias MVB, Parise-Filho R.
    Bioorg Med Chem; 2020 Aug 01; 28(15):115600. PubMed ID: 32631571
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