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Journal Abstract Search

198 related items for PubMed ID: 27333281

  • 1. ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain.
    Kühn FJ, Kühn C, Winking M, Hoffmann DC, Lückhoff A.
    PLoS One; 2016; 11(6):e0158060. PubMed ID: 27333281
    [Abstract] [Full Text] [Related]

  • 2. Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR.
    Kühn FJP, Watt JM, Potter BVL, Lückhoff A.
    Sci Rep; 2019 Mar 21; 9(1):4985. PubMed ID: 30899048
    [Abstract] [Full Text] [Related]

  • 3. Different Principles of ADP-Ribose-Mediated Activation and Opposite Roles of the NUDT9 Homology Domain in the TRPM2 Orthologs of Man and Sea Anemone.
    Kühn F, Kühn C, Lückhoff A.
    Front Physiol; 2017 Mar 21; 8():879. PubMed ID: 29163217
    [Abstract] [Full Text] [Related]

  • 4. Functional characterisation of a TRPM2 orthologue from the sea anemone Nematostella vectensis in human cells.
    Kühn FJ, Kühn C, Lückhoff A.
    Sci Rep; 2015 Jan 26; 5():8032. PubMed ID: 25620041
    [Abstract] [Full Text] [Related]

  • 5. Functional importance of NUDT9H domain and N-terminal ADPR-binding pocket in two species variants of vertebrate TRPM2 channels.
    Kühn FJP, Ehrlich W, Barth D, Kühn C, Lückhoff A.
    Sci Rep; 2019 Dec 16; 9(1):19224. PubMed ID: 31844070
    [Abstract] [Full Text] [Related]

  • 6. The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity.
    Iordanov I, Mihályi C, Tóth B, Csanády L.
    Elife; 2016 Jul 06; 5():. PubMed ID: 27383051
    [Abstract] [Full Text] [Related]

  • 7. Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
    Fliegert R, Watt JM, Schöbel A, Rozewitz MD, Moreau C, Kirchberger T, Thomas MP, Sick W, Araujo AC, Harneit A, Potter BVL, Guse AH.
    Biochem J; 2017 Jun 16; 474(13):2159-2175. PubMed ID: 28515263
    [Abstract] [Full Text] [Related]

  • 8. Effects of calcium-binding sites in the S2-S3 loop on human and Nematostella vectensis TRPM2 channel gating processes.
    Luo YH, Yu XF, Ma C, Yang F, Yang W.
    J Zhejiang Univ Sci B; 2017 Jun 16; 20(12):972-982. PubMed ID: 31749344
    [Abstract] [Full Text] [Related]

  • 9. Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates.
    Iordanov I, Tóth B, Szollosi A, Csanády L.
    Elife; 2019 Apr 02; 8():. PubMed ID: 30938679
    [Abstract] [Full Text] [Related]

  • 10. Modulation of activation and inactivation by Ca2+ and 2-APB in the pore of an archetypal TRPM channel from Nematostella vectensis.
    Kühn FJP, Mathis W, Cornelia K, Hoffmann DC, Lückhoff A.
    Sci Rep; 2017 Aug 03; 7(1):7245. PubMed ID: 28775320
    [Abstract] [Full Text] [Related]

  • 11. Selective profiling of N- and C-terminal nucleotide-binding sites in a TRPM2 channel.
    Tóth B, Iordanov I, Csanády L.
    J Gen Physiol; 2020 May 04; 152(5):. PubMed ID: 32211872
    [Abstract] [Full Text] [Related]

  • 12. TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase.
    Fonfria E, Marshall IC, Benham CD, Boyfield I, Brown JD, Hill K, Hughes JP, Skaper SD, McNulty S.
    Br J Pharmacol; 2004 Sep 04; 143(1):186-92. PubMed ID: 15302683
    [Abstract] [Full Text] [Related]

  • 13. Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer.
    Szollosi A, Almássy J.
    Sci Rep; 2023 Jul 15; 13(1):11471. PubMed ID: 37454209
    [Abstract] [Full Text] [Related]

  • 14. Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels.
    Perraud AL, Takanishi CL, Shen B, Kang S, Smith MK, Schmitz C, Knowles HM, Ferraris D, Li W, Zhang J, Stoddard BL, Scharenberg AM.
    J Biol Chem; 2005 Feb 18; 280(7):6138-48. PubMed ID: 15561722
    [Abstract] [Full Text] [Related]

  • 15. TRPM2 causes sensitization to oxidative stress but attenuates high-temperature injury in the sea anemone Nematostella vectensis.
    Ehrlich W, Gahan JM, Rentzsch F, Kühn FJP.
    J Exp Biol; 2022 Mar 15; 225(6):. PubMed ID: 35202476
    [Abstract] [Full Text] [Related]

  • 16. Response to ADP-ribose by activation of TRPM2 in the CRI-G1 insulinoma cell line.
    Inamura K, Sano Y, Mochizuki S, Yokoi H, Miyake A, Nozawa K, Kitada C, Matsushime H, Furuichi K.
    J Membr Biol; 2003 Feb 01; 191(3):201-7. PubMed ID: 12571754
    [Abstract] [Full Text] [Related]

  • 17. Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones.
    Hill K, Tigue NJ, Kelsell RE, Benham CD, McNulty S, Schaefer M, Randall AD.
    Neuropharmacology; 2006 Jan 01; 50(1):89-97. PubMed ID: 16260005
    [Abstract] [Full Text] [Related]

  • 18. Structures and gating mechanism of human TRPM2.
    Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H.
    Science; 2018 Dec 21; 362(6421):. PubMed ID: 30467180
    [Abstract] [Full Text] [Related]

  • 19. Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels.
    Kolisek M, Beck A, Fleig A, Penner R.
    Mol Cell; 2005 Apr 01; 18(1):61-9. PubMed ID: 15808509
    [Abstract] [Full Text] [Related]

  • 20. Role of an N-terminal splice segment in the activation of the cation channel TRPM2 by ADP-ribose and hydrogen peroxide.
    Kühn FJ, Kühn C, Naziroglu M, Lückhoff A.
    Neurochem Res; 2009 Feb 01; 34(2):227-33. PubMed ID: 18521748
    [Abstract] [Full Text] [Related]

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