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Journal Abstract Search

124 related items for PubMed ID: 27337169

  • 1. Effect of Okinawa Propolis on PAK1 Activity, Caenorhabditis elegans Longevity, Melanogenesis, and Growth of Cancer Cells.
    Taira N, Nguyen BC, Be Tu PT, Tawata S.
    J Agric Food Chem; 2016 Jul 13; 64(27):5484-9. PubMed ID: 27337169
    [Abstract] [Full Text] [Related]

  • 2. Artepillin C and Other Herbal PAK1-blockers: Effects on Hair Cell Proliferation and Related PAK1-dependent Biological Function in Cell Culture.
    Nguyen BC, Taira N, Maruta H, Tawata S.
    Phytother Res; 2016 Jan 13; 30(1):120-7. PubMed ID: 26537230
    [Abstract] [Full Text] [Related]

  • 3. From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic PAK1-blockers/longevity-promoters for cancer therapy.
    Maruta H, Ahn MR.
    Eur J Med Chem; 2017 Dec 15; 142():229-243. PubMed ID: 28814374
    [Abstract] [Full Text] [Related]

  • 4. Combination of immunoprecipitation (IP)-ATP_Glo kinase assay and melanogenesis for the assessment of potent and safe PAK1-blockers in cell culture.
    Nguyen BC, Be Tu PT, Tawata S, Maruta H.
    Drug Discov Ther; 2015 Aug 15; 9(4):289-95. PubMed ID: 26370527
    [Abstract] [Full Text] [Related]

  • 5. PAK1-deficiency/down-regulation reduces brood size, activates HSP16.2 gene and extends lifespan in Caenorhabditis elegans.
    Yanase S, Luo Y, Maruta H.
    Drug Discov Ther; 2013 Feb 15; 7(1):29-35. PubMed ID: 23524941
    [Abstract] [Full Text] [Related]

  • 6. Frondoside A from sea cucumber and nymphaeols from Okinawa propolis: Natural anti-cancer agents that selectively inhibit PAK1 in vitro.
    Nguyen BCQ, Yoshimura K, Kumazawa S, Tawata S, Maruta H.
    Drug Discov Ther; 2017 May 30; 11(2):110-114. PubMed ID: 28442678
    [Abstract] [Full Text] [Related]

  • 7. 1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating PAK1 at nM levels.
    Nguyen BC, Kim SA, Won SM, Park SK, Uto Y, Maruta H.
    Drug Discov Ther; 2018 May 30; 12(2):92-96. PubMed ID: 29760342
    [Abstract] [Full Text] [Related]

  • 8. Probiotic microbes: Are their anti-melanogenicity and longevity promoting activities closely linked through the major "pathogenic" kinase PAK1?
    Maruta H, Ahn MR.
    Drug Discov Ther; 2022 May 30; 16(1):43-46. PubMed ID: 35264474
    [Abstract] [Full Text] [Related]

  • 9. Herbal therapeutics that block the oncogenic kinase PAK1: a practical approach towards PAK1-dependent diseases and longevity.
    Maruta H.
    Phytother Res; 2014 May 30; 28(5):656-72. PubMed ID: 23943274
    [Abstract] [Full Text] [Related]

  • 10. 1,2,3-Triazolyl esterization of PAK1-blocking propolis ingredients, artepillin C (ARC) and caffeic acid (CA), for boosting their anti-cancer/anti-PAK1 activities along with cell-permeability.
    Takahashi H, Nguyen BCQ, Uto Y, Shahinozzaman M, Tawata S, Maruta H.
    Drug Discov Ther; 2017 May 30; 11(2):104-109. PubMed ID: 28442677
    [Abstract] [Full Text] [Related]

  • 11. Anti-Inflammatory, Anti-Diabetic, and Anti-Alzheimer's Effects of Prenylated Flavonoids from Okinawa Propolis: An Investigation by Experimental and Computational Studies.
    Shahinozzaman M, Taira N, Ishii T, Halim MA, Hossain MA, Tawata S.
    Molecules; 2018 Sep 27; 23(10):. PubMed ID: 30262742
    [Abstract] [Full Text] [Related]

  • 12. p21-Activated kinase 1 (PAK1) in aging and longevity: An overview.
    Amirthalingam M, Palanisamy S, Tawata S.
    Ageing Res Rev; 2021 Nov 27; 71():101443. PubMed ID: 34390849
    [Abstract] [Full Text] [Related]

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  • 14. Hispidin and related herbal compounds from Alpinia zerumbet inhibit both PAK1-dependent melanogenesis in melanocytes and reactive oxygen species (ROS) production in adipocytes.
    Be Tu PT, Chompoo J, Tawata S.
    Drug Discov Ther; 2015 Jun 27; 9(3):197-204. PubMed ID: 26193942
    [Abstract] [Full Text] [Related]

  • 15. Several herbal compounds in Okinawa plants directly inhibit the oncogenic/aging kinase PAK1.
    Nguyen BC, Taira N, Tawata S.
    Drug Discov Ther; 2014 Dec 27; 8(6):238-44. PubMed ID: 25639302
    [Abstract] [Full Text] [Related]

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  • 17. The serum/PDGF-dependent "melanogenic" role of the minute level of the oncogenic kinase PAK1 in melanoma cells proven by the highly sensitive kinase assay.
    Be Tu PT, Nguyen BC, Tawata S, Yun CY, Kim EG, Maruta H.
    Drug Discov Ther; 2017 Jan 15; 10(6):314-322. PubMed ID: 27746419
    [Abstract] [Full Text] [Related]

  • 18. Rapamycin vs TORin-1 or Gleevec vs Nilotinib: Simple chemical evolution that converts PAK1-blockers to TOR-blockers or vice versa?
    Maruta H, He H.
    Drug Discov Ther; 2024 Jun 06; 18(2):134-139. PubMed ID: 38569833
    [Abstract] [Full Text] [Related]

  • 19. 1,2,3-Triazolyl ester of Ketorolac: A "Click Chemistry"-based highly potent PAK1-blocking cancer-killer.
    Nguyen BCQ, Takahashi H, Uto Y, Shahinozzaman MD, Tawata S, Maruta H.
    Eur J Med Chem; 2017 Jan 27; 126():270-276. PubMed ID: 27889630
    [Abstract] [Full Text] [Related]

  • 20. Hair Growth Promoting and Anticancer Effects of p21-activated kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia zerumbet.
    Taira N, Nguyen BC, Tawata S.
    Molecules; 2017 Jan 14; 22(1):. PubMed ID: 28098826
    [Abstract] [Full Text] [Related]

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