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464 related items for PubMed ID: 27350175

  • 1. Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury.
    Subramanian B, Sun H, Yan P, Charoonratana VT, Higgs HN, Wang F, Lai KV, Valenzuela DM, Brown EJ, Schlöndorff JS, Pollak MR.
    Kidney Int; 2016 Aug; 90(2):363-372. PubMed ID: 27350175
    [Abstract] [Full Text] [Related]

  • 2. Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling.
    Sun H, Schlondorff J, Higgs HN, Pollak MR.
    J Am Soc Nephrol; 2013 May; 24(6):917-29. PubMed ID: 23620398
    [Abstract] [Full Text] [Related]

  • 3. Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2).
    Sun H, Schlondorff JS, Brown EJ, Higgs HN, Pollak MR.
    Proc Natl Acad Sci U S A; 2011 Feb 15; 108(7):2933-8. PubMed ID: 21278336
    [Abstract] [Full Text] [Related]

  • 4. Dysregulated Dynein-Mediated Trafficking of Nephrin Causes INF2-related Podocytopathy.
    Sun H, Perez-Gill C, Schlöndorff JS, Subramanian B, Pollak MR.
    J Am Soc Nephrol; 2021 Feb 15; 32(2):307-322. PubMed ID: 33443052
    [Abstract] [Full Text] [Related]

  • 5. Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus.
    Sun H, Al-Romaih KI, MacRae CA, Pollak MR.
    EBioMedicine; 2014 Dec 15; 1(2-3):107-15. PubMed ID: 26086034
    [Abstract] [Full Text] [Related]

  • 6. Novel mutations in the inverted formin 2 gene of Chinese families contribute to focal segmental glomerulosclerosis.
    Xie J, Hao X, Azeloglu EU, Ren H, Wang Z, Ma J, Liu J, Ma X, Wang W, Pan X, Zhang W, Zhong F, Li Y, Meng G, Kiryluk K, He JC, Gharavi AG, Chen N.
    Kidney Int; 2015 Sep 15; 88(3):593-604. PubMed ID: 26039629
    [Abstract] [Full Text] [Related]

  • 7. FSGS-Causing INF2 Mutation Impairs Cleaved INF2 N-Fragment Functions in Podocytes.
    Subramanian B, Chun J, Perez-Gill C, Yan P, Stillman IE, Higgs HN, Alper SL, Schlöndorff JS, Pollak MR.
    J Am Soc Nephrol; 2020 Feb 15; 31(2):374-391. PubMed ID: 31924668
    [Abstract] [Full Text] [Related]

  • 8. INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy.
    Boyer O, Nevo F, Plaisier E, Funalot B, Gribouval O, Benoit G, Huynh Cong E, Arrondel C, Tête MJ, Montjean R, Richard L, Karras A, Pouteil-Noble C, Balafrej L, Bonnardeaux A, Canaud G, Charasse C, Dantal J, Deschenes G, Deteix P, Dubourg O, Petiot P, Pouthier D, Leguern E, Guiochon-Mantel A, Broutin I, Gubler MC, Saunier S, Ronco P, Vallat JM, Alonso MA, Antignac C, Mollet G.
    N Engl J Med; 2011 Dec 22; 365(25):2377-88. PubMed ID: 22187985
    [Abstract] [Full Text] [Related]

  • 9. The Hippo pathway regulator KIBRA promotes podocyte injury by inhibiting YAP signaling and disrupting actin cytoskeletal dynamics.
    Meliambro K, Wong JS, Ray J, Calizo RC, Towne S, Cole B, El Salem F, Gordon RE, Kaufman L, He JC, Azeloglu EU, Campbell KN.
    J Biol Chem; 2017 Dec 22; 292(51):21137-21148. PubMed ID: 28982981
    [Abstract] [Full Text] [Related]

  • 10. Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ α-1) and profilin 2.
    Rollason R, Wherlock M, Heath JA, Heesom KJ, Saleem MA, Welsh GI.
    Biosci Rep; 2016 Jan 13; 36(1):e00302. PubMed ID: 26764407
    [Abstract] [Full Text] [Related]

  • 11. Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury.
    Blattner SM, Hodgin JB, Nishio M, Wylie SA, Saha J, Soofi AA, Vining C, Randolph A, Herbach N, Wanke R, Atkins KB, Gyung Kang H, Henger A, Brakebusch C, Holzman LB, Kretzler M.
    Kidney Int; 2013 Nov 13; 84(5):920-30. PubMed ID: 23677246
    [Abstract] [Full Text] [Related]

  • 12. Missense Mutant Gain-of-Function Causes Inverted Formin 2 (INF2)-Related Focal Segmental Glomerulosclerosis (FSGS).
    Subramanian B, Williams S, Karp S, Hennino MF, Jacas S, Lee M, Riella CV, Alper SL, Higgs HN, Pollak MR.
    bioRxiv; 2024 Jun 10. PubMed ID: 38915495
    [Abstract] [Full Text] [Related]

  • 13. Mutational screening of inverted formin 2 in adult-onset focal segmental glomerulosclerosis or minimal change patients from the Czech Republic.
    Safarikova M, Stekrova J, Honsova E, Horinova V, Tesar V, Reiterova J.
    BMC Med Genet; 2018 Aug 20; 19(1):147. PubMed ID: 30126379
    [Abstract] [Full Text] [Related]

  • 14. Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis.
    Brown EJ, Schlöndorff JS, Becker DJ, Tsukaguchi H, Tonna SJ, Uscinski AL, Higgs HN, Henderson JM, Pollak MR.
    Nat Genet; 2010 Jan 20; 42(1):72-6. PubMed ID: 20023659
    [Abstract] [Full Text] [Related]

  • 15. Variable renal phenotype in a family with an INF2 mutation.
    Lee HK, Han KH, Jung YH, Kang HG, Moon KC, Ha IS, Choi Y, Cheong HI.
    Pediatr Nephrol; 2011 Jan 20; 26(1):73-6. PubMed ID: 20803156
    [Abstract] [Full Text] [Related]

  • 16. Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes.
    Babayeva S, Zilber Y, Torban E.
    Am J Physiol Renal Physiol; 2011 Feb 20; 300(2):F549-60. PubMed ID: 20534871
    [Abstract] [Full Text] [Related]

  • 17. Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture.
    New LA, Martin CE, Scott RP, Platt MJ, Keyvani Chahi A, Stringer CD, Lu P, Samborska B, Eremina V, Takano T, Simpson JA, Quaggin SE, Jones N.
    J Am Soc Nephrol; 2016 Aug 20; 27(8):2422-35. PubMed ID: 26802179
    [Abstract] [Full Text] [Related]

  • 18. Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes.
    Yanagida-Asanuma E, Asanuma K, Kim K, Donnelly M, Young Choi H, Hyung Chang J, Suetsugu S, Tomino Y, Takenawa T, Faul C, Mundel P.
    Am J Pathol; 2007 Aug 20; 171(2):415-27. PubMed ID: 17569780
    [Abstract] [Full Text] [Related]

  • 19. SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.
    Rogg M, Maier JI, Dotzauer R, Artelt N, Kretz O, Helmstädter M, Abed A, Sammarco A, Sigle A, Sellung D, Dinse P, Reiche K, Yasuda-Yamahara M, Biniossek ML, Walz G, Werner M, Endlich N, Schilling O, Huber TB, Schell C.
    J Am Soc Nephrol; 2021 Mar 20; 32(3):563-579. PubMed ID: 33514561
    [Abstract] [Full Text] [Related]

  • 20. Role of formin INF2 in human diseases.
    Zhao Y, Zhang H, Wang H, Ye M, Jin X.
    Mol Biol Rep; 2022 Jan 20; 49(1):735-746. PubMed ID: 34698992
    [Abstract] [Full Text] [Related]

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