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441 related items for PubMed ID: 27376928
1. Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity. Guzmán EA, Xu Q, Pitts TP, Mitsuhashi KO, Baker C, Linley PA, Oestreicher J, Tendyke K, Winder PL, Suh EM, Wright AE. Int J Cancer; 2016 Nov 01; 139(9):2116-26. PubMed ID: 27376928 [Abstract] [Full Text] [Related]
2. A novel colchicine-based microtubule inhibitor exhibits potent antitumor activity by inducing mitochondrial mediated apoptosis in MIA PaCa-2 pancreatic cancer cells. Kumar A, Singh B, Mahajan G, Sharma PR, Bharate SB, Mintoo MJ, Mondhe DM. Tumour Biol; 2016 Oct 01; 37(10):13121-13136. PubMed ID: 27449046 [Abstract] [Full Text] [Related]
3. PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors. Martínez-Díez M, Guillén-Navarro MJ, Pera B, Bouchet BP, Martínez-Leal JF, Barasoain I, Cuevas C, Andreu JM, García-Fernández LF, Díaz JF, Avilés P, Galmarini CM. Biochem Pharmacol; 2014 Apr 01; 88(3):291-302. PubMed ID: 24486569 [Abstract] [Full Text] [Related]
4. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo. Cai D, Qiu Z, Yao W, Liu Y, Huang H, Liao S, Luo Q, Xie L, Lin Z. Cancer Chemother Pharmacol; 2016 Jun 01; 77(6):1217-29. PubMed ID: 27107592 [Abstract] [Full Text] [Related]
5. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site. Boichuk S, Galembikova A, Syuzov K, Dunaev P, Bikinieva F, Aukhadieva A, Zykova S, Igidov N, Gankova K, Novikova M, Kopnin P. Molecules; 2021 Sep 24; 26(19):. PubMed ID: 34641324 [Abstract] [Full Text] [Related]
6. The marine natural product Scalarin inhibits the receptor for advanced glycation end products (RAGE) and autophagy in the PANC-1 and MIA PaCa-2 pancreatic cancer cell lines. Guzmán EA, Pitts TP, Diaz MC, Wright AE. Invest New Drugs; 2019 Apr 24; 37(2):262-270. PubMed ID: 29998364 [Abstract] [Full Text] [Related]
7. Estradiol dimer inhibits tubulin polymerization and microtubule dynamics. Jurášek M, Černohorská M, Řehulka J, Spiwok V, Sulimenko T, Dráberová E, Darmostuk M, Gurská S, Frydrych I, Buriánová R, Ruml T, Hajdúch M, Bartůněk P, Dráber P, Džubák P, Drašar PB, Sedlák D. J Steroid Biochem Mol Biol; 2018 Oct 24; 183():68-79. PubMed ID: 29803726 [Abstract] [Full Text] [Related]
8. Analogues of the Potent Antitumor Compound Leiodermatolide from a Deep-Water Sponge of the Genus Leiodermatium. Wright AE, Roberts JC, Guzmán EA, Pitts TP, Pomponi SA, Reed JK. J Nat Prod; 2017 Mar 24; 80(3):735-739. PubMed ID: 28135095 [Abstract] [Full Text] [Related]
9. LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity. Qin M, Peng S, Liu N, Hu M, He Y, Li G, Chen H, He Y, Chen A, Wang X, Liu M, Chen Y, Yi Z. J Pharmacol Exp Ther; 2015 Dec 24; 355(3):473-83. PubMed ID: 26377911 [Abstract] [Full Text] [Related]
10. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell. Hasanpourghadi M, Karthikeyan C, Pandurangan AK, Looi CY, Trivedi P, Kobayashi K, Tanaka K, Wong WF, Mustafa MR. J Exp Clin Cancer Res; 2016 Mar 31; 35():58. PubMed ID: 27030360 [Abstract] [Full Text] [Related]
11. Antitumor Activity of Asperphenin A, a Lipopeptidyl Benzophenone from Marine-Derived Aspergillus sp. Fungus, by Inhibiting Tubulin Polymerization in Colon Cancer Cells. Bae SY, Liao L, Park SH, Kim WK, Shin J, Lee SK. Mar Drugs; 2020 Feb 13; 18(2):. PubMed ID: 32069904 [Abstract] [Full Text] [Related]
12. A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer. Ahn S, Hwang DJ, Barrett CM, Yang J, Duke CB, Miller DD, Dalton JT. Cancer Chemother Pharmacol; 2011 Feb 13; 67(2):293-304. PubMed ID: 20383708 [Abstract] [Full Text] [Related]
13. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells. Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X. Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540 [Abstract] [Full Text] [Related]
14. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities. Liu Z, Zhou Z, Tian W, Fan X, Xue D, Yu L, Yu Q, Long YQ. ChemMedChem; 2012 Apr 01; 7(4):680-93. PubMed ID: 22311585 [Abstract] [Full Text] [Related]
15. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules. Kamath K, Okouneva T, Larson G, Panda D, Wilson L, Jordan MA. Mol Cancer Ther; 2006 Sep 01; 5(9):2225-33. PubMed ID: 16985056 [Abstract] [Full Text] [Related]
16. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition. Viola G, Cecconet L, Leszl A, Basso G, Brun P, Salvador A, Dall'Acqua F, Diana P, Barraja P, Cirrincione G. Cancer Chemother Pharmacol; 2009 Nov 01; 64(6):1235-51. PubMed ID: 19363609 [Abstract] [Full Text] [Related]
17. 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells. Levrier C, Sadowski MC, Rockstroh A, Gabrielli B, Kavallaris M, Lehman M, Davis RA, Nelson CC. Mol Cancer Ther; 2017 Jan 01; 16(1):3-15. PubMed ID: 27760837 [Abstract] [Full Text] [Related]
18. A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity. Du T, Lin S, Ji M, Xue N, Liu Y, Zhang Z, Zhang K, Zhang J, Zhang Y, Wang Q, Sheng L, Li Y, Lu D, Chen X, Xu H. Cancer Lett; 2020 Dec 28; 495():22-32. PubMed ID: 32931884 [Abstract] [Full Text] [Related]
19. Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity. Arora S, Wang XI, Keenan SM, Andaya C, Zhang Q, Peng Y, Welsh WJ. Cancer Res; 2009 Mar 01; 69(5):1910-5. PubMed ID: 19223556 [Abstract] [Full Text] [Related]
20. NMK-TD-100, a novel microtubule modulating agent, blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Bhattacharya S, Kumar NM, Ganguli A, Tantak MP, Kumar D, Chakrabarti G. PLoS One; 2013 Mar 01; 8(10):e76286. PubMed ID: 24116100 [Abstract] [Full Text] [Related] Page: [Next] [New Search]